Distinct factors control histone variant H3. 3 localization at specific genomic regions AD Goldberg, LA Banaszynski, KM Noh, PW Lewis, SJ Elsaesser, ... Cell 140 (5), 678-691, 2010 | 1387 | 2010 |
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases D Hockemeyer, F Soldner, C Beard, Q Gao, M Mitalipova, RC DeKelver, ... Nature biotechnology 27 (9), 851-857, 2009 | 1299 | 2009 |
Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial PB Gilbert, DC Montefiori, AB McDermott, Y Fong, D Benkeser, W Deng, ... Science 375 (6576), 43-50, 2022 | 943 | 2022 |
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology SJ Orlando, Y Santiago, RC DeKelver, Y Freyvert, EA Boydston, ... Nucleic acids research 38 (15), e152-e152, 2010 | 266 | 2010 |
The SND proteins constitute an alternative targeting route to the endoplasmic reticulum N Aviram, T Ast, EA Costa, EC Arakel, SG Chuartzman, CH Jan, ... Nature 540 (7631), 134-138, 2016 | 221 | 2016 |
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins MJ Shurtleff, DN Itzhak, JA Hussmann, NT Schirle Oakdale, EA Costa, ... Elife 7, e37018, 2018 | 195 | 2018 |
Defining the physiological role of SRP in protein-targeting efficiency and specificity EA Costa, K Subramanian, J Nunnari, JS Weissman Science 359 (6376), 689-692, 2018 | 185 | 2018 |
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients LE Miller-Vedam, B Bräuning, KD Popova, NT Schirle Oakdale, JL Bonnar, ... elife 9, e62611, 2020 | 74 | 2020 |
Surrogate genetics and metabolic profiling for characterization of human disease alleles JA Mayfield, MW Davies, D Dimster-Denk, N Pleskac, S McCarthy, ... Genetics 190 (4), 1309-1323, 2012 | 53 | 2012 |
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility CR Harding, SM Sidik, B Petrova, NF Gnädig, J Okombo, AL Herneisen, ... Nature Communications 11 (1), 4813, 2020 | 47 | 2020 |
A PEROXO-Tag enables rapid isolation of peroxisomes from human cells GJ Ray, EA Boydston, E Shortt, GA Wyant, S Lourido, WW Chen, ... Iscience 23 (5), 2020 | 27 | 2020 |
Peroxisome function relies on organelle-associated mRNA translation N Dahan, YS Bykov, EA Boydston, A Fadel, Z Gazi, H Hochberg-Laufer, ... Science advances 8 (2), eabk2141, 2022 | 24 | 2022 |
Functional profiling of the Toxoplasma genome during acute mouse infection CJ Giuliano, KJ Wei, FM Harling, BS Waldman, MA Farringer, ... bioRxiv, 2023 | 8 | 2023 |
CRISPR-mediated transcriptional repression in Toxoplasma gondii BM Markus, EA Boydston, S Lourido Msphere 6 (5), 10.1128/msphere. 00474-21, 2021 | 7 | 2021 |
A PEROXO-tag enables rapid isolation of peroxisomes from human cells. iScience 23 GJ Ray, EA Boydston, E Shortt, GA Wyant, S Lourido, WW Chen, ... | 6 | 2020 |
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility. Nat Commun 11: 4813 CR Harding, SM Sidik, B Petrova, NF Gnädig, J Okombo, AL Herneisen, ... | 5 | 2020 |
Functional profiling of theToxoplasmagenome during acute mouse infection CJ Giuliano, KJ Wei, FM Harling, BS Waldman, MA Farringer, ... | 1 | 2023 |
Global analysis of cotranslational protein targeting using proximity-specific ribosome profiling EAB Costa UCSF, 2018 | | 2018 |
Proximity-specific ribosome profiling reveals efficient co-translational ER targeting in the absence of SRP. EA Costa, JS Weissman MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
The SND proteins target SRP-independent substrates to the endoplasmic reticulum. N Aviram, T Ast, S Hassdenteufel, EA Costa, EC Arakel, S Schorr, ... Amer Soc Cell Biology, 2015 | | 2015 |