Modelling of pancreatic cancer biology: Transcriptomic signature for 3D PDX-derived organoids and primary cell line organoid development SR Nelson, C Zhang, S Roche, F O’Neill, N Swan, Y Luo, AM Larkin, ... Scientific Reports 10 (1), 2778, 2020 | 40 | 2020 |
Genetic alterations featuring biological models to tailor clinical management of pancreatic cancer patients SR Nelson, N Walsh Cancers 12 (5), 1233, 2020 | 6 | 2020 |
Genomic Profiling and Functional Analysis of let-7c miRNA-mRNA Interactions Identify SOX13 to Be Involved in Invasion and Progression of Pancreatic Cancer SR Nelson, S Roche, M Cotter, PA Garcia, D Reitmeier, E Zollbrecht, ... Journal of Oncology 2020, 2020 | 5 | 2020 |
Pancreatic cancer 3D cell line organoids (CLOs) Maintain the phenotypic characteristics of organoids and accurately reflect the cellular architecture and heterogeneity in vivo S Noorani, SR Nelson, NT Conlon, J Meiller, E Shcheglova, A Usai, ... Organoids 1 (2), 168-183, 2022 | 2 | 2022 |
Serendipity meets synergism: differential enantiomer activities of a RAD51-BRCA2 disruptor towards a more robust synthetic lethality in pancreatic cancer S Girotto, M Masi, L Poppi, V Previtali, S Nelson, G Varignani, ... | | 2024 |
Novel organoid models for the functional validation of pancreatic cancer genomic variants SR Nelson Dublin City University, 2022 | | 2022 |
Analysis of the role of maturity onset diabetes of the young (MODY) pathway transcription factors in pancreatic cancer SR Nelson, C Andrieu, J Crown, D Harold, N Walsh IRISH JOURNAL OF MEDICAL SCIENCE 190 (SUPPL 2), 68-68, 2021 | | 2021 |
Assessment of pancreatic cancer 3D organotypic cultures as models for functional preclinical analysis SR Nelson, S Roche, F O'Neill, AM Larkin, J Crown, N Walsh Cancer Research 79 (13_Supplement), 44-44, 2019 | | 2019 |
Therapeutic resistance of 3D pancreatic cancer tumorspheres involves differential cancer stem cell response N Walsh, S Nelson, S Roche, F O'neill, J Crown EUROPEAN JOURNAL OF CANCER 103, E113-E114, 2018 | | 2018 |
Optimisation of protocols for the establishment of pancreatic cancer organoids and cell lines from patient derived xenografts (PDX) tumour models S Nelson, S Roche, F O'neill, A Larkin, J Crown, N Walsh EUROPEAN JOURNAL OF CANCER 103, E108-E108, 2018 | | 2018 |