| Preparative scale expression of membrane proteins in Escherichia coli-based continuous exchange cell-free systems D Schwarz, F Junge, F Durst, N Frölich, B Schneider, S Reckel, ... Nature protocols 2 (11), 2945-2957, 2007 | 310 | 2007 |
| Evaluation of detergents for the soluble expression of α‐helical and β‐barrel‐type integral membrane proteins by a preparative scale individual cell‐free expression system C Klammt, D Schwarz, K Fendler, W Haase, V Dötsch, F Bernhard The FEBS journal 272 (23), 6024-6038, 2005 | 279 | 2005 |
| Large-scale production of functional membrane proteins F Junge, B Schneider, S Reckel, D Schwarz, V Dötsch, F Bernhard Cellular and Molecular Life Sciences 65, 1729-1755, 2008 | 214 | 2008 |
| Cell‐free expression as an emerging technique for the large scale production of integral membrane protein C Klammt, D Schwarz, F Löhr, B Schneider, V Dötsch, F Bernhard The FEBS journal 273 (18), 4141-4153, 2006 | 210 | 2006 |
| Cell-free production of G protein-coupled receptors for functional and structural studies C Klammt, D Schwarz, N Eifler, A Engel, J Piehler, W Haase, S Hahn, ... Journal of structural biology 158 (3), 482-493, 2007 | 163 | 2007 |
| Production of membrane proteins using cell‐free expression systems D Schwarz, V Dötsch, F Bernhard Proteomics 8 (19), 3933-3946, 2008 | 150 | 2008 |
| A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease T Dale, PA Clarke, C Esdar, D Waalboer, O Adeniji-Popoola, ... Nature chemical biology 11 (12), 973, 2015 | 132 | 2015 |
| Structural basis for tail-anchored membrane protein biogenesis by the Get3-receptor complex S Stefer, S Reitz, F Wang, K Wild, YY Pang, D Schwarz, J Bomke, C Hein, ... Science 333 (6043), 758-762, 2011 | 128 | 2011 |
| Discovery of potent, selective, and orally bioavailable small-molecule modulators of the mediator complex-associated kinases CDK8 and CDK19 A Mallinger, K Schiemann, C Rink, F Stieber, M Calderini, S Crumpler, ... Journal of medicinal chemistry 59 (3), 1078-1101, 2016 | 115 | 2016 |
| Membrane protein expression in cell-free systems B Schneider, F Junge, VA Shirokov, F Durst, D Schwarz, V Dötsch, ... Heterologous Expression of Membrane Proteins: Methods and Protocols, 165-186, 2010 | 115 | 2010 |
| Cell-free expression and stable isotope labelling strategies for membrane proteins S Sobhanifar, S Reckel, F Junge, D Schwarz, L Kai, M Karbyshev, F Löhr, ... Journal of biomolecular NMR 46, 33-43, 2010 | 115 | 2010 |
| Structure-based optimization of potent, selective, and orally bioavailable CDK8 inhibitors discovered by high-throughput screening P Czodrowski, A Mallinger, D Wienke, C Esdar, O Pöschke, M Busch, ... Journal of medicinal chemistry 59 (20), 9337-9349, 2016 | 106 | 2016 |
| Preparative scale cell-free expression systems: new tools for the large scale preparation of integral membrane proteins for functional and structural studies D Schwarz, C Klammt, A Koglin, F Löhr, B Schneider, V Dötsch, ... Methods 41 (4), 355-369, 2007 | 105 | 2007 |
| Structural and biophysical characterization of the Syk activation switch U Grädler, D Schwarz, V Dresing, D Musil, J Bomke, M Frech, H Greiner, ... Journal of molecular biology 425 (2), 309-333, 2013 | 98 | 2013 |
| Cell free expression and functional reconstitution of eukaryotic drug transporters T Keller, D Schwarz, F Bernhard, V Dötsch, C Hunte, V Gorboulev, ... Biochemistry 47 (15), 4552-4564, 2008 | 81 | 2008 |
| Kinetic and structural insights into the mechanism of binding of sulfonamides to human carbonic anhydrase by computational and experimental studies R Gaspari, C Rechlin, A Heine, G Bottegoni, W Rocchia, D Schwarz, ... Journal of Medicinal Chemistry 59 (9), 4245-4256, 2016 | 67 | 2016 |
| Combination of cell‐free expression and NMR spectroscopy as a new approach for structural investigation of membrane proteins A Koglin, C Klammt, N Trbovic, D Schwarz, B Schneider, B Schäfer, ... Magnetic Resonance in Chemistry 44 (S1), S17-S23, 2006 | 56 | 2006 |
| Functional analysis of cell‐free‐produced human endothelin B receptor reveals transmembrane segment 1 as an essential area for ET‐1 binding and homodimer formation C Klammt, A Srivastava, N Eifler, F Junge, M Beyermann, D Schwarz, ... The FEBS Journal 274 (13), 3257-3269, 2007 | 52 | 2007 |
| 2, 8-Disubstituted-1, 6-naphthyridines and 4, 6-disubstituted-isoquinolines with potent, selective affinity for CDK8/19 A Mallinger, K Schiemann, C Rink, J Sejberg, MA Honey, P Czodrowski, ... ACS medicinal chemistry letters 7 (6), 573-578, 2016 | 50 | 2016 |
| Cell-free production of integral membrane proteins on a preparative scale C Klammt, D Schwarz, V Dötsch, F Bernhard In Vitro Transcription and Translation Protocols, 57-78, 2007 | 47 | 2007 |
DötschVerified email at em.uni-frankfurt.de
