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Yi Miao
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Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli
C Pleguezuelos-Manzano, J Puschhof, AR Huber, A van Hoeck, ...
Nature 580 (7802), 269-273, 2020
7232020
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes
JW Buikema, S Lee, WR Goodyer, RG Maas, O Chirikian, G Li, Y Miao, ...
Cell Stem Cell 27 (1), 50-63. e5, 2020
1462020
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ...
Science 364 (6442), eaav7532, 2019
1092019
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ...
Cell Stem Cell 27 (5), 840-851, 2020
952020
Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China
Y Wu, Z Lou, Y Miao, Y Yu, H Dong, W Peng, M Bartlam, X Li, Z Rao
Protein & cell 1, 491-500, 2010
912010
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
N Tsutsumi, S Mukherjee, D Waghray, CY Janda, KM Jude, Y Miao, ...
eLife 9, e58464, 2020
832020
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability
M Vallon, K Yuki, TD Nguyen, J Chang, J Yuan, D Siepe, Y Miao, M Essler, ...
Cell Reports 25 (2), 339-349. e9, 2018
792018
Trehalose pathway as an antifungal target
JR Perfect, JL Tenor, Y Miao, RG Brennan
Virulence 8 (2), 143-149, 2017
712017
Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis
Y Miao, JL Tenor, DL Toffaletti, EJ Washington, J Liu, WR Shadrick, ...
Proceedings of the National Academy of Sciences 113 (26), 7148-7153, 2016
542016
RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development
J Wang*, Y Miao*, R Wicklein, Z Sun, J Wang, KM Jude, RA Fernandes, ...
Cell 184 (24), 5869-5885, 2021
522021
Receptor subtype discrimination using extensive shape complementary designed interfaces
LT Dang*, Y Miao*, A Ha, K Yuki, K Park, CY Janda, KM Jude, K Mohan, ...
Nature structural & molecular biology 26 (6), 407, 2019
382019
Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for …
Y Miao, JL Tenor, DL Toffaletti, SA Maskarinec, J Liu, RE Lee, JR Perfect, ...
mBio 8 (4), e00643-17, 2017
332017
Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling
M Maimets, MT Pedersen, J Guiu, J Dreier, M Thodberg, Y Antoku, ...
Nature Communications 13 (1), 1-12, 2022
272022
RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer
OM Gbenedio, C Bonnans, D Grun, CY Wang, AJ Hatch, MR Mahoney, ...
JCI insight 4 (15), 2019
232019
Surrogate R-spondins for tissue-specific potentiation of Wnt signaling
VC Luca*, Y Miao*, X Li, MJ Hollander, CJ Kuo, KC Garcia
PloS one 15 (1), 2020
182020
Structure of the Wnt–Frizzled–LRP6 initiation complex reveals the basis for coreceptor discrimination
N Tsutsumi, S Hwang, D Waghray, S Hansen, KM Jude, N Wang, Y Miao, ...
Proceedings of the National Academy of Sciences 120 (11), e2218238120, 2023
122023
Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry
QC Yu, A Geng, CB Preusch, Y Chen, G Peng, Y Xu, Y Jia, Y Miao, H Xue, ...
Cell Reports 41 (8), 2022
42022
Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co‐Condensation of Wnt Signalodroplets
M Philippi, CP Richter, M Kappen, I Watrinet, Y Miao, M Runge, L Jorde, ...
Small 18 (50), 2203723, 2022
22022
TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple endogenous signaling pathways
NS Funa, KH de Lichtenberg, MS Hansen, J van Cuyl Kuylenstierna, ...
bioRxiv, 2021
12021
Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development
A Samocha, HM Doh, V Sitarama, QH Nguyen, O Gbenedio, JD Rudolf, ...
bioRxiv, 2020
12020
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