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Gregory Takacs
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Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy
GP Takacs, JA Flores-Toro, JK Harrison
Pharmacology & therapeutics 222, 107790, 2021
342021
Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner
GP Takacs, CJ Kreiger, D Luo, G Tian, JS Garcia, LP Deleyrolle, ...
Frontiers in Immunology 13, 993444, 2023
152023
Functional dependency analysis identifies potential druggable targets in acute myeloid leukemia
Y Zhou, GP Takacs, JK Lamba, C Vulpe, CR Cogle
Cancers 12 (12), 3710, 2020
82020
Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+ myeloid cells into the tumor microenvironment in a redundant manner
GP Takacs, CJ Kreiger, D Luo, G Tian, JS Garcia, LP Deleyrolle, ...
bioRxiv, 2022.07. 08.499173, 2022
22022
CRISPR Dropout Screens Identify DHODH,PIK3C3, and Crkl as Potential Therapeutic Targets in Acute Myeloid Leukemia
G Takacs, Y Zhou, DJ King, A Meacham, L Alex, A Tagmount, A Sobh, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
22019
Global stability and parameter analysis reinforce therapeutic targets of PD-L1-PD-1 and MDSCs for glioblastoma
HG Anderson, GP Takacs, DC Harris, Y Kuang, JK Harrison, TL Stepien
Journal of Mathematical Biology 88 (1), 10, 2024
12024
TMIC-32. TUMOR CELL CILIA ASSOCIATE WITH SPECIFIC IMMUNE CELL POPULATIONS IN HUMAN AND MOUSE MODELS OF GBM
L Deleyrolle, J Harrison, G Takacs, M Sarkisian
Neuro-Oncology 24 (Supplement_7), vii278-vii278, 2022
12022
Method to identify silent codon mutations that may alter peptide elongation kinetics and co-translational protein folding
R Worthington, E Ball, B Wolf, G Takacs
Proteomics for Drug Discovery: Methods and Protocols, 237-243, 2017
12017
Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8+ T cells in a NOS-dependent manner
GP Takacs, JS Garcia, CA Hodges, CJ Kreiger, A Sherman, JK Harrison
bioRxiv, 2024.06. 05.597474, 2024
2024
Optimal control of combination immunotherapy in a glioblastoma-immune dynamics model
HG Anderson, GP Takacs, JK Harrison, L Rong, TL Stepien
bioRxiv, 2024.04. 29.591725, 2024
2024
DR5 disulfide bonding as a sensor and effector of protein folding stress
ME Law, ZM Dulloo, SR Eggleston, GP Takacs, GM Alexandrow, M Wang, ...
bioRxiv, 2024.03. 04.583390, 2024
2024
Systemically targeting monocytic MDSCs using dendrimers and their cell-level biodistribution kinetics
CA Littrell, GP Takacs, C Siva Sankara, A Sherman, KA Rubach, ...
bioRxiv, 2024.02. 14.580395, 2024
2024
CD4 T CELLS MEDIATED UPREGULATION OF CCL4 CHEMOKINE DRIVES GLIOBLASTOMA TUMOR MICROENVIRONMENT REPROGRAMMING FOLLOWING TREATMENT WITH A NOVEL MRNA VACCINE
A Chauhan, G Ebrahim, F Dastmalchi, K McGrath, N Thomas, GP Takacs, ...
NEURO-ONCOLOGY 25, 2023
2023
987 Glioma-derived factors induce an immune suppressive phenotype in bone marrow-derived CCR2+ myeloid cells
G Takacs, J Garcia, A Sherman, C Kreiger, D Luo, J Harrison
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
IMMU-21. GLIOMA-DERIVED FACTORS RECRUIT AND INDUCE AN IMMUNE SUPPRESSIVE PHENOTYPE IN BONE MARROW-DERIVED CCR2+ MYELOID …
G Takacs, C Kreiger, D Luo, G Tian, L Deleyrolle, J Harrison
Neuro-Oncology 24 (Supplement_7), vii135-vii136, 2022
2022
A CTS Team Approach to Modeling Migration and Suppression of CCR2+/CX3CR1+ Myeloid Cells in Glioblastoma
H Anderson, GP Takacs, C Kreiger, D Luo, L Rong, JK Harrison, ...
2022
IMMU-05. CCR2+ MYELOID-DERIVED SUPPRESSOR CELLS FROM MURINE GLIOMAS ARE SOURCED FROM THE BONE MARROW, SUPPRESS T CELL …
G Takacs, C Kreiger, D Luo, J Flores-Toro, L Deleyrolle, M Rahman, ...
Neuro-Oncology 23 (Supplement_6), vi92-vi93, 2021
2021
84357 A TL1 Team Approach to Integrating Mathematical and Biological Models to Target Myeloid-Derived Immune Cells in Glioblastoma
GP Takacs, H Anderson, C Kreiger, D Luo, L Rong, T Stepien, ...
Journal of Clinical and Translational Science 5 (s1), 20-20, 2021
2021
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