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Alejandro E Garcia-Flores
Alejandro E Garcia-Flores
Postdoctoral Associate
Verified email at fiu.edu
Title
Cited by
Cited by
Year
Complex interplay between autophagy and oxidative stress in the development of pulmonary disease
W Ornatowski, Q Lu, M Yegambaram, AE Garcia, EA Zemskov, E Maltepe, ...
Redox biology 36, 101679, 2020
2312020
Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics
Q Lu, EA Zemskov, X Sun, H Wang, M Yegambaram, X Wu, ...
Redox Biology 38, 101785, 2021
302021
HER2/HER3 regulates lactate secretion and expression of lactate receptor mRNA through the MAP3K4 associated protein GIT1
AE Garcia-Flores, JJ Sollome, E Thavathiru, JL Bower, RR Vaillancourt
Scientific Reports 9 (1), 10823, 2019
52019
Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission
Q Lu, X Sun, M Yegambaram, W Ornatowski, X Wu, H Wang, ...
Journal of Biological Chemistry 299 (4), 2023
32023
Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics
MD Pokharel, A Garcia-Flores, D Marciano, MC Franco, JR Fineman, ...
Redox Biology, 103049, 2024
22024
Endothelin-1 acutely increases nitric oxide production via the calcineurin mediated dephosphorylation of Caveolin-1
M Yegambaram, S Kumar, X Wu, Q Lu, X Sun, AG Flores, ML Meadows, ...
Nitric Oxide 140, 50-57, 2023
12023
Loss of SOX18/CLAUDIN5 disrupts the pulmonary endothelial barrier in ventilator-induced lung injury
AE Garcia-Flores, CM Gross, EA Zemskov, Q Lu, K Tieu, T Wang, ...
Frontiers in Physiology 13, 1066515, 2022
12022
Ventilator-induced lung injury is associated with endothelial cell mitochondrial fission
M Pokharel, P Fu, A Garcia-Flores, J Soto
2024
Novel Relationship between Mitofusin 2-Mediated Mitochondrial Hyperfusion, Metabolic Remodeling, and Glycolysis in Pulmonary Arterial Endothelial Cells
M Yegambaram, X Sun, AG Flores, Q Lu, J Soto, J Richards, S Aggarwal, ...
International Journal of Molecular Sciences 24 (24), 17533, 2023
2023
Targeting the mitochondrial fission-mediator Drp1 is a potential therapeutic strategy for ventilator induced lung injury
M Pokharel, AG Flores, P Fu, Q Lu, X Sun, T Wang, S Black
FREE RADICAL BIOLOGY AND MEDICINE 208, S94-S94, 2023
2023
Autophagy Plays a Key Role in the Loss of Nitric Oxide Signaling and Endothelial Dysfunction in Pulmonary Vascular Diseases
Y Liang, W Ornatowski, Q Lu, X Sun, AE Garcia, EA Zemskov, E Maltepe, ...
Circulation 146 (Suppl_1), A13625-A13625, 2022
2022
NAMPT induces Mitochondrial and Barrier Dysfunction in Pulmonary Endothelial Cells
M Pokharel, AG Flores, Q Lu, X Sun, T Wang, K Tieu, S Black
Free Radical Biology and Medicine 192, 69, 2022
2022
The anti-apoptotic protein, Survivin induces a shift in endothelial cell in carbon metabolism through a mitochondrial-ROS-dependent increase in HIF-1a signaling
Q Lu, X Sun, J Soto, H Gu, M Yegambaram, AG Flores, E Zemskov, ...
Free Radical Biology and Medicine 192, 65-66, 2022
2022
Mitochondrial Fission Drives A Glycolytic Endothelial Phenotype In Pulmonary Hypertension: Role Of Nitrated RhoA
Q Lu, X Sun, M Yegambaram, W Ornatowski, X Wu, Q Zhang, H Wang, ...
Free Radical Biology and Medicine 180, s49, 2022
2022
Increased Mitochondrial Fission Induces a Warburg Phenotype Via the Hydrogen Peroxide Mediated inhibition of Prolyl Hydroxylase 2 (PHD2) in Pulmonary Arterial Endothelial Cells
X Sun, M Yegambaram, Q Lu, AG Flores, X Wu, T Wang, J Fineman, ...
Free Radical Biology and Medicine 180, s100, 2022
2022
VILI Induced Nitration of RhoA Disrupts Mitochondrial Function Through Increased Generation of Reactive Oxygen Species
AG Flores, Q Lu, X Sun, S Black
Free Radical Biology and Medicine 180, s46, 2022
2022
Autophagy plays a key role in hyper-proliferative phenotype in pulmonary vascular diseases
W Ornatowski, Q Lu, X Sun, AG Flores, A Feng, E Zemskov, E Maltepe, ...
Free Radical Biology and Medicine 180, s52, 2022
2022
Role Of Mitochondrial ROS and HIF Signaling in the Metabolic Reprogramming Associated with Increased Sox18 Expression
M Yegambaram, X Sun, Q Lu, AG Flores, W Ornatowski, V Da Silva, ...
Free Radical Biology and Medicine 180, s56, 2022
2022
The Role of MTK1 in Cell Migration and Extracellular Acidification
AE Garcia Flores
The University of Arizona., 2017
2017
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Articles 1–19