The p53/p21 complex regulates cancer cell invasion and apoptosis by targeting Bcl-2 family proteins EM Kim, CH Jung, J Kim, SG Hwang, JK Park, HD Um Cancer research 77 (11), 3092-3100, 2017 | 201 | 2017 |
Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway CH Jung, EM Kim, JK Park, SG Hwang, SK Moon, WJ Kim, HD Um Oncology reports 29 (6), 2109-2113, 2013 | 108 | 2013 |
Acquired resistance to cetuximab is mediated by increased PTEN instability and leads cross-resistance to gefitinib in HCC827 NSCLC cells SM Kim, JS Kim, JH Kim, CO Yun, EM Kim, HK Kim, F Solca, SY Choi, ... Cancer letters 296 (2), 150-159, 2010 | 79 | 2010 |
Cooperative actions of p21WAF1 and p53 induce Slug protein degradation and suppress cell invasion J Kim, S Bae, S An, JK Park, EM Kim, SG Hwang, WJ Kim, HD Um EMBO reports 15 (10), 1062-1068, 2014 | 74 | 2014 |
Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy JY Choi, WG Hong, JH Cho, EM Kim, J Kim, CH Jung, SG Hwang, HD Um, ... International journal of oncology 47 (4), 1257-1265, 2015 | 71 | 2015 |
Amplification of the γ-irradiation-induced cell death pathway by reactive oxygen species in human U937 cells EM Kim, HS Yang, SW Kang, JN Ho, SB Lee, HD Um Cellular signalling 20 (5), 916-924, 2008 | 61 | 2008 |
Heat shock protein 60 modified with O-linked N-acetylglucosamine is involved in pancreatic β-cell death under hyperglycemic conditions HS Kim, EM Kim, J Lee, WH Yang, TY Park, YM Kim, JW Cho FEBS letters 580 (9), 2311-2316, 2006 | 51 | 2006 |
Nuclear and cytoplasmic p53 suppress cell invasion by inhibiting respiratory complex-I activity via Bcl-2 family proteins EM Kim, JK Park, SG Hwang, WJ Kim, ZG Liu, SW Kang, HD Um Oncotarget 5 (18), 8452, 2014 | 50 | 2014 |
Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax EM Kim, J Kim, JK Park, SG Hwang, WJ Kim, WJ Lee, SW Kang, HD Um Cellular signalling 24 (6), 1163-1172, 2012 | 40 | 2012 |
Mitochondrial superoxide dismutase 2 mediates γ-irradiation-induced cancer cell invasion CH Jung, EM Kim, JY Song, JK Park, HD Um Experimental & Molecular Medicine 51 (2), 1-10, 2019 | 31 | 2019 |
Pro-apoptotic Bax promotes mesenchymal-epithelial transition by binding to respiratory complex-I and antagonizing the malignant actions of pro-survival Bcl-2 proteins EM Kim, CH Jung, JY Song, JK Park, HD Um Cancer letters 424, 127-135, 2018 | 26 | 2018 |
Differential TM4SF5‐mediated SIRT1 modulation and metabolic signaling in nonalcoholic steatohepatitis progression J Ryu, E Kim, MK Kang, DG Song, EA Shin, H Lee, JW Jung, SH Nam, ... The Journal of Pathology 253 (1), 55-67, 2021 | 22 | 2021 |
TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, ... Cell Reports 37 (7), 2021 | 16 | 2021 |
TM4SF5-mediated liver malignancy involves NK cell exhaustion-like phenotypes H Sun, E Kim, J Ryu, H Lee, EA Shin, M Lee, H Lee, JH Lee, JH Yoon, ... Cellular and Molecular Life Sciences, 1-20, 2021 | 15 | 2021 |
Amino acid transporters as tetraspanin TM4SF5 binding partners JW Jung, JE Kim, E Kim, JW Lee Experimental & Molecular Medicine 52 (1), 7-14, 2020 | 15 | 2020 |
Involvement of SULF2 in γ-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression CH Jung, JN Ho, JK Park, EM Kim, SG Hwang, HD Um Oncotarget 7 (13), 16090, 2016 | 15 | 2016 |
p21WAF1/CIP1 promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interaction J Lee, J Kim, EM Kim, U Kim, AR Kang, JK Park, HD Um Biochemical and biophysical research communications 543, 23-28, 2021 | 14 | 2021 |
N-terminus-independent activation of c-Src via binding to a tetraspan (in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application HE Song, Y Lee, E Kim, CY Cho, O Jung, D Lee, EG Lee, SH Nam, ... Theranostics 11 (16), 8092, 2021 | 11 | 2021 |
Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis H Lee, E Kim, EA Shin, JC Shon, H Sun, JE Kim, JW Jung, H Lee, ... Molecular Metabolism 58, 101451, 2022 | 10 | 2022 |
Src and epidermal growth factor receptor mediate the pro-invasive activity of Bcl-w EM Kim, JK Park, SG Hwang, HD Um Tumor Biology 37, 1245-1252, 2016 | 10 | 2016 |