Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload Z Ma, N Huebsch, S Koo, MA Mandegar, B Siemons, S Boggess, ... Nature biomedical engineering 2 (12), 955-967, 2018 | 100 | 2018 |
Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips N Huebsch, B Charrez, G Neiman, B Siemons, SC Boggess, S Wall, ... Nature biomedical engineering 6 (4), 372-388, 2022 | 49 | 2022 |
Isochoric supercooled preservation and revival of human cardiac microtissues MJ Powell-Palm, V Charwat, B Charrez, B Siemons, KE Healy, ... Communications biology 4 (1), 1118, 2021 | 30 | 2021 |
Integrated isogenic human induced pluripotent stem cell–based liver and heart microphysiological systems predict unsafe drug–drug interaction FT Lee-Montiel, A Laemmle, V Charwat, L Dumont, CS Lee, N Huebsch, ... Frontiers in pharmacology 12, 667010, 2021 | 29 | 2021 |
New molecular scaffolds for fluorescent voltage indicators SC Boggess, SS Gandhi, BA Siemons, N Huebsch, KE Healy, EW Miller ACS chemical biology 14 (3), 390-396, 2019 | 26 | 2019 |
Heart muscle microphysiological system for cardiac liability prediction of repurposed COVID-19 therapeutics B Charrez, V Charwat, BA Siemons, I Goswami, C Sakolish, YS Luo, ... Frontiers in Pharmacology 12, 684252, 2021 | 15 | 2021 |
Metabolically-driven maturation of hiPSC-cell derived cardiac chip N Huebsch, B Charrez, B Siemons, SC Boggess, S Wall, G Neiman, ... bioRxiv, 485169, 2018 | 15 | 2018 |
In vitro safety “clinical trial” of the cardiac liability of drug polytherapy B Charrez, V Charwat, B Siemons, H Finsberg, EW Miller, AG Edwards, ... Clinical and translational science 14 (3), 1155-1165, 2021 | 12 | 2021 |
Integrated hiPSC-based liver and heart microphysiological systems predict unsafe drug-drug interaction FT Lee-Montiel, A Laemmle, L Dumont, CS Lee, N Huebsch, V Charwat, ... BioRxiv, 2020.05. 24.112771, 2020 | 9 | 2020 |
Quantitatively characterizing drug‐induced arrhythmic contractile motions of human stem cell‐derived cardiomyocytes P Hoang, N Huebsch, SH Bang, BA Siemons, BR Conklin, KE Healy, ... Biotechnology and bioengineering 115 (8), 1958-1970, 2018 | 8 | 2018 |
Validating the arrhythmogenic potential of high-, intermediate-, and low-risk drugs in a human-induced pluripotent stem cell-derived cardiac microphysiological system V Charwat, B Charrez, BA Siemons, H Finsberg, KH Jæger, AG Edwards, ... ACS pharmacology & translational science 5 (8), 652-667, 2022 | 6 | 2022 |
In vitro safety “clinical trial” of the cardiac liability of hydroxychloroquine and azithromycin as COVID19 polytherapy B Charrez, V Charwat, B Siemons, H Finsberg, E Miller, AG Edwards, ... bioRxiv, 2020.12. 21.423869, 2020 | 1 | 2020 |