| Promoterless gene targeting without nucleases ameliorates haemophilia B in mice A Barzel, NK Paulk, Y Shi, Y Huang, K Chu, F Zhang, PN Valdmanis, ... Nature 517 (7534), 360-364, 2015 | 278 | 2015 |
| Finding a match: how do homologous sequences get together for recombination? A Barzel, M Kupiec Nature Reviews Genetics 9 (1), 27-37, 2008 | 241 | 2008 |
| Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage AD Nahmad, E Reuveni, E Goldschmidt, T Tenne, M Liberman, ... Nature biotechnology 40 (12), 1807-1813, 2022 | 116 | 2022 |
| Survival advantage of both human hepatocyte xenografts and genome-edited hepatocytes for treatment of α-1 antitrypsin deficiency F Borel, Q Tang, G Gernoux, C Greer, Z Wang, A Barzel, MA Kay, ... Molecular Therapy 25 (11), 2477-2489, 2017 | 73 | 2017 |
| A universal system to select gene-modified hepatocytes in vivo S Nygaard, A Barzel, A Haft, A Major, M Finegold, MA Kay, M Grompe Science translational medicine 8 (342), 342ra79-342ra79, 2016 | 73 | 2016 |
| Promoterless gene targeting without nucleases rescues lethality of a Crigler‐Najjar syndrome mouse model F Porro, G Bortolussi, A Barzel, A De Caneva, A Iaconcig, S Vodret, ... EMBO molecular medicine 9 (10), 1346-1355, 2017 | 71 | 2017 |
| Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion AD Nahmad, Y Raviv, M Horovitz-Fried, I Sofer, T Akriv, D Nataf, I Dotan, ... Nature communications 11 (1), 5851, 2020 | 55 | 2020 |
| Methods and apparatus for nucleic acid synthesis using oligo-templated polymerization MA Kay, A Barzel US Patent App. 14/605,538, 2015 | 51 | 2015 |
| Promoterless, nuclease‐free genome editing confers a growth advantage for corrected hepatocytes in mice with methylmalonic acidemia RJ Chandler, LE Venturoni, J Liao, BT Hubbard, JL Schneller, ... Hepatology 73 (6), 2223-2237, 2021 | 47 | 2021 |
| Coupling AAV-mediated promoterless gene targeting to SaCas9 nuclease to efficiently correct liver metabolic diseases A De Caneva, F Porro, G Bortolussi, R Sola, M Lisjak, A Barzel, M Giacca, ... JCI insight 4 (15), 2019 | 46 | 2019 |
| Native homing endonucleases can target conserved genes in humans and in animal models A Barzel, E Privman, M Peeri, A Naor, E Shachar, D Burstein, R Lazary, ... Nucleic acids research 39 (15), 6646-6659, 2011 | 40 | 2011 |
| In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice AD Nahmad, CR Lazzarotto, N Zelikson, T Kustin, M Tenuta, D Huang, ... Nature biotechnology 40 (8), 1241-1249, 2022 | 38 | 2022 |
| Homing endonucleases residing within inteins: evolutionary puzzles awaiting genetic solutions A Barzel, A Naor, E Privman, M Kupiec, U Gophna Biochemical Society Transactions 39 (1), 169-173, 2011 | 36 | 2011 |
| Non-disruptive gene targeting MA Kay, M Porteus, J Barker, J Checketts, R Voit, A Barzel US Patent App. 13/838,927, 2013 | 33 | 2013 |
| Home and away-the evolutionary dynamics of homing endonucleases A Barzel, U Obolski, JP Gogarten, M Kupiec, L Hadany BMC Evolutionary Biology 11, 1-14, 2011 | 29 | 2011 |
| In vivo characterization of the homing endonuclease within the polB gene in the halophilic archaeon Haloferax volcanii A Naor, R Lazary, A Barzel, RT Papke, U Gophna PLoS One 6 (1), e15833, 2011 | 20 | 2011 |
| Antibody repertoire analysis of tumor-infiltrating B cells reveals distinct signatures and distributions across tissues L Aizik, Y Dror, D Taussig, A Barzel, Y Carmi, Y Wine Frontiers in Immunology 12, 705381, 2021 | 17 | 2021 |
| MCP-1/CCR2 axis inhibition sensitizes the brain microenvironment against melanoma brain metastasis progression S Pozzi, A Scomparin, D Ben-Shushan, E Yeini, P Ofek, AD Nahmad, ... JCI insight 7 (17), 2022 | 12 | 2022 |
| Promoterless Gene Targeting Approach Combined to CRISPR/Cas9 Efficiently Corrects Hemophilia B Phenotype in Neonatal Mice M Lisjak, A De Caneva, T Marais, E Barbon, MG Biferi, F Porro, A Barzel, ... Frontiers in Genome Editing 4, 785698, 2022 | 9 | 2022 |
| In vivo engineered B cells retain memory and secrete high titers of anti-HIV antibodies in mice AD Nahmad, CR Lazzarotto, N Zelikson, T Kustin, M Tenuta, D Huang, ... bioRxiv, 2021.04. 08.438900, 2021 | 4 | 2021 |
