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Zhenze Jiang
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Skin commensal Malassezia globosa secreted protease attenuates Staphylococcus aureus biofilm formation
H Li, BN Goh, WK Teh, Z Jiang, JPZ Goh, A Goh, G Wu, SS Hoon, ...
Journal of Investigative Dermatology 138 (5), 1137-1145, 2018
1192018
Targeting proteasomes in infectious organisms to combat disease
B Bibo‐Verdugo, Z Jiang, CR Caffrey, AJ O'Donoghue
The FEBS journal 284 (10), 1503-1517, 2017
622017
Dysregulation of exosome cargo by mutant tau expressed in human-induced pluripotent stem cell (iPSC) neurons revealed by proteomics analyses
S Podvin, A Jones, Q Liu, B Aulston, L Ransom, J Ames, G Shen, CB Lietz, ...
Molecular & Cellular Proteomics 19 (6), 1017-1034, 2020
382020
The Pseudomonas aeruginosa protease LasB directly activates IL-1β
J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, ...
EBioMedicine 60, 2020
372020
Selective neutral pH inhibitor of cathepsin B designed based on cleavage preferences at cytosolic and lysosomal pH conditions
MC Yoon, A Solania, Z Jiang, MP Christy, S Podvin, C Mosier, CB Lietz, ...
ACS chemical biology 16 (9), 1628-1643, 2021
322021
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry
JD Lapek*, Z Jiang*, JM Wozniak, E Arutyunova, SC Wang, MJ Lemieux, ...
Molecular & Cellular Proteomics, mcp. TIR118. 001099, 2019
312019
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties
A Leontovyč, L Ulrychová, AJ O’Donoghue, J Vondrášek, L Marešová, ...
PLoS neglected tropical diseases 12 (4), e0006446, 2018
292018
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni
B Bibo-Verdugo, SC Wang, J Almaliti, AP Ta, Z Jiang, DA Wong, CB Lietz, ...
ACS infectious diseases 5 (10), 1802-1812, 2019
262019
An enzyme-free signal amplification strategy for sensitive detection of microRNA via catalyzed hairpin assembly
Z Jiang*, H Wang*, X Zhang, C Liu, Z Li
Analytical Methods 6 (23), 9477-9482, 2014
262014
Insights into the catalytic properties of the mitochondrial rhomboid protease PARL
L Lysyk, R Brassard, E Arutyunova, V Siebert, Z Jiang, E Takyi, ...
Journal of Biological Chemistry 296, 2021
232021
20S proteasome as a drug target in Trichomonas vaginalis
AJ O’Donoghue, B Bibo-Verdugo, Y Miyamoto, SC Wang, JZ Yang, ...
Antimicrobial agents and chemotherapy 63 (11), 10.1128/aac. 00448-19, 2019
232019
Differential neuropeptidomes of dense core secretory vesicles (DCSV) produced at intravesicular and extracellular pH conditions by proteolytic processing
Z Jiang, CB Lietz, S Podvin, MC Yoon, T Toneff, V Hook, AJ O’Donoghue
ACS chemical neuroscience 12 (13), 2385-2398, 2021
162021
An internally quenched peptide as a new model substrate for rhomboid intramembrane proteases
E Arutyunova*, Z Jiang*, J Yang, AN Kulepa, HS Young, S Verhelst, ...
Biological chemistry 399 (12), 1389-1397, 2018
152018
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro
JH Xu*, Z Jiang*, A Solania, S Chatterjee, B Suzuki, CB Lietz, VYH Hook, ...
ACS chemical biology 13 (9), 2513-2521, 2018
152018
Dysregulation of neuropeptide and tau peptide signatures in human Alzheimer’s disease brain
S Podvin, Z Jiang, B Boyarko, LA Rossitto, A O’Donoghue, RA Rissman, ...
ACS Chemical Neuroscience 13 (13), 1992-2005, 2022
132022
Engineering of multiple trypsin/chymotrypsin sites in Cry3A to enhance its activity against Monochamus alternatus Hope larvae
Y Guo, Y Wang, AJ O'Donoghue, Z Jiang, R Carballar‐Lejarazú, G Liang, ...
Pest Management Science 76 (9), 3117-3126, 2020
132020
High-resolution mass spectrometry-based approaches for the detection and quantification of peptidase activity in plasma
E Maffioli, Z Jiang, S Nonnis, A Negri, V Romeo, CB Lietz, V Hook, ...
Molecules 25 (18), 4071, 2020
122020
Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome
C Beekman, Z Jiang, BM Suzuki, JM Palmer, DL Lindner, AJ O’Donoghue, ...
Biological Chemistry 399 (12), 1375-1388, 2018
112018
Mutant presenilin 1 dysregulates exosomal proteome cargo produced by human-induced pluripotent stem cell neurons
S Podvin, A Jones, Q Liu, B Aulston, C Mosier, J Ames, C Winston, ...
ACS omega 6 (20), 13033-13056, 2021
92021
Distinct dibasic cleavage specificities of neuropeptide-producing cathepsin L and cathepsin V cysteine proteases compared to PC1/3 and PC2 serine proteases
MC Yoon, J Ames, C Mosier, Z Jiang, S Podvin, AJ O’Donoghue, V Hook
ACS chemical neuroscience 13 (2), 245-256, 2022
82022
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