Skin commensal Malassezia globosa secreted protease attenuates Staphylococcus aureus biofilm formation H Li, BN Goh, WK Teh, Z Jiang, JPZ Goh, A Goh, G Wu, SS Hoon, ... Journal of Investigative Dermatology 138 (5), 1137-1145, 2018 | 119 | 2018 |
Targeting proteasomes in infectious organisms to combat disease B Bibo‐Verdugo, Z Jiang, CR Caffrey, AJ O'Donoghue The FEBS journal 284 (10), 1503-1517, 2017 | 62 | 2017 |
Dysregulation of exosome cargo by mutant tau expressed in human-induced pluripotent stem cell (iPSC) neurons revealed by proteomics analyses S Podvin, A Jones, Q Liu, B Aulston, L Ransom, J Ames, G Shen, CB Lietz, ... Molecular & Cellular Proteomics 19 (6), 1017-1034, 2020 | 38 | 2020 |
The Pseudomonas aeruginosa protease LasB directly activates IL-1β J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, ... EBioMedicine 60, 2020 | 37 | 2020 |
Selective neutral pH inhibitor of cathepsin B designed based on cleavage preferences at cytosolic and lysosomal pH conditions MC Yoon, A Solania, Z Jiang, MP Christy, S Podvin, C Mosier, CB Lietz, ... ACS chemical biology 16 (9), 1628-1643, 2021 | 32 | 2021 |
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry JD Lapek*, Z Jiang*, JM Wozniak, E Arutyunova, SC Wang, MJ Lemieux, ... Molecular & Cellular Proteomics, mcp. TIR118. 001099, 2019 | 31 | 2019 |
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties A Leontovyč, L Ulrychová, AJ O’Donoghue, J Vondrášek, L Marešová, ... PLoS neglected tropical diseases 12 (4), e0006446, 2018 | 29 | 2018 |
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni B Bibo-Verdugo, SC Wang, J Almaliti, AP Ta, Z Jiang, DA Wong, CB Lietz, ... ACS infectious diseases 5 (10), 1802-1812, 2019 | 26 | 2019 |
An enzyme-free signal amplification strategy for sensitive detection of microRNA via catalyzed hairpin assembly Z Jiang*, H Wang*, X Zhang, C Liu, Z Li Analytical Methods 6 (23), 9477-9482, 2014 | 26 | 2014 |
Insights into the catalytic properties of the mitochondrial rhomboid protease PARL L Lysyk, R Brassard, E Arutyunova, V Siebert, Z Jiang, E Takyi, ... Journal of Biological Chemistry 296, 2021 | 23 | 2021 |
20S proteasome as a drug target in Trichomonas vaginalis AJ O’Donoghue, B Bibo-Verdugo, Y Miyamoto, SC Wang, JZ Yang, ... Antimicrobial agents and chemotherapy 63 (11), 10.1128/aac. 00448-19, 2019 | 23 | 2019 |
Differential neuropeptidomes of dense core secretory vesicles (DCSV) produced at intravesicular and extracellular pH conditions by proteolytic processing Z Jiang, CB Lietz, S Podvin, MC Yoon, T Toneff, V Hook, AJ O’Donoghue ACS chemical neuroscience 12 (13), 2385-2398, 2021 | 16 | 2021 |
An internally quenched peptide as a new model substrate for rhomboid intramembrane proteases E Arutyunova*, Z Jiang*, J Yang, AN Kulepa, HS Young, S Verhelst, ... Biological chemistry 399 (12), 1389-1397, 2018 | 15 | 2018 |
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro JH Xu*, Z Jiang*, A Solania, S Chatterjee, B Suzuki, CB Lietz, VYH Hook, ... ACS chemical biology 13 (9), 2513-2521, 2018 | 15 | 2018 |
Dysregulation of neuropeptide and tau peptide signatures in human Alzheimer’s disease brain S Podvin, Z Jiang, B Boyarko, LA Rossitto, A O’Donoghue, RA Rissman, ... ACS Chemical Neuroscience 13 (13), 1992-2005, 2022 | 13 | 2022 |
Engineering of multiple trypsin/chymotrypsin sites in Cry3A to enhance its activity against Monochamus alternatus Hope larvae Y Guo, Y Wang, AJ O'Donoghue, Z Jiang, R Carballar‐Lejarazú, G Liang, ... Pest Management Science 76 (9), 3117-3126, 2020 | 13 | 2020 |
High-resolution mass spectrometry-based approaches for the detection and quantification of peptidase activity in plasma E Maffioli, Z Jiang, S Nonnis, A Negri, V Romeo, CB Lietz, V Hook, ... Molecules 25 (18), 4071, 2020 | 12 | 2020 |
Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome C Beekman, Z Jiang, BM Suzuki, JM Palmer, DL Lindner, AJ O’Donoghue, ... Biological Chemistry 399 (12), 1375-1388, 2018 | 11 | 2018 |
Mutant presenilin 1 dysregulates exosomal proteome cargo produced by human-induced pluripotent stem cell neurons S Podvin, A Jones, Q Liu, B Aulston, C Mosier, J Ames, C Winston, ... ACS omega 6 (20), 13033-13056, 2021 | 9 | 2021 |
Distinct dibasic cleavage specificities of neuropeptide-producing cathepsin L and cathepsin V cysteine proteases compared to PC1/3 and PC2 serine proteases MC Yoon, J Ames, C Mosier, Z Jiang, S Podvin, AJ O’Donoghue, V Hook ACS chemical neuroscience 13 (2), 245-256, 2022 | 8 | 2022 |