John Challiss
John Challiss
Professor of Molecular & Cellular Pharmacology, University of Leicester
Verified email at - Homepage
Cited by
Cited by
Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes
CD Nicholson, RAJ Challiss, M Shahid
Trends in Pharmacological Sciences 12, 19-27, 1991
Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors
E Hermans, RAJ Challiss
Biochemical Journal 359, 465-484, 2001
Neuronal Ca2+ stores: activation and function
PB Simpson, RAJ Challiss, SR Nahorski
Trends in Neurosciences 18 (7), 299-306, 1995
Muscarinic acetylcholine receptor subtypes in smooth muscle
RM Eglen, H Reddy, N Watson, RAJ Challiss
Trends in Pharmacological Sciences 15 (4), 114-119, 1994
Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences
SR Nahorski, CI Ragan, RAJ Challiss
Trends in Pharmacological Sciences 12, 297-303, 1991
Mass measurements of inositol 1,4,5-trisphosphate in rat cerebral cortex slices using a radioreceptor assay: effects of neurotransmitters and depolarization
RAJ Challiss, IH Batty, SR Nahorski
Biochemical and Biophysical Research Communications 157 (2), 684-691, 1988
Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells
GB Willars, SR Nahorski, RAJ Challiss
Journal of Biological Chemistry 273 (9), 5037-5046, 1998
Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse
JR Steinert, C Kopp-Scheinpflug, C Baker, RAJ Challiss, R Mistry, ...
Neuron 60 (4), 642-656, 2008
Heterogeneity of [3H]inositol 1,4,5-trisphosphate binding sites in adrenal-cortical membranes: characterization and validation of a radioreceptor assay
RAJ Challiss, ER Chilvers, AL Willcocks, SR Nahorski
Biochemical Journal 265, 421-427, 1990
Receptor-specific messenger oscillations
MS Nash, KW Young, RA John Challiss, SR Nahorski
Nature 413 (6854), 381-382, 2001
Biochemical adaptation in the skeletal muscle of rats depleted of creatine with the substrate analogue β-guanidinopropionic acid
EA Shoubridge, RAJ Challiss, DJ Hayes, GK Radda
Biochemical Journal 232, 125-131, 1985
Non-visual GRKs: are we seeing the whole picture?
JM Willets, RAJ Challiss, SR Nahorski
Trends in Pharmacological Sciences 24 (12), 626-633, 2003
Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma
A Sutcliffe, F Hollins, E Gomez, R Saunders, C Doe, MD Cooke, ...
American Journal of Respiratory and Critical Care Medicine 185 (3), 267-274, 2012
The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats
GD Dimitriadis, M Parry-Billings, S Bevan, B Leighton, U Krause, T Piva, ...
European Journal of Clinical Investigation 27 (6), 475-483, 1997
Phosphorus-31 NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo
KM Brindle, MJ Blackledge, RAJ Challiss, GK Radda
Biochemistry 28 (11), 4887-4893, 1989
Determinants of metabotropic glutamate receptor-5 (mGlu5)-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency
MS Nash, MJ Schell, PJ Atkinson, NR Johnston, SR Nahorski, ...
Journal of Biological Chemistry 277 (39), 35947-35960, 2002
Group‐I metabotropic glutamate receptors, mGlu1a and mGlu5a, couple to extracellular signal‐regulated kinase (ERK) activation via distinct, but overlapping, signalling pathways
S Thandi, JL Blank, RAJ Challiss
Journal of Neurochemistry 83 (5), 1139-1153, 2002
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor
RA Wilcox, WU Primrose, SR Nahorski, RAJ Challiss
Trends in Pharmacological Sciences 19 (11), 467-475, 1998
Gq/11 and Gi/o activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor‐subtype
EC Akam, RAJ Challiss, SR Nahorski
British Journal of Pharmacology 132 (4), 950-958, 2001
The effect of prostaglandins E1, E2 and F2α and indomethacin on the sensitivity of glycolysis and glycogen synthesis to insulin in stripped soleus muscles of the rat
B Leighton, L Budohoski, FJ Lozeman, RAJ Challiss, EA Newsholme
Biochemical Journal 227 (1), 337, 1985
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