Chemically induced degradation of the oncogenic transcription factor BCL6 N Kerres, S Steurer, S Schlager, G Bader, H Berger, M Caligiuri, C Dank, ... Cell reports 20 (12), 2860-2875, 2017 | 160 | 2017 |
Pharmacologic inhibition of STAT5 in acute myeloid leukemia B Wingelhofer, B Maurer, EC Heyes, AA Cumaraswamy, A Berger-Becvar, ... Leukemia 32 (5), 1135-1146, 2018 | 141 | 2018 |
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression S Terlecki-Zaniewicz, T Humer, T Eder, J Schmoellerl, E Heyes, ... Nature structural & molecular biology 28 (2), 190-201, 2021 | 65 | 2021 |
Gain‐of‐Function Effects of N‐Terminal CEBPA Mutations in Acute Myeloid Leukemia L Schmidt, E Heyes, F Grebien BioEssays 42 (2), 1900178, 2020 | 24 | 2020 |
CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex L Schmidt, E Heyes, L Scheiblecker, T Eder, G Volpe, J Frampton, ... Leukemia 33 (7), 1608-1619, 2019 | 24 | 2019 |
Core-binding factor leukemia hijacks the T-cell–prone PU. 1 antisense promoter E van der Kouwe, G Heller, A Czibere, JA Pulikkan, C Agreiter, ... Blood, The Journal of the American Society of Hematology 138 (15), 1345-1358, 2021 | 15 | 2021 |
Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML E Heyes, L Schmidt, G Manhart, T Eder, L Proietti, F Grebien Leukemia 35 (9), 2526-2538, 2021 | 15 | 2021 |
Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness AM Grandits, CH Nguyen, A Schlerka, H Hackl, H Sill, J Etzler, E Heyes, ... Leukemia 35 (10), 2827-2839, 2021 | 10 | 2021 |
Abstract LB-108: A potent and selective small molecule degrader of STAT5 for the treatment of hematological malignancies JS Park, G Tin, ED de Araujo, A Orlova, H Sorger, F Grebien, E Heyes, ... Cancer Research 80 (16_Supplement), LB-108-LB-108, 2020 | 6 | 2020 |
Arrayed CRISPR/Cas9 Screening for the Functional Validation of Cancer Genetic Dependencies L Proietti, G Manhart, E Heyes, S Troester, F Grebien Bio-protocol 12 (24), e4577-e4577, 2022 | 2 | 2022 |
TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression E Heyes, AS Wilhelmson, A Wenzel, G Manhart, T Eder, MB Schuster, ... Nature Communications 14 (1), 6185, 2023 | 1 | 2023 |
Regimen-dependent synergism and antagonism of treprostinil and vildagliptin in hematopoietic cell transplantation E Zebedin-Brandl, M Themanns, Z Kazemi, S Nasrollahi-Shirazi, ... Journal of Molecular Medicine 98, 233-243, 2020 | 1 | 2020 |
TET2 lesions enhance the aggressiveness of CEBPA-mutant AML by rebalancing GATA2 expression E Heyes, AS Wilhelmson, A Wenzel, G Manhart, T Eder, MB Schuster, ... bioRxiv, 2023.03. 28.534511, 2023 | | 2023 |
P467: FUNCTIONAL CHARACTERIZATION OF ABERRANT GATA1 PROTEIN COMPLEXES IN NORMAL AND MALIGNANT HUMAN ERYTHROBLASTS S Tauchmann, FO Bagger, T Bock, R Sivalingam, T Eder, E Heyes, ... HemaSphere 6, 366-367, 2022 | | 2022 |
P444: IDENTIFICATION OF FUNCTIONAL GENETIC DEPENDENCIES IN CEBPA-MUTATED ACUTE MYELOID LEUKEMIA L Proietti, E Heyes, T Eder, T Brandstoetter, G Manhart, V Sexl, F Grebien HemaSphere 6, 344-345, 2022 | | 2022 |
S119: CEBPA AND TET2 MUTATIONS COOPERATE TO INDUCE AGGRESSIVE AML VIA GATA-2 DOWNREGULATION E Heyes, AS Wilhelmson, A Wenzel, MB Schuster, M Ali, T D’Altri, T Eder, ... HemaSphere 6, 20-21, 2022 | | 2022 |
Biomolecular Condensation Drives Leukemia Caused by NUP98-Fusion Proteins S Terlecki-Zaniewicz, T Eder, J Schmöllerl, T Humer, N Kuchynka, ... bioRxiv, 2020.11. 16.384271, 2020 | | 2020 |
PS966 FUNCTIONAL COOPERATION OF CEBPA AND TET2 MUTATIONS IN ACUTE MYELOID LEUKEMIA E Heyes, L Schmidt, T Eder, G Manhart, G Volpe, C Nerlov, J Frampton, ... HemaSphere 3 (S1), 435, 2019 | | 2019 |
CEBPA-Mutant Acute Myeloid Leukemia is Sensitive to Small-Molecule-Mediated Inhibition of the Menin-MLL Interaction L Schmidt, E Heyes, L Scheiblecker, T Eder, G Volpe, J Frampton, ... Experimental Hematology 64, S101, 2018 | | 2018 |
Functional cooperation of CEBPA and TET2 mutations in Acute Myeloid Leukemia E Heyes, L Schmidt, T Eder, G Volpe, K Chatziathanasiou, C Schmidt, ... ONCOLOGY RESEARCH AND TREATMENT 41, 40-40, 2018 | | 2018 |