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Won Kyun Koh
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Divergent effects of Dnmt3a and Tet2 mutations on hematopoietic progenitor cell fitness
EL Ostrander, AC Kramer, C Mallaney, H Celik, WK Koh, J Fairchild, ...
Stem cell reports 14 (4), 551-560, 2020
702020
Kdm6b regulates context-dependent hematopoietic stem cell self-renewal and leukemogenesis
C Mallaney, EL Ostrander, H Celik, AC Kramer, A Martens, A Kothari, ...
Leukemia 33 (10), 2506-2521, 2019
582019
JARID2 functions as a tumor suppressor in myeloid neoplasms by repressing self-renewal in hematopoietic progenitor cells
H Celik, WK Koh, AC Kramer, EL Ostrander, C Mallaney, DAC Fisher, ...
Cancer cell 34 (5), 741-756. e8, 2018
512018
Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis
PY Lin, SM Simon, WK Koh, O Folorunso, CS Umbaugh, A Pierce
Molecular neurodegeneration 8, 1-17, 2013
502013
14-3-3 proteins restrain the Exo1 nuclease to prevent overresection
X Chen, IK Kim, Y Honaker, SC Paudyal, WK Koh, M Sparks, S Li, ...
Journal of Biological Chemistry 290 (19), 12300-12312, 2015
272015
A humanized animal model predicts clonal evolution and therapeutic vulnerabilities in myeloproliferative neoplasms
H Celik, E Krug, CR Zhang, W Han, N Issa, WK Koh, H Bjeije, O Kukhar, ...
Cancer discovery 11 (12), 3126-3141, 2021
242021
Txnip Enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells via p21
CR Zhang, EL Ostrander, O Kukhar, C Mallaney, J Sun, E Haussler, ...
Blood cancer discovery 3 (3), 220-239, 2022
112022
The GNASR201C mutation associated with clonal hematopoiesis supports transplantable hematopoietic stem cell activity
EL Ostrander, WK Koh, C Mallaney, AC Kramer, WC Wilson, B Zhang, ...
Experimental hematology 57, 14-20, 2018
62018
DNMT3A Regulates Hematopoietic Stem Cell Function Via DNA Methylation-Independent Functions
WK Koh, H Celik, J Tao, J Fairchild, O Kukhar, CR Zhang, P Gontarz, ...
Blood 138, 24, 2021
32021
The Histone Demethylase KDM6B Is a genetic dependency of NOTCH1-driven T-ALL
N Issa, H Celik, H Bjeije, WMB Dunuwille, WK Koh, T Parsons, CR Zhang, ...
Blood 138, 782, 2021
12021
3225–DNA METHYLATION-INDEPENDENT FUNCTIONS OF DNMT3A REGULATE HEMATOPOIETIC STEM CELL FUNCTION
IX Raj, WK Koh, J Harrison, C Zhang, J Arand, H Bjeije, W Han, A Young, ...
Experimental Hematology 124, S162, 2023
2023
DNMT3A Mutations Enhance T-ALL Survival, Which Is Reversed By JAK/STAT Inhibition
W Dunuwille, WC Wilson, N Issa, WK Koh, W Han, GA Challen
Blood 140 (Supplement 1), 8756-8757, 2022
2022
Abstract LB555: Augmented Txnip-p53-p21 axis preserves Dnmt3a mutant hematopoietic stem cells during inflammatory stress
CR Zhang, E Ostrander, WK Koh, O Kukhar, H Celik, J Magee, G Challen
Cancer Research 82 (12_Supplement), LB555-LB555, 2022
2022
DNMT3A Regulates Hematopoietic Stem Cells via DNA Methylation-Independent Functions
WK Koh
Washington University in St. Louis, 2022
2022
Txnip enhances Fitness of Dnmt3a-Mutant Hematopoietic Stem Cells Via p21
CR Zhang, EL Ostrander, J Sun, C Mallaney, H Celik, WK Koh, KY King, ...
Blood 138, 600, 2021
2021
A Novel Humanized Animal Model Reveals Clonal Architecture and Therapeutic Vulnerabilities in Myelofibrosis
H Celik, E Krug, H Bjeije, N Issa, W Han, WK Koh, RCZ Zhang, MJ Allen, ...
Blood 136, 17-18, 2020
2020
Jarid2 Restricts Long-Term Repopulating Stem Cell Capacity in Multipotent Progenitors and Acts As Tumor Suppressor in Chronic Myeloid Neoplasms
H Celik, WK Koh, EL Ostrander, AC Kramer, WC Wilson, G Fishberger, ...
Blood 130, 488, 2017
2017
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Articles 1–17