Minireview: Addressing the retro-Michael instability of maleimide bioconjugates PA Szijj, C Bahou, V Chudasama Drug Discovery Today: Technologies 30, 27-34, 2018 | 113 | 2018 |
Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones C Bahou, DA Richards, A Maruani, EA Love, F Javaid, S Caddick, ... Organic & Biomolecular Chemistry 16 (8), 1359-1366, 2018 | 80 | 2018 |
A Plug-and-Play Approach for the De Novo Generation of Dually Functionalized Bispecifics A Maruani, PA Szijj, C Bahou, JCF Nogueira, S Caddick, JR Baker, ... Bioconjugate Chemistry 31 (3), 520-529, 2020 | 44 | 2020 |
Disulfide modified IgG1: an investigation of biophysical profile and clinically relevant Fc interactions C Bahou, EA Love, S Leonard, RJ Spears, A Maruani, K Armour, ... Bioconjugate Chemistry 30 (4), 1048-1054, 2019 | 38 | 2019 |
Photoimmunotherapy using cationic and anionic photosensitizer-antibody conjugates against HIV Env-expressing cells M Sadraeian, C Bahou, EF da Cruz, LMR Janini, R Sobhie Diaz, ... International Journal of Molecular Sciences 21 (23), 9151, 2020 | 22 | 2020 |
One-pot thiol–amine bioconjugation to maleimides: simultaneous stabilisation and dual functionalisation A Wall, AG Wills, N Forte, C Bahou, L Bonin, K Nicholls, MT Ma, ... Chemical Science 11 (42), 11455-11460, 2020 | 21 | 2020 |
Leucine-rich alpha-2-glycoprotein 1 (LRG1) as a novel ADC target F Javaid, C Pilotti, C Camilli, D Kallenberg, C Bahou, J Blackburn, ... RSC chemical biology 2 (4), 1206-1220, 2021 | 20 | 2021 |
A Plug-and-Play Platform for the Formation of Trifunctional Cysteine Bioconjugates that also Offers Control over Thiol Cleavability C Bahou, PA Szijj, RJ Spears, A Wall, F Javaid, A Sattikar, EA Love, ... Bioconjugate Chemistry 32 (4), 672-679, 2021 | 16 | 2021 |
Use of pyridazinediones as extracellular cleavable Linkers through Reversible Cysteine Conjugation C Bahou, RJ Spears, AE Aliev, A Maruani, M Fernandez, F Javaid, ... Chemical Communications 55 (98), 14829-14832, 2019 | 15 | 2019 |
Photoinduced photosensitizer–antibody conjugates kill HIV env-expressing cells, also inactivating HIV M Sadraeian, EF da Cruz, RW Boyle, C Bahou, V Chudasama, ... ACS omega 6 (25), 16524-16534, 2021 | 13 | 2021 |
The use of bromopyridazinedione derivatives in chemical biology C Bahou, V Chudasama Organic & Biomolecular Chemistry 20 (30), 5879-5890, 2022 | 11 | 2022 |
Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer PA Szijj, MA Gray, MK Ribi, C Bahou, JCF Nogueira, CR Bertozzi, ... Nature Chemistry 15 (11), 1636-1647, 2023 | 6 | 2023 |
A novel thiol-labile cysteine protecting group for peptide synthesis based on a pyridazinedione (PD) scaffold RJ Spears, C McMahon, M Shamsabadi, C Bahou, IA Thanasi, ... Chemical Communications 58 (5), 645-648, 2022 | 5 | 2022 |
Love EA Leonard S. Spears RJ Maruani A. Armour K. Baker JR Chudasama V C Bahou Bioconjugate Chem 30, 1048-1054, 2019 | 5 | 2019 |
Correction: Use of pyridazinediones as extracellular cleavable linkers through reversible cysteine conjugation C Bahou, RJ Spears, AE Aliev, A Maruani, M Fernandez, F Javaid, ... Chemical Communications 58 (91), 12740-12740, 2022 | 1 | 2022 |
Hydrogel Cross-Linking via Thiol-Reactive Pyridazinediones C Bahou, RJ Spears, AM Ramírez Rosales, LNC Rochet, LJ Barber, ... Biomacromolecules 24 (11), 4646-4652, 2023 | | 2023 |
Use of pyridazinediones for tuneable and reversible covalent cysteine modification applied to peptides, proteins and hydrogels LNC Rochet, C Bahou, JP Wojciechowski, I Koutsopetras, P Britton, ... Chemical Science 14 (47), 13743-13754, 2023 | | 2023 |
Development and Appraisal of the Pyridazinedione Scaffold to Form Next-Generation Bioconjugates C Bahou UCL (University College London), 2020 | | 2020 |