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Gianluca Nucci
Gianluca Nucci
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Year
Model‐based drug development: a rational approach to efficiently accelerate drug development
PA Milligan, MJ Brown, B Marchant, SW Martin, PH Van Der Graaf, ...
Clinical Pharmacology & Therapeutics 93 (6), 502-514, 2013
2492013
Models of subcutaneous insulin kinetics. A critical review
G Nucci, C Cobelli
Computer methods and programs in biomedicine 62 (3), 249-257, 2000
2352000
The subcutaneous route to insulin dependent diabetes therapy
R Bellazzi, G Nucci, C Cobelli
IEEE Engineering in Medicine and Biology Magazine 20 (1), 54-64, 2001
2152001
A telemedicine support for diabetes management: the T-IDDM project
R Bellazzi, C Larizza, S Montani, A Riva, M Stefanelli, G d'Annunzio, ...
Computer methods and programs in biomedicine 69 (2), 147-161, 2002
1882002
Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals
M Pendergrass, A Bertoldo, R Bonadonna, G Nucci, L Mandarino, ...
American Journal of Physiology-Endocrinology and Metabolism 292 (1), E92-E100, 2007
1342007
Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects
Z Miao, G Nucci, N Amin, R Sharma, V Mascitti, M Tugnait, AD Vaz, ...
Drug Metabolism and Disposition 41 (2), 445-456, 2013
1242013
Design, methods, and evaluation directions of a multi-access service for the management of diabetes mellitus patients
R Bellazzi, M Arcelloni, G Bensa, H Blankenfeld, E Brugués, E Carson, ...
Diabetes technology & therapeutics 5 (4), 621-629, 2003
1012003
Innovative randomized phase I study and dosing regimen selection to accelerate and inform pivotal COVID‐19 trial of nirmatrelvir
RSP Singh, SS Toussi, F Hackman, PL Chan, R Rao, R Allen, L Van Eyck, ...
Clinical Pharmacology & Therapeutics 112 (1), 101-111, 2022
962022
The orexin antagonist SB-649868 promotes and maintains sleep in men with primary insomnia
P Bettica, L Squassante, S Zamuner, G Nucci, H Danker-Hopfe, E Ratti
Sleep 35 (8), 1097-1104, 2012
962012
Modeling airflow-related shear stress during heterogeneous constriction and mechanical ventilation
G Nucci, B Suki, K Lutchen
Journal of Applied Physiology 95 (1), 348-356, 2003
892003
Dose‐ranging efficacy and safety study of ertugliflozin, a sodium‐glucose co‐transporter 2 inhibitor, in patients with type 2 diabetes on a background of metformin
NB Amin, X Wang, SM Jain, DS Lee, G Nucci, JM Rusnak
Diabetes, Obesity and Metabolism 17 (6), 591-598, 2015
782015
Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist
P Bettica, G Nucci, C Pyke, L Squassante, S Zamuner, E Ratti, R Gomeni, ...
Journal of Psychopharmacology 26 (8), 1058-1070, 2012
742012
Blood pressure‐lowering effect of the sodium glucose co‐transporter‐2 inhibitor ertugliflozin, assessed via ambulatory blood pressure monitoring in patients with type 2 …
NB Amin, X Wang, JR Mitchell, DS Lee, G Nucci, JM Rusnak
Diabetes, Obesity and Metabolism 17 (8), 805-808, 2015
722015
Multiple dose pharmacokinetics of paroxetine in children and adolescents with major depressive disorder or obsessive–compulsive disorder
RL Findling, G Nucci, AA Piergies, R Gomeni, EI Bartolic, R Fong, ...
Neuropsychopharmacology 31 (6), 1274-1285, 2006
622006
Characterization of a 7% carbon dioxide (CO2) inhalation paradigm to evoke anxiety symptoms in healthy subjects
SZ Poma, S Milleri, L Squassante, G Nucci, M Bani, GI Perini, ...
Journal of Psychopharmacology 19 (5), 494-503, 2005
592005
On-line monitoring of lung mechanics during spontaneous breathing: a physiological study
S Khirani, G Polese, A Aliverti, L Appendini, G Nucci, A Pedotti, ...
Respiratory medicine 104 (3), 463-471, 2010
492010
Overview of the clinical pharmacology of ertugliflozin, a novel sodium-glucose cotransporter 2 (SGLT2) inhibitor
DJ Fediuk, G Nucci, VK Dawra, DL Cutler, NB Amin, SG Terra, RA Boyd, ...
Clinical Pharmacokinetics 59, 949-965, 2020
412020
Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients
AM Catafau, MM Penengo, G Nucci, S Bullich, I Corripio, E Parellada, ...
Journal of Psychopharmacology 22 (8), 882-894, 2008
382008
Within-subject comparison of striatal D2 receptor occupancy measurements using [123I] IBZM SPECT and [11C] Raclopride PET
AM Catafau, M Suarez, S Bullich, J Llop, G Nucci, RN Gunn, C Brittain, ...
Neuroimage 46 (2), 447-458, 2009
372009
A morphometric model of lung mechanics for time-domain analysis of alveolar pressures during mechanical ventilation
G Nucci, S Tessarin, C Cobelli
Annals of Biomedical Engineering 30, 537-545, 2002
372002
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