| The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018 | 1301 | 2018 |
| Childhood cancer predisposition syndromes—a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology T Ripperger, SS Bielack, A Borkhardt, IB Brecht, B Burkhardt, ... American journal of medical genetics Part A 173 (4), 1017-1037, 2017 | 299 | 2017 |
| Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 211 | 2020 |
| The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation AM Tremblay, E Missiaglia, GG Galli, S Hettmer, R Urcia, M Carrara, ... Cancer cell 26 (2), 273-287, 2014 | 180 | 2014 |
| Muscling in: Uncovering the origins of rhabdomyosarcoma S Hettmer, AJ Wagers Nature medicine 16 (2), 171-173, 2010 | 162 | 2010 |
| The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets CM Van Tilburg, E Pfaff, KW Pajtler, KPS Langenberg, P Fiesel, BC Jones, ... Cancer discovery 11 (11), 2764-2779, 2021 | 137 | 2021 |
| Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers S Hettmer, NM Archer, GR Somers, A Novokmet, AJ Wagers, L Diller, ... Cancer 120 (7), 1068-1075, 2014 | 120 | 2014 |
| Lineage of origin in rhabdomyosarcoma informs pharmacological response J Abraham, Y Nuñez-Álvarez, S Hettmer, E Carrió, HIH Chen, K Nishijo, ... Genes & development 28 (14), 1578-1591, 2014 | 112 | 2014 |
| Inhibition of melanoma tumor growth by a novel inhibitor of glucosylceramide synthase M Weiss, S Hettmer, P Smith, S Ladisch Cancer research 63 (13), 3654-3658, 2003 | 111 | 2003 |
| Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease CM Hung, CM Calejman, J Sanchez-Gurmaches, H Li, CB Clish, ... Cell reports 8 (1), 256-271, 2014 | 105 | 2014 |
| Rhabdomyosarcoma: current challenges and their implications for developing therapies S Hettmer, Z Li, AN Billin, FG Barr, DDW Cornelison, AR Ehrlich, ... Cold Spring Harbor perspectives in medicine 4 (11), a025650, 2014 | 84 | 2014 |
| Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells S Hettmer, J Liu, CM Miller, MC Lindsay, CA Sparks, DA Guertin, ... Proceedings of the National Academy of Sciences 108 (50), 20002-20007, 2011 | 82 | 2011 |
| Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle A Castiglioni, S Hettmer, MD Lynes, TN Rao, D Tchessalova, I Sinha, ... Stem cell reports 2 (1), 92-106, 2014 | 76 | 2014 |
| Insights into pediatric rhabdomyosarcoma research: Challenges and goals ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ... Pediatric blood & cancer 66 (10), e27869, 2019 | 72 | 2019 |
| Efficient generation of iPS cells from skeletal muscle stem cells KY Tan, S Eminli, S Hettmer, K Hochedlinger, AJ Wagers PloS one 6 (10), e26406, 2011 | 70 | 2011 |
| Feasibility of intraventricular administration of etoposide in patients with metastatic brain tumours G Fleischhack, S Reif, C Hasan, U Jaehde, S Hettmer, U Bode British journal of cancer 84 (11), 1453-1459, 2001 | 66 | 2001 |
| Personalized clinical decision making through implementation of a molecular tumor board: a German single-center experience R Hoefflin, AL Geißler, R Fritsch, R Claus, J Wehrle, P Metzger, M Reiser, ... JCO Precision Oncology 2, 1-16, 2018 | 64 | 2018 |
| Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma S Hettmer, AC Schinzel, D Tchessalova, M Schneider, CL Parker, ... Elife 4, e09436, 2015 | 64 | 2015 |
| A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development X Le, EK Pugach, S Hettmer, NY Storer, J Liu, AA Wills, A DiBiase, ... Development 140 (11), 2354-2364, 2013 | 63 | 2013 |
| Pathology of childhood rhabdomyosarcoma: a consensus opinion document from the children's oncology group, European paediatric soft tissue sarcoma study group, and the … ER Rudzinski, A Kelsey, C Vokuhl, CM Linardic, J Shipley, S Hettmer, ... Pediatric blood & cancer 68 (3), e28798, 2021 | 49 | 2021 |
