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David Todd Melnekoff
David Todd Melnekoff
Icahn School of Medicine at Mt. Sinai
Verified email at columbia.edu
Title
Cited by
Cited by
Year
A new method for vitrifying samples for cryoEM
I Razinkov, VP Dandey, H Wei, Z Zhang, D Melnekoff, WJ Rice, C Wigge, ...
Journal of structural biology 195 (2), 190-198, 2016
1412016
Mutation-derived neoantigen-specific T-cell responses in multiple myeloma
D Perumal, N Imai, A Laganà, J Finnigan, D Melnekoff, VV Leshchenko, ...
Clinical Cancer Research 26 (2), 450-464, 2020
782020
Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma
A Laganà, D Perumal, D Melnekoff, B Readhead, BA Kidd, V Leshchenko, ...
Leukemia 32 (1), 120-130, 2018
702018
Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications
S Bhalla, DT Melnekoff, A Aleman, V Leshchenko, P Restrepo, J Keats, ...
Science Advances 7 (47), eabg9551, 2021
642021
Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy
O Van Oekelen, K Nath, TH Mouhieddine, T Farzana, A Aleman, ...
Blood 141 (7), 756-765, 2023
492023
Precision medicine for relapsed multiple myeloma on the basis of an integrative multiomics approach
A Laganà, I Beno, D Melnekoff, V Leshchenko, D Madduri, D Ramdas, ...
JCO precision oncology 2, 1-17, 2018
362018
Sequencing T-cell redirection therapies leads to deep and durable responses in patients with relapsed/refractory myeloma
TH Mouhieddine, O Van Oekelen, DT Melnekoff, J Li, Y Ghodke-Puranik, ...
Blood advances 7 (6), 1056-1064, 2023
242023
A phase II study of pomalidomide, daily oral cyclophosphamide, and dexamethasone in relapsed/refractory multiple myeloma
O Van Oekelen, S Parekh, HJ Cho, N Vishnuvardhan, D Madduri, ...
Leukemia & lymphoma 61 (9), 2208-2215, 2020
152020
A three-gene signature predicts response to selinexor in multiple myeloma
P Restrepo, S Bhalla, Y Ghodke-Puranik, A Aleman, V Leshchenko, ...
JCO Precision Oncology 6, e2200147, 2022
132022
Single-cell sequencing technologies in precision oncology
DT Melnekoff, A Laganà
Computational Methods for Precision Oncology, 269-282, 2022
112022
Single-cell profiling reveals contribution of tumor extrinsic and intrinsic factors to BCMA-targeted CAR-T cell efficacy in multiple myeloma
DT Melnekoff, Y Ghodke-Puranik, O Van Oekelen, A Aleman, ...
Blood 138, 326, 2021
62021
Clinical outcomes and treatment strategies for relapsed/refractory myeloma patients after relapse on BCMA-targeted CAR T
O Van Oekelen, TH Mouhieddine, D Pan, M Metzger, S Agte, A Aleman, ...
Blood 138, 2704, 2021
62021
ADAR1 can drive Multiple Myeloma progression by acting both as an RNA editor of specific transcripts and as a DNA mutator of their cognate genes
RN Tasakis, A Laganà, D Stamkopoulou, DT Melnekoff, P Nedumaran, ...
Biorxiv, 2020.02. 11.943845, 2020
62020
E2F1 is a biomarker of selinexor resistance in relapsed/refractory multiple myeloma patients
A Lagana, S Park, D Edwards, V Leshchenko, M Crochiere, Y Landesman, ...
Blood 132, 3216, 2018
62018
Triple MAPK inhibition salvaged a relapsed post-BCMA CAR-T cell therapy multiple myeloma patient with a BRAF V600E subclonal mutation
M Elnaggar, S Agte, P Restrepo, M Ram, D Melnekoff, C Adamopoulos, ...
Journal of Hematology & Oncology 15 (1), 109, 2022
52022
Increased HLA-E expression correlates with early relapse in multiple myeloma
A Lagana, DF Ruan, D Melnekoff, V Leshchenko, D Perumal, A Rahman, ...
Blood 132, 59, 2018
52018
Clonal evolution in newly diagnosed multiple myeloma patients: a follow-up study from the Mmrf Commpass Genomics Project
A Lagana, D Melnekoff, I Beno, V Leshchenko, D Perumal, JJ Keats, ...
Blood 130, 325, 2017
42017
Network modeling reveals CDC42BPA and CLEC11A as novel driver genes of t (4; 14) multiple myeloma
D Perumal, D Melnekoff, B Readhead, B Kidd, VV Leshchenko, PY Kuo, ...
Blood 128 (22), 802, 2016
32016
Pathogenic germline variants in multiple myeloma
S Thibaud, A Etra, R Subaran, Z Soens, S Newman, R Chen, A Chari, ...
Blood 138, 399, 2021
22021
Clinical outcomes of relapsed/refractory multiple myeloma patients following treatment with bispecific antibodies (BiAbs)
TH Mouhieddine, O Van Oekelen, D Pan, S Agte, A Aleman, DT Melnekoff, ...
Blood 138, 821, 2021
22021
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