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Kenneth Goossens
Kenneth Goossens
Galapagos
Verified email at glpg.com
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Year
ClpP protease, a promising antimicrobial target
C Moreno-Cinos, K Goossens, IG Salado, P Van Der Veken, H De Winter, ...
International journal of molecular sciences 20 (9), 2232, 2019
982019
Discovery of novel, drug-like ferroptosis inhibitors with in vivo efficacy
L Devisscher, S Van Coillie, S Hofmans, D Van Rompaey, K Goossens, ...
Journal of medicinal chemistry 61 (22), 10126-10140, 2018
962018
Molecular dynamics simulations of membrane proteins: An overview
K Goossens, H De Winter
Journal of chemical information and modeling 58 (11), 2193-2202, 2018
682018
Tozasertib analogues as inhibitors of necroptotic cell death
S Hofmans, L Devisscher, S Martens, D Van Rompaey, K Goossens, ...
Journal of Medicinal Chemistry 61 (5), 1895-1920, 2018
372018
Assessment of the fragment docking program SEED
K Goossens, B Wroblowski, C Langini, H van Vlijmen, A Caflisch, ...
Journal of chemical information and modeling 60 (10), 4881-4893, 2020
122020
A Computational and Modeling Study of the Reaction Mechanism of Staphylococcus aureus Monoglycosyltransferase Reveals New Insights on the GT51 Family of …
K Goossens, RPP Neves, PA Fernandes, H De Winter
Journal of Chemical Information and Modeling 60 (11), 5513-5528, 2020
42020
From PERK to RIPK1: Design, synthesis and evaluation of novel potent and selective necroptosis inhibitors
C Scarpellini, S Valembois, K Goossens, M Vadi, C Lanthier, ...
Frontiers in Chemistry 11, 1160164, 2023
22023
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′ N modification provides for improved microtubule binding, persistent cytotoxicity …
Y Ma, F Josa-Prado, JN Essif, S Liu, S Li, D Lucena-Agell, PYW Chan, ...
European Journal of Medicinal Chemistry 259, 115668, 2023
2023
Computational investigation of the catalytic mechanism and dynamics of Staphylococcus aureus glycosyltransferase towards development of novel antibiotics
K Goossens
University of Antwerp, 2021
2021
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Articles 1–9