Encapsulation of temozolomide in a calixarene nanocapsule improves its stability and enhances its therapeutic efficacy against glioblastoma A Renziehausen, AD Tsiailanis, R Perryman, EK Stylos, C Chatzigiannis, ... Molecular cancer therapeutics 18 (9), 1497-1505, 2019 | 33 | 2019 |
Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL TF Kellici, MV Chatziathanasiadou, MS Lee, N Sayyad, EG Geromichalou, ... Organic & biomolecular chemistry 15 (37), 7956-7976, 2017 | 28 | 2017 |
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid AD Tsiailanis, A Renziehausen, S Kiriakidi, EI Vrettos, GS Markopoulos, ... Free Radical Biology and Medicine 160, 391-402, 2020 | 19 | 2020 |
Tailoring naringenin conjugates with amplified and triple antiplatelet activity profile: Rational design, synthesis, human plasma stability and in vitro evaluation E Stylos, MV Chatziathanasiadou, A Tsiailanis, TF Kellici, M Tsoumani, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (11), 2609-2618, 2017 | 17 | 2017 |
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma R Perryman, A Renziehausen, H Shaye, AD Kostagianni, AD Tsiailanis, ... Proceedings of the National Academy of Sciences 119 (32), e2116289119, 2022 | 11 | 2022 |
Chemical Profiling, Bioactivity Evaluation and the Discovery of a Novel Biopigment Produced by Penicillium purpurogenum CBS 113139 AD Tsiailanis, C Pateraki, M Kyriazou, CM Chatzigiannis, ... Molecules 27 (1), 69, 2021 | 5 | 2021 |
Advancing the therapeutic efficacy of bioactive molecules by delivery vehicle platforms AD Tsiailanis, AG Tzakos, T Mavromoustakos Current Medicinal Chemistry 28 (14), 2697-2706, 2021 | 5 | 2021 |
Designing natural product hybrids bearing triple antiplatelet profile and evaluating their human plasma stability A Tsiailanis, M Tsoumani, EK Stylos, MV Chatziathanasiadou, TF Kellici, ... Rational Drug Design: Methods and Protocols, 371-385, 2018 | 5 | 2018 |
The NMR tube bioreactor AV Chatzikonstantinou, AD Tsiailanis, IP Gerothanassis, H Stamatis, ... Methods in Enzymology 633, 71-101, 2020 | 4 | 2020 |
Using conformational constraints at position 6 of Angiotensin II to generate compounds with enhanced AT2R selectivity and proteolytic stability D Tourwé, AD Tsiailanis, N Parisis, B Hirmiz, M Del Borgo, MI Aguilar, ... Bioorganic & Medicinal Chemistry Letters 43, 128086, 2021 | 2 | 2021 |
Exploiting the beneficial effects of Salvia officinalis L. extracts in human health and assessing their activity as potent functional regulators of food microbiota V Kompoura, I Karapantzou, G Mitropoulou, NA Parisis, VK Gkalpinos, ... Food Chemistry 441, 138175, 2024 | 1 | 2024 |
Encapsulation of Small Drugs in a Supramolecule Enhances Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme AD Tsiailanis, A Renziehausen, S Karakurt, T Crook, N Syed, AG Tzakos Supramolecules in Drug Discovery and Drug Delivery: Methods and Protocols …, 2021 | 1 | 2021 |
Nrf2 down-regulation mediates pro-inflammatory effects of novel synthetic AhR ligands I Koprivica, N Jonić, C Chatzigiannis, A Tsiailanis, AG Tzakos, ... 5th Scientific Meeting of the COST Action CA20121: Bench to Bedside …, 2023 | | 2023 |
Development of a DHA-Losartan hybrid as a potent inhibitor of multiple pathway-induced platelet aggregation AD Tsiailanis, EI Vrettos, M Choleva, S Kiriakidi, AM Ganai, TK Patha, ... Journal of Biomolecular Structure and Dynamics 40 (24), 13889-13900, 2022 | | 2022 |
EXTH-14. INHIBITION OF THE ANGIOTENSIN II TYPE 2 RECEPTOR AT2R IS A NOVEL THERAPEUTIC STRATEGY FOR GLIOBLASTOMA IOMASA POTENT Neuro-oncology, 2022 | | 2022 |
Biophysical Evaluation and In Vitro Controlled Release of Two Isomeric Adamantane Phenylalkylamines with Antiproliferative/Anticancer and Analgesic Activity M Vlachou, AS Foscolos, A Siamidi, A Syriopoulou, N Georgiou, ... Molecules 27 (1), 7, 2021 | | 2021 |