Genetic determinants of cellular addiction to DNA polymerase theta GG Wanjuan Feng, Dennis A. Simpson, Juan Carvajal-Garcia, Brandon A. Price ... Nature Communications, 2019 | 139 | 2019 |
Evidence that the human cell cycle is a series of uncoupled, memoryless phases HX Chao, RI Fakhreddin, HK Shimerov, KM Kedziora, RJ Kumar, J Perez, ... Molecular systems biology 15 (3), e8604, 2019 | 86 | 2019 |
Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4 A Liu, M Chen, R Kumar, M Stefanovic-Racic, RM O’Doherty, Y Ding, ... Nature Communications 9 (1), 708, 2018 | 50 | 2018 |
A P53-independent DNA damage response suppresses oncogenic proliferation and genome instability KD Fagan-Solis, DA Simpson, RJ Kumar, LG Martelotto, LE Mose, ... Cell reports 30 (5), 1385-1399. e7, 2020 | 32 | 2020 |
Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency RJ Kumar, HX Chao, DA Simpson, W Feng, MG Cho, VR Roberts, ... Nucleic Acids Research Cancer 2 (4), zcaa038, 2020 | 21 | 2020 |
Paper or plastic? BCR-ABL1 quantitation and mutation detection from dried blood spots O Sala Torra, L Beppu, JL Smith, L Welden, J Georgievski, K Gupta, ... Blood, The Journal of the American Society of Hematology 127 (22), 2773-2774, 2016 | 18 | 2016 |
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis MG Cho, RJ Kumar, CC Lin, JA Boyer, JA Shahir, K Fagan-Solis, ... Nature, 1-8, 2024 | 11 | 2024 |
Immune-mediated effects of microplanar radiotherapy with a small animal irradiator S Bazyar, ET O’Brien III, T Benefield, VR Roberts, RJ Kumar, GP Gupta, ... Cancers 14 (1), 155, 2021 | 8 | 2021 |
Evidence that the cell cycle is a series of uncoupled, memoryless phases HX Chao, RI Fakhreddin, HK Shimerov, RJ Kumar, GP Gupta, JE Purvis bioRxiv, 283614, 2018 | 7 | 2018 |
Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells RJ Kumar, HX Chao, VR Roberts, AR Sullivan, SJ Shah, DA Simpson, ... BioRxiv, 2020.04. 01.021253, 2020 | 5 | 2020 |
Next-generation tumor-homing induced neural stem cells as an adjuvant to radiation for the treatment of metastatic lung cancer AR Mercer-Smith, A Buckley, A Valdivia, W Jiang, M Thang, N Bell, ... Stem Cell Reviews and Reports 18 (7), 2474-2493, 2022 | 4 | 2022 |
Hyperactive end joining repair mediates radiation resistance in TP53 deficient cells GP Gupta, RJ Kumar, HX Chao, DA Simpson, S Kumar, AS Wozny, ... International Journal of Radiation Oncology, Biology, Physics 108 (3), S41, 2020 | 1 | 2020 |
Abstract A012: Mre11 mediates cGAS activation and tumor suppression through ZBP1-dependent necroptosis in breast cancer M Jo, RJ Kumar, CC Lin, JA Boyer, JA Shahir, K Fagan-Solis, ... Cancer Research 84 (1_Supplement), A012-A012, 2024 | | 2024 |
Mre11 Suppresses Breast Tumorigenesis by Promoting Mitotic Cell Cycle Exit and Activating cGAS-STING Immune Signaling RJ Kumar, M Jo, D Simpson, K Fagan-Solis, HC Xiao, J Purvis, G Gupta ANNALS OF SURGICAL ONCOLOGY 29 (SUPPL 2), 417-418, 2022 | | 2022 |
The DNA Damage Response in TP53 Deficiency RJ Kumar The University of North Carolina at Chapel Hill, 2020 | | 2020 |
Mre11 mediates a p53-independent quiescence program in response to mammary oncogene activation RJ Kumar, HC Xiao, K Fagan-Solis, J Purvis, GP Gupta Cancer Research 79 (4 Supplement), P1-06-05-P1-06-05, 2019 | | 2019 |
Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4 LA Borghesi, A Liu, M Chen, M Stefanovic-Racic, R Kumar, R O’Doherty, ... The Journal of Immunology 200 (1_Supplement), 103.3-103.3, 2018 | | 2018 |
Implementation and Evaluation of Shared Medical Appointments for Type 2 Diabetes at a Free, Student-Run Clinic in Alamance County, NC AR Kahkoska, NF Brazeau, J Largay, RJ Kumar, KA Lynch, MS Kirkman, ... DIABETES 66, A174-A174, 2017 | | 2017 |
Cell-intrinsic TLR4-dependent bone marrow lympho-myeloid distortions in obesity LA Borghesi, A Liu, M Chen, R Kumar, M Stefanovic-Racic, R O’Doherty, ... The Journal of Immunology 198 (1_Supplement), 202.16-202.16, 2017 | | 2017 |
Self-renewing HSCs respond directly to TLR4 ligand and are compromised in obesity, a disease linked to chronic TLR4 stimulation (HEM2P. 270) A Liu, R Kumar, M Stefanovic-Racic, R O'Doherty, Y Ding, L Borghesi The Journal of Immunology 192 (1_Supplement), 50.15-50.15, 2014 | | 2014 |