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Aleksandra Bzura
Aleksandra Bzura
Leicester Cancer Research Centre. Department of Genetics and Genome Biology
Verified email at leicester.ac.uk
Title
Cited by
Cited by
Year
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment
M Zhang, JL Luo, Q Sun, J Harber, AG Dawson, A Nakas, S Busacca, ...
Nature communications 12 (1), 1751, 2021
812021
Medical and surgical care of patients with mesothelioma and their relatives carrying germline BAP1 mutations
M Carbone, HI Pass, G Ak, HR Alexander Jr, P Baas, F Baumann, ...
Journal of Thoracic Oncology 17 (7), 873-889, 2022
582022
CD40L/IL-4–stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM
L Lezina, RV Spriggs, D Beck, C Jones, KM Dudek, A Bzura, GDD Jones, ...
Blood advances 2 (15), 1869-1881, 2018
202018
P2. 06-02 mesothelioma stratified therapy (MiST): a phase IIA umbrella trial for accelerating the development of precision medicines
D Fennell, M Hudka, L Darlison, K Lord, A Bzura, J Dzialo, C Pritchard, ...
Journal of Thoracic Oncology 14 (10), S755-S756, 2019
102019
ATM Regulates differentiation of myofibroblastic cancer-associated fibroblasts and can be targeted to overcome immunotherapy resistance
M Mellone, K Piotrowska, G Venturi, L James, A Bzura, MA Lopez, ...
Cancer Research 82 (24), 4571-4585, 2022
92022
Precision therapy for mesothelioma: Feasibility and new opportunities
S Dulloo, A Bzura, DA Fennell
Cancers 13 (10), 2347, 2021
52021
BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms
A Singh, S Busacca, A Gaba, M Sheaff, C Poile, A Nakas, J Dzialo, ...
Oncogene 42 (8), 572-585, 2023
42023
Family Matters: Germline Testing in Thoracic Cancers
F Hathaway, R Martins, S Sorscher, A Bzura, F Dudbridge, DA Fennell
American Society of Clinical Oncology Educational Book 43, e389956, 2023
22023
Accelerating innovations in systemic therapy for pleural mesothelioma
DA Fennell, A Bzura
Nature Cancer 3 (8), 902-904, 2022
22022
61 The first-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 modulates the mesenchymal and immune phenotype in mesothelioma
B Cunniff, T Messier, V Gibson, D Seward, E Baitei, PW Jordan, C Poile, ...
Lung Cancer 190, 107622, 2024
2024
SLC7A11 modulates sensitivity to the first-in-class mitochondrial peroxiredoxin 3 inhibitor thiostrepton (RSO-021) via a ferroptosis independent pathway
T Messier, V Gibson, A Bzura, J Dzialo, C Poile, S Stead, A Saaman, ...
Cancer Research 84 (6_Supplement), 384-384, 2024
2024
First-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 triggers mesenchymal-to-epithelial transition in mesothelioma
T Messier, V Gibson, DJ Seward, EY Baitei, PW Jordan, C Poile, J Dzialo, ...
Cancer Research 84 (6_Supplement), 4716-4716, 2024
2024
ASTX295 engages p53-mediated apoptosis and an inflammatory response in patient derived mesothelioma explants
DA Fennell, J Dzialo, J Rogel, D Faulkner, N Nusrat, A Bzura, K Kutywayo, ...
Cancer Research 84 (6_Supplement), 666-666, 2024
2024
Evaluating niraparib versus active symptom control in patients with previously treated mesothelioma (NERO): a study protocol for a multicentre, randomised, two-arm, open-label …
D Fennell, D Griffiths, Z Eminton, A Morgan-Fox, K Hill, S Ewings, C Stuart, ...
BMJ open 13 (11), e073120, 2023
2023
MA17. 11 Spatial Transformation in Mesothelioma Involves a Hypoxia-TGF Beta-EMT axis that is Reversible via PRX3 Inhibition
M Zhang, T Messier, A Nakas, P Wells-Jordan, C Poile, D Seward, ...
Journal of Thoracic Oncology 18 (11), S165, 2023
2023
P2. 18-02 Successful Generation of Tumor-Infiltrating Lymphocytes (TIL) for Adoptive Cell Therapy from Mesothelioma
DA Fennell, C Poile, A Bzura, J Dzialo, A Nakas, K Kutywayo, A Natarajan, ...
Journal of Thoracic Oncology 18 (11), S381-S382, 2023
2023
A gut microbiota rheostat to forecast response to PDL1-VEGF blockade in mesothelioma.
DA Fennell, A Bzura, A Branson, A King, J Rogel, S Barber, C Poile, ...
Journal of Clinical Oncology 41 (16_suppl), e20534-e20534, 2023
2023
Targeting DNA damage deficient mesotheliomas via synthetic lethal disruption of DNA double-strand repair
A Bzura
University of Leicester, 2023
2023
Protocol: Evaluating niraparib versus active symptom control in patients with previously treated mesothelioma (NERO): a study protocol for a multicentre, randomised, two-arm …
D Fennell, D Griffiths, Z Eminton, A Morgan-Fox, K Hill, S Ewings, C Stuart, ...
BMJ Open 13 (11), 2023
2023
Niraparib efficacy in patients with unresectable mesothelioma: a randomised phase II trial of niraparib versus active symptom control in patients with previously treated …
D Fennell, D Griffiths, Z Eminton, A Morgan-Fox, K Hill, T Nearchou, ...
2023
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