Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models VF Lazarev, DV Sverchinsky, ER Mikhaylova, PI Semenyuk, ... Cell death & disease 9 (2), 41, 2018 | 47 | 2018 |
Hsp70 chaperone rescues C6 rat glioblastoma cells from oxidative stress by sequestration of aggregating GAPDH VF Lazarev, AD Nikotina, ER Mikhaylova, E Nudler, SG Polonik, ... Biochemical and biophysical research communications 470 (3), 766-771, 2016 | 41 | 2016 |
Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma EY Komarova, RV Suezov, AD Nikotina, ND Aksenov, LA Garaeva, ... Scientific reports 11 (1), 21314, 2021 | 40 | 2021 |
Etoposide-induced apoptosis in cancer cells can be reinforced by an uncoupled link between Hsp70 and caspase-3 DV Sverchinsky, AD Nikotina, EY Komarova, ER Mikhaylova, ND Aksenov, ... International journal of molecular sciences 19 (9), 2519, 2018 | 34 | 2018 |
Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress VF Lazarev, AD Nikotina, PI Semenyuk, DB Evstafyeva, ER Mikhaylova, ... Free Radical Biology and Medicine 92, 29-38, 2016 | 31 | 2016 |
Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells AD Nikotina, L Koludarova, EY Komarova, ER Mikhaylova, ND Aksenov, ... Oncotarget 9 (43), 27268, 2018 | 29 | 2018 |
Extracellular GAPDH promotes alzheimer disease progression by enhancing amyloid-β aggregation and cytotoxicity VF Lazarev, M Tsolaki, ER Mikhaylova, KA Benken, MA Shevtsov, ... Aging and disease 12 (5), 1223, 2021 | 23 | 2021 |
Extracellular Hsp70 reduces the pro-tumor capacity of monocytes/macrophages co-cultivated with cancer cells EY Komarova, LV Marchenko, AV Zhakhov, AD Nikotina, ND Aksenov, ... International Journal of Molecular Sciences 21 (1), 59, 2019 | 22 | 2019 |
Co-expression of RelA/p65 and ACTN4 induces apoptosis in non-small lung carcinoma cells E Lomert, L Turoverova, D Kriger, ND Aksenov, AD Nikotina, A Petukhov, ... Cell Cycle 17 (5), 616-626, 2018 | 22 | 2018 |
Glyceraldehyde 3‐phosphate dehydrogenase augments the intercellular transmission and toxicity of polyglutamine aggregates in a cell model of Huntington disease ER Mikhaylova, VF Lazarev, AD Nikotina, BA Margulis, IV Guzhova Journal of neurochemistry 136 (5), 1052-1063, 2016 | 20 | 2016 |
Prevention of High Glucose-Mediated EMT by inhibition of Hsp70 chaperone AD Nikotina, SA Vladimirova, EY Komarova, D Alexeev, S Efremov, ... International Journal of Molecular Sciences 22 (13), 6902, 2021 | 9 | 2021 |
Phenotypic characteristics of macrophages and tumor cells in coculture LV Marchenko, AD Nikotina, ND Aksenov, LV Smagina, BA Margulis, ... Cell and Tissue Biology 12, 351-358, 2018 | 6 | 2018 |
Properties of substances inhibiting aggregation of oxidized GAPDH: Data on the interaction with the enzyme and the impact on its intracellular content VF Lazarev, AD Nikotina, PI Semenyuk, DB Evstafyeva, ER Mikhaylova, ... Data in brief 7, 524-528, 2016 | 5 | 2016 |
Novel mechanism of drug resistance triggered by tumor-associated macrophages through Heat Shock Factor-1 activation AD Nikotina, SA Vladimirova, NE Kokoreva, VA Nevdakha, VF Lazarev, ... Cancer Immunology, Immunotherapy 73 (2), 25, 2024 | 3 | 2024 |
Combined cytotoxic effect of inhibitors of proteostasis on human colon cancer cells AD Nikotina, SA Vladimirova, NE Kokoreva, EY Komarova, ND Aksenov, ... Pharmaceuticals 15 (8), 923, 2022 | 3 | 2022 |
Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex DV Sverchinsky, BA Alhasan, MA Mikeladze, VF Lazarev, LS Kuznetcova, ... Journal of Experimental & Clinical Cancer Research 42 (1), 279, 2023 | 2 | 2023 |
Guzhova IV. Hsp70-containing extracellular vesicles are capable of activating of adaptive immunity in models of mouse melanoma and colon carcinoma. Sci Rep. 2021; 11 EY Komarova, RV Suezov, AD Nikotina, ND Aksenov, LA Garaeva, ... | 2 | |
Effect of the HSF1 inhibitor Cl-43 on tumors and non-transformed cells SA Vladimirova, BA Margulis, IV Guzhova, AD Nikotina Citologiâ 66 (2), 143-149, 2024 | | 2024 |
CARDENOLIDE CL-43 PROMOTES PROTEASOMAL DEGRADATION OF HSFI IN COLORECTAL CANCER CELLS AV Erofeeva, AD Nikotina, BA Margulis, IV Guzhova Genes & Cells 15 (3S), 88-89, 2020 | | 2020 |
HSP70 PROMOTES THE EPITHELIAL-MESENCHYMAL TRANSITION IN DLD1 HUMAN COLON CANCER CELLS SA Vladimirova, AD Nikotina, DA Alexeev, BA Margulis, IV Guzhova Genes & Cells 15 (S3), 82-82, 2020 | | 2020 |