Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli C Pleguezuelos-Manzano, J Puschhof, AR Huber, A van Hoeck, ... Nature 580 (7802), 269-273, 2020 | 723 | 2020 |
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes JW Buikema, S Lee, WR Goodyer, RG Maas, O Chirikian, G Li, Y Miao, ... Cell Stem Cell 27 (1), 50-63. e5, 2020 | 146 | 2020 |
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ... Science 364 (6442), eaav7532, 2019 | 109 | 2019 |
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ... Cell Stem Cell 27 (5), 840-851, 2020 | 95 | 2020 |
Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China Y Wu, Z Lou, Y Miao, Y Yu, H Dong, W Peng, M Bartlam, X Li, Z Rao Protein & cell 1, 491-500, 2010 | 91 | 2010 |
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling N Tsutsumi, S Mukherjee, D Waghray, CY Janda, KM Jude, Y Miao, ... eLife 9, e58464, 2020 | 83 | 2020 |
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability M Vallon, K Yuki, TD Nguyen, J Chang, J Yuan, D Siepe, Y Miao, M Essler, ... Cell Reports 25 (2), 339-349. e9, 2018 | 79 | 2018 |
Trehalose pathway as an antifungal target JR Perfect, JL Tenor, Y Miao, RG Brennan Virulence 8 (2), 143-149, 2017 | 71 | 2017 |
Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis Y Miao, JL Tenor, DL Toffaletti, EJ Washington, J Liu, WR Shadrick, ... Proceedings of the National Academy of Sciences 113 (26), 7148-7153, 2016 | 54 | 2016 |
RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development J Wang*, Y Miao*, R Wicklein, Z Sun, J Wang, KM Jude, RA Fernandes, ... Cell 184 (24), 5869-5885, 2021 | 52 | 2021 |
Receptor subtype discrimination using extensive shape complementary designed interfaces LT Dang*, Y Miao*, A Ha, K Yuki, K Park, CY Janda, KM Jude, K Mohan, ... Nature structural & molecular biology 26 (6), 407, 2019 | 38 | 2019 |
Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for … Y Miao, JL Tenor, DL Toffaletti, SA Maskarinec, J Liu, RE Lee, JR Perfect, ... mBio 8 (4), e00643-17, 2017 | 33 | 2017 |
Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling M Maimets, MT Pedersen, J Guiu, J Dreier, M Thodberg, Y Antoku, ... Nature Communications 13 (1), 1-12, 2022 | 27 | 2022 |
RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer OM Gbenedio, C Bonnans, D Grun, CY Wang, AJ Hatch, MR Mahoney, ... JCI insight 4 (15), 2019 | 23 | 2019 |
Surrogate R-spondins for tissue-specific potentiation of Wnt signaling VC Luca*, Y Miao*, X Li, MJ Hollander, CJ Kuo, KC Garcia PloS one 15 (1), 2020 | 18 | 2020 |
Structure of the Wnt–Frizzled–LRP6 initiation complex reveals the basis for coreceptor discrimination N Tsutsumi, S Hwang, D Waghray, S Hansen, KM Jude, N Wang, Y Miao, ... Proceedings of the National Academy of Sciences 120 (11), e2218238120, 2023 | 12 | 2023 |
Activation of Wnt/β-catenin signaling by Zeb1 in endothelial progenitors induces vascular quiescence entry QC Yu, A Geng, CB Preusch, Y Chen, G Peng, Y Xu, Y Jia, Y Miao, H Xue, ... Cell Reports 41 (8), 2022 | 4 | 2022 |
Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co‐Condensation of Wnt Signalodroplets M Philippi, CP Richter, M Kappen, I Watrinet, Y Miao, M Runge, L Jorde, ... Small 18 (50), 2203723, 2022 | 2 | 2022 |
TGF-β modulates cell fate in human ES cell-derived foregut endoderm by inhibiting multiple endogenous signaling pathways NS Funa, KH de Lichtenberg, MS Hansen, J van Cuyl Kuylenstierna, ... bioRxiv, 2021 | 1 | 2021 |
Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development A Samocha, HM Doh, V Sitarama, QH Nguyen, O Gbenedio, JD Rudolf, ... bioRxiv, 2020 | 1 | 2020 |