关注
Hengameh Shams
Hengameh Shams
Computational Chemist, Denali Therapeutics Inc.
在 dnli.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mechanotransduction pathways linking the extracellular matrix to the nucleus
Z Jahed, H Shams, M Mehrbod, MRK Mofrad
International review of cell and molecular biology 310, 171-220, 2014
1332014
Actin reorganization through dynamic interactions with single-wall carbon nanotubes
H Shams, BD Holt, SH Mahboobi, Z Jahed, MF Islam, KN Dahl, ...
ACS nano 8 (1), 188-197, 2014
512014
A molecular trajectory of α-actinin activation
H Shams, J Golji, MRK Mofrad
Biophysical journal 103 (10), 2050-2059, 2012
422012
Altered cell mechanics from the inside: dispersed single wall carbon nanotubes integrate with and restructure actin
BD Holt, H Shams, TA Horst, S Basu, AD Rape, YL Wang, GK Rohde, ...
Journal of functional biomaterials 3 (2), 398-417, 2012
422012
A disulfide bond is required for the transmission of forces through SUN-KASH complexes
Z Jahed, H Shams, MRK Mofrad
Biophysical Journal 109 (3), 501-509, 2015
382015
Kindlin assists talin to promote integrin activation
Z Haydari, H Shams, Z Jahed, MRK Mofrad
Biophysical journal 118 (8), 1977-1991, 2020
372020
Dynamic regulation of α-actinin’s calponin homology domains on F-actin
H Shams, J Golji, K Garakani, MRK Mofrad
Biophysical journal 110 (6), 1444-1455, 2016
352016
Mechanisms of integrin and filamin binding and their interplay with talin during early focal adhesion formation
T Truong, H Shams, MRK Mofrad
Integrative biology 7 (10), 1285-1296, 2015
282015
Polygenic risk score association with multiple sclerosis susceptibility and phenotype in Europeans
H Shams, X Shao, A Santaniello, G Kirkish, A Harroud, Q Ma, N Isobe, ...
Brain 146 (2), 645-656, 2023
242023
High-resolution characterization of KIR genes in a large North American Cohort reveals novel details of structural and sequence diversity
LM Amorim, DG Augusto, N Nemat-Gorgani, G Montero-Martin, WM Marin, ...
Frontiers in Immunology 12, 674778, 2021
212021
Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis
A Didonna, E Canto Puig, Q Ma, A Matsunaga, B Ho, SJ Caillier, H Shams, ...
Proceedings of the National Academy of Sciences 117 (38), 23742-23750, 2020
192020
Mechanosensitive conformation of vinculin regulates its binding to MAPK1
K Garakani, H Shams, MRK Mofrad
Biophysical journal 112 (9), 1885-1893, 2017
192017
Looking “under the Hood” of cellular Mechanotransduction with computational tools: a systems biomechanics approach across multiple scales
H Shams, M Soheilypour, M Peyro, R Moussavi-Baygi, MRK Mofrad
ACS biomaterials science & engineering 3 (11), 2712-2726, 2017
182017
Steric regulation of tandem calponin homology domain actin-binding affinity
AR Harris, B Belardi, P Jreij, K Wei, H Shams, A Bausch, DA Fletcher
Molecular biology of the cell 30 (26), 3112-3122, 2019
172019
α-Actinin induces a kink in the transmembrane domain of β3-integrin and impairs activation via talin
H Shams, MRK Mofrad
Biophysical journal 113 (4), 948-956, 2017
172017
Killer cell immunoglobulin-like receptor variants are associated with protection from symptoms associated with more severe course in Parkinson disease
KM Anderson, DG Augusto, R Dandekar, H Shams, C Zhao, T Yusufali, ...
The Journal of Immunology 205 (5), 1323-1330, 2020
152020
Structural basis of the differential binding of engineered knottins to integrins αVβ3 and α5β1
JF Van Agthoven, H Shams, FV Cochran, JL Alonso, JR Kintzing, ...
Structure 27 (9), 1443-1451. e6, 2019
152019
Enhanced intracellular delivery of small molecules and drugs via non-covalent ternary dispersions of single-wall carbon nanotubes
PD Boyer, H Shams, SL Baker, MRK Mofrad, MF Islam, KN Dahl
Journal of materials chemistry B 4 (7), 1324-1330, 2016
142016
Sex-specific Tau methylation patterns and synaptic transcriptional alterations are associated with neural vulnerability during chronic neuroinflammation
A Didonna, E Cantó, H Shams, N Isobe, C Zhao, SJ Caillier, C Condello, ...
Journal of autoimmunity 101, 56-69, 2019
112019
The “stressful” life of cell adhesion molecules: on the mechanosensitivity of integrin adhesome
H Shams, BD Hoffman, MRK Mofrad
Journal of biomechanical engineering 140 (2), 020807, 2018
92018
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