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Sumera Perveen
Sumera Perveen
Verified email at utoronto.ca - Homepage
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Cited by
Year
The structure-based design of SARS-CoV-2 nsp14 methyltransferase ligands yields nanomolar inhibitors
T Otava, M Sala, F Li, J Fanfrlik, K Devkota, S Perveen, I Chau, P Pakarian, ...
ACS infectious diseases 7 (8), 2214-2220, 2021
672021
Probing the SAM binding site of SARS-CoV-2 Nsp14 in vitro using SAM competitive inhibitors guides developing selective bisubstrate inhibitors
K Devkota, M Schapira, S Perveen, A Khalili Yazdi, F Li, I Chau, P Ghiabi, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (9), 1200-1211, 2021
642021
A high-throughput RNA displacement assay for screening SARS-CoV-2 nsp10-nsp16 complex toward developing therapeutics for COVID-19
S Perveen, A Khalili Yazdi, K Devkota, F Li, P Ghiabi, T Hajian, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (5), 620-627, 2021
282021
A high-throughput radioactivity-based assay for screening SARS-CoV-2 nsp10-nsp16 complex
A Khalili Yazdi, F Li, K Devkota, S Perveen, P Ghiabi, T Hajian, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (6), 757-765, 2021
222021
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses
F Li, P Ghiabi, T Hajian, M Klima, ASM Li, AK Yazdi, I Chau, P Loppnau, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1867 (4), 130319, 2023
132023
Anthranilate phosphoribosyltransferase from the hyperthermophilic archaeon Thermococcus kodakarensis shows maximum activity with zinc and forms a unique …
S Perveen, N Rashid, XF Tang, T Imanaka, AC Papageorgiou
FEBS Open bio 7 (8), 1217-1230, 2017
132017
Kinetic characterization of SARS-CoV-2 nsp13 ATPase activity and discovery of small-molecule inhibitors
AK Yazdi, P Pakarian, S Perveen, T Hajian, V Santhakumar, A Bolotokova, ...
ACS Infectious Diseases 8 (8), 1533-1542, 2022
92022
Pcal_1127, a highly stable and efficient ribose-5-phosphate pyrophosphokinase from Pyrobaculum calidifontis
T Bibi, S Perveen, I Aziz, Q Bashir, N Rashid, T Imanaka, M Akhtar
Extremophiles 20, 821-830, 2016
92016
Extremely stable indole-3-glycerol-phosphate synthase from hyperthermophilic archaeon Pyrococcus furiosus
M Arif, N Rashid, S Perveen, Q Bashir, M Akhtar
Extremophiles 23, 69-77, 2019
82019
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
AK Yazdi, S Perveen, C Dong, X Song, A Dong, MM Szewczyk, ...
RSC Medicinal Chemistry 15 (3), 1066-1071, 2024
32024
Probing the mechanism of Cbl-b inhibition by a small-molecule inhibitor
S Kimani, S Perveen, M Szewezyk, H Zeng, A Dong, F Li, P Ghiabi, Y Li, ...
bioRxiv, 2023.05. 05.539612, 2023
32023
Crystal structure of a phosphoribosyl anthranilate isomerase from the hyperthermophilic archaeon Thermococcus kodakaraensis
S Perveen, N Rashid, AC Papageorgiou
Acta Crystallographica Section F: Structural Biology Communications 72 (11 …, 2016
32016
Development of Complementary Photo‐arginine/lysine to Promote Discovery of Arg/Lys Hptms Interactomes
Y Zong, N Weiss, K Wang, AE Pagano, S Heissel, S Perveen, J Huang
Advanced Science, 2307526, 2024
12024
The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition
SW Kimani, S Perveen, M Szewezyk, H Zeng, A Dong, F Li, P Ghiabi, Y Li, ...
Communications Biology 6 (1), 1272, 2023
12023
Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)
S Perveen, CA Zepeda-Velázquez, D McLeod, R Marcellus, ...
bioRxiv, 2022.01. 05.475077, 2022
12022
Development of Peptide Displacement Assays to Screen for Antagonists of DDB1 Interactions
D Yong, S Ahmad, MF Mabanglo, L Halabelian, M Schapira, S Ackloo, ...
Biochemistry, 2024
2024
Kinetic characterization of human mRNA guanine-N7 methyltransferase
S Perveen, AK Yazdi, T Hajian, F Li, M Vedadi
Scientific Reports 14 (1), 4509, 2024
2024
Application of Established Computational Techniques to Identify Potential SARS-CoV-2 Nsp14-MTase Inhibitors in Low Data Regimes
AK Nigam, MFD Hurley, F Lu, E Konkoľová, M Klima, J Trylčová, R Pollice, ...
Digital Discovery, 2024
2024
A resource to enable chemical biology and drug discovery of WDR Proteins
CH Arrowsmith, S Ackloo, F Li, M Szewczyk, A Seitova, P Loppnau, ...
bioRxiv, 2024.03. 03.583197, 2024
2024
Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors
AK Nigam, MFD Hurley, F Li, E Konkoľová, M Klíma, J Trylčová, R Pollice, ...
bioRxiv, 2023
2023
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