New developments in dry powder pulmonary vaccine delivery T Sou, EN Meeusen, M de Veer, DAV Morton, LM Kaminskas, ... Trends in biotechnology 29 (4), 191-198, 2011 | 165 | 2011 |
The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules T Sou, LM Kaminskas, TH Nguyen, R Carlberg, MP McIntosh, DAV Morton European Journal of Pharmaceutics and Biopharmaceutics 83 (2), 234-243, 2013 | 155 | 2013 |
Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: a design of experiment approach T Sou, L Orlando, MP McIntosh, LM Kaminskas, DAV Morton International journal of pharmaceutics 421 (2), 220-229, 2011 | 71 | 2011 |
Spray-dried influenza antigen with trehalose and leucine produces an aerosolizable powder vaccine formulation that induces strong systemic and mucosal immunity after pulmonary … T Sou, DAV Morton, M Williamson, EN Meeusen, LM Kaminskas, ... Journal of aerosol medicine and pulmonary drug delivery 28 (5), 361-371, 2015 | 57 | 2015 |
Automated assays for thermodynamic (equilibrium) solubility determination T Sou, CAS Bergström Drug Discovery Today: Technologies 27, 11-19, 2018 | 53 | 2018 |
Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa F Soukarieh, R Liu, M Romero, SN Roberston, W Richardson, S Lucanto, ... Frontiers in Chemistry 8, 204, 2020 | 41 | 2020 |
Contemporary formulation development for inhaled pharmaceuticals T Sou, CAS Bergström Journal of Pharmaceutical Sciences 110 (1), 66-86, 2021 | 38 | 2021 |
Model‐informed drug development for antimicrobials: translational PK and PK/PD modeling to predict an efficacious human dose for apramycin T Sou, J Hansen, E Liepinsh, M Backlund, O Ercan, S Grinberga, S Cao, ... Clinical Pharmacology & Therapeutics 109 (4), 1063-1073, 2021 | 28 | 2021 |
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa F Soukarieh, A Mashabi, W Richardson, EV Oton, M Romero, ... ACS Infectious Diseases 7 (9), 2666-2685, 2021 | 26 | 2021 |
Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy M Bue, T Sou, ASL Okkels, P Hanberg, A Thorsted, LE Friberg, ... International Journal of Infectious Diseases 92, 133-140, 2020 | 26 | 2020 |
Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer … T Sou, RT Forbes, J Gray, RJ Prankerd, LM Kaminskas, MP McIntosh, ... Powder technology 287, 248-255, 2016 | 25 | 2016 |
Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: the effect of polymers on the formation of an amorphous matrix for … T Sou, MP McIntosh, LM Kaminskas, RJ Prankerd, DAV Morton Drying technology 31 (13-14), 1451-1458, 2013 | 20 | 2013 |
Model-based drug development in pulmonary delivery: pharmacokinetic analysis of novel drug candidates for treatment of Pseudomonas aeruginosa lung infection T Sou, I Kukavica-Ibrulj, F Soukarieh, N Halliday, RC Levesque, ... Journal of Pharmaceutical Sciences 108 (1), 630-640, 2019 | 18 | 2019 |
Model-informed drug development in pulmonary delivery: semimechanistic pharmacokinetic–pharmacodynamic modeling for evaluation of treatments against chronic Pseudomonas … T Sou, I Kukavica-Ibrulj, RC Levesque, LE Friberg, CAS Bergström Molecular Pharmaceutics 17 (5), 1458-1469, 2020 | 10 | 2020 |
Pulmonary and systemic pharmacokinetics of colistin methanesulfonate (CMS) and formed colistin following nebulisation of CMS among patients with ventilator-associated pneumonia A Gkoufa, T Sou, I Karaiskos, C Routsi, YW Lin, M Psichogiou, ... International Journal of Antimicrobial Agents 59 (6), 106588, 2022 | 8 | 2022 |
Model-informed drug discovery and development in pulmonary delivery: biopharmaceutical Pharmacometric Modeling for formulation evaluation of pulmonary suspensions T Sou, F Soukarieh, P Williams, MJ Stocks, M Cámara, CAS Bergström ACS omega 5 (40), 25733-25746, 2020 | 6 | 2020 |
Method and formulation for inhalation M McIntosh, D Morton, T Sou, L Olerile, R Prankerd US Patent 11,065,297, 2021 | 2 | 2021 |
Method and formulation for inhalation M McIntosh, D Morton, T Sou, L Olerile, R Prankerd US Patent App. 14/236,465, 2014 | 1 | 2014 |
The role and interaction effects of amino acids on the particle engineering of a mannitol-based powder formulation DAV Morton, T Sou, LM Kaminskas, MP McIntosh, L Orlando The electronic conference on pharmaceutical sciences ECPS, 1-6, 2011 | 1 | 2011 |
Investigating effects of surface modifications on a mannitol dry powder inhaler plume by laser diffraction DAV Morton, MP McIntosh, T Sou Respiratory Drug Delivery 2008, 649-653, 2008 | 1 | 2008 |