| Structure of the trypanosome cyanide-insensitive alternative oxidase T Shiba, Y Kido, K Sakamoto, DK Inaoka, C Tsuge, R Tatsumi, ... Proceedings of the National Academy of Sciences 110 (12), 4580-4585, 2013 | 212 | 2013 |
| Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL G Karpel-Massler, CT Ishida, E Bianchetti, Y Zhang, C Shu, T Tsujiuchi, ... Nature communications 8, 1067, 2017 | 114 | 2017 |
| Metabolic Reprogramming by Dual AKT/ERK Inhibition through Imipridones Elicits Unique Vulnerabilities in Glioblastomac-myc Levels Predict Therapeutic Responses to Imipridones CT Ishida, Y Zhang, E Bianchetti, C Shu, TTT Nguyen, G Kleiner, ... Clinical Cancer Research 24 (21), 5392-5406, 2018 | 74 | 2018 |
| Inhibition of mitochondrial matrix chaperones and anti-apoptotic Bcl-2 family proteins empower antitumor therapeutic responses G Karpel-Massler, CT Ishida, E Bianchetti, C Shu, R Perez-Lorenzo, ... Cancer Research, canres. 3424.2016, 2017 | 64 | 2017 |
| Targeting intrinsic apoptosis and other forms of cell death by BH3-mimetics in glioblastoma G Karpel-Massler, CT Ishida, Y Zhang, ME Halatsch, MA Westhoff, ... Expert opinion on drug discovery 12 (10), 1031-1040, 2017 | 45 | 2017 |
| Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in GlioblastomaTargeting the Epigenome Reprograms Glioblastoma … Y Zhang, CT Ishida, W Ishida, SFL Lo, J Zhao, C Shu, E Bianchetti, ... Clinical Cancer Research 24 (16), 3941-3954, 2018 | 42 | 2018 |
| Activation of LXR β inhibits tumor respiration and is synthetically lethal with Bcl‐xL inhibition TTT Nguyen, CT Ishida, E Shang, C Shu, C Torrini, Y Zhang, E Bianchetti, ... EMBO Molecular Medicine 11 (10), e10769, 2019 | 39 | 2019 |
| BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma CT Ishida, E Bianchetti, C Shu, ME Halatsch, MA Westhoff, ... Oncotarget 8 (18), 29558, 2017 | 39 | 2017 |
| Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei EO Balogun, DK Inaoka, T Shiba, C Tsuge, B May, T Sato, Y Kido, T Nara, ... The FASEB Journal 33 (11), 13002-13013, 2019 | 25 | 2019 |
| Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase T Shiba, DK Inaoka, G Takahashi, C Tsuge, Y Kido, L Young, S Ueda, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1860 (5), 375-382, 2019 | 24 | 2019 |
| Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma CT Ishida, C Shu, ME Halatsch, MA Westhoff, DC Altieri, G Karpel-Massler, ... Oncotarget 8 (23), 2017 | 23 | 2017 |
| Activation of LXR receptors and inhibition of TRAP1 causes synthetic lethality in solid tumors TTT Nguyen, CT Ishida, E Shang, C Shu, E Bianchetti, G Karpel-Massler, ... Cancers 11 (6), 788, 2019 | 22 | 2019 |
| Dual Inhibition of Bcl-2/Bcl-xL and XPO1 is synthetically lethal in glioblastoma model systems E Shang, Y Zhang, C Shu, CT Ishida, E Bianchetti, MA Westhoff, ... Scientific Reports 8 (1), 1-11, 2018 | 20 | 2018 |
| Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase EO Balogun, DK Inaoka, T Shiba, Y Kido, C Tsuge, T Nara, T Aoki, ... Molecular microbiology 94 (6), 1315-1329, 2014 | 16 | 2014 |
| Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma Y Zhang, CT Ishida, C Shu, G Kleiner, MJ Sanchez-Quintero, E Bianchetti, ... Scientific Reports 8 (1), 1-12, 2018 | 12 | 2018 |
| BH3-mimetics and BET-inhibitors elicit enhanced lethality in malignant glioma. Oncotarget 8, 29558–29573 CT Ishida, E Bianchetti, C Shu, ME Halatsch, MA Westhoff, ... | 7 | 2017 |
| Siccanin is a novel selective inhibitor of trypanosomatid complex II (succinate-ubiquinone reductase) and a potent broad-spectrum anti-trypanosomatid drug candidate N Nihashi, DK Inaoka, C Tsuge, EO Balogun, Y Osada, Y Goto, ... Kala Azar in South Asia: Current Status and Sustainable Challenges, 101-122, 2016 | 6 | 2016 |
| IDH1 R132H predicts sensitivity to Bcl-xL inhibition-mediated programmed cell death G Karpel-Massler, CT Ishida, MD Siegelin Oncotarget 9 (1), 1, 2018 | 1 | 2018 |
| Nucleotidases Exhibit Enzymatic Activities Toward the Pharmacologically Active Metabolites of Gemcitabine and Emtricitabine H Seneviratne, NR Phulara, C Ishida, P Espenshade Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
| Assaying Sterol-Regulated ER-to-Golgi Transport of SREBP Cleavage-Activating Protein Using Immunofluorescence Microscopy PJE Chiaki T Ishida, Wei Shao Golgi 2557, 755-764, 2022 | | 2022 |
