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Mark Ranek
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Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease
DI Lee, G Zhu, T Sasaki, GS Cho, N Hamdani, R Holewinski, SH Jo, ...
Nature 519 (7544), 472-476, 2015
3392015
Autophagy and p62 in cardiac proteinopathy
Q Zheng, H Su, MJ Ranek, X Wang
Circulation research 109 (3), 296-308, 2011
1982011
Protein quality control and degradation in cardiomyocytes
X Wang, H Su, MJ Ranek
Journal of molecular and cellular cardiology 45 (1), 11-27, 2008
1322008
Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins
MJ Ranek, EJM Terpstra, J Li, DA Kass, X Wang
Circulation 128 (4), 365-376, 2013
1192013
COP9 signalosome regulates autophagosome maturation
H Su, F Li, MJ Ranek, N Wei, X Wang
Circulation 124 (19), 2117-2128, 2011
1192011
The role of heat shock proteins and co-chaperones in heart failure
MJ Ranek, MJ Stachowski, JA Kirk, MS Willis
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
1172018
Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction
A Ngkelo, A Richart, JA Kirk, P Bonnin, J Vilar, M Lemitre, P Marck, ...
Journal of Experimental Medicine 213 (7), 1353-1374, 2016
1172016
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease
BL Lin, D Matera, JF Doerner, N Zheng, D Del Camino, S Mishra, H Bian, ...
Proceedings of the National Academy of Sciences 116 (20), 10156-10161, 2019
1092019
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress
MJ Ranek, KM Kokkonen-Simon, A Chen, BL Dunkerly-Eyring, MP Vera, ...
Nature 566 (7743), 264-269, 2019
1062019
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis
QJ Zhang, TAT Tran, M Wang, MJ Ranek, KM Kokkonen-Simon, J Gao, ...
Nature communications 9 (1), 5230, 2018
872018
Prevention of PKG1α oxidation augments cardioprotection in the stressed heart
T Nakamura, MJ Ranek, DI Lee, VS Hahn, C Kim, P Eaton, DA Kass
The Journal of clinical investigation 125 (6), 2468-2472, 2015
772015
Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy
MJ Ranek, X Wang
Current hypertension reports 11 (6), 389-395, 2009
702009
Functional amyloid signaling via the inflammasome, necrosome, and signalosome: new therapeutic targets in heart failure
TL Parry, JH Melehani, MJ Ranek, MS Willis
Frontiers in Cardiovascular Medicine 2, 25, 2015
492015
The pathophysiology of cardiac hypertrophy and heart failure
WE Stansfield, M Ranek, A Pendse, JC Schisler, S Wang, T Pulinilkunnil, ...
Cellular and molecular pathobiology of cardiovascular disease, 51-78, 2014
462014
Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State
SB Wang, V Venkatraman, EL Crowgey, T Liu, Z Fu, R Holewinski, ...
Circulation research 122 (11), 1517-1531, 2018
442018
Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse
G Zhu, D Groneberg, G Sikka, D Hori, MJ Ranek, T Nakamura, E Takimoto, ...
Hypertension 65 (2), 385-392, 2015
422015
Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload
MJ Ranek, H Zheng, W Huang, AR Kumarapeli, J Li, J Liu, X Wang
Journal of molecular and cellular cardiology 85, 273-281, 2015
392015
MTORC1-regulated metabolism controlled by TSC2 limits cardiac reperfusion injury
CU Oeing, S Jun, S Mishra, BL Dunkerly-Eyring, A Chen, MI Grajeda, ...
Circulation research 128 (5), 639-651, 2021
312021
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury
MJ Ranek, C Oeing, R Sanchez-Hodge, KM Kokkonen-Simon, D Dillard, ...
Nature communications 11 (1), 5237, 2020
312020
PKG1α cysteine-42 redox state controls mTORC1 activation in pathological cardiac hypertrophy
CU Oeing, T Nakamura, S Pan, S Mishra, BL Dunkerly-Eyring, ...
Circulation research 127 (4), 522-533, 2020
302020
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