Model‐based drug development: a rational approach to efficiently accelerate drug development PA Milligan, MJ Brown, B Marchant, SW Martin, PH Van Der Graaf, ... Clinical Pharmacology & Therapeutics 93 (6), 502-514, 2013 | 249 | 2013 |
Models of subcutaneous insulin kinetics. A critical review G Nucci, C Cobelli Computer methods and programs in biomedicine 62 (3), 249-257, 2000 | 235 | 2000 |
The subcutaneous route to insulin dependent diabetes therapy R Bellazzi, G Nucci, C Cobelli IEEE Engineering in Medicine and Biology Magazine 20 (1), 54-64, 2001 | 215 | 2001 |
A telemedicine support for diabetes management: the T-IDDM project R Bellazzi, C Larizza, S Montani, A Riva, M Stefanelli, G d'Annunzio, ... Computer methods and programs in biomedicine 69 (2), 147-161, 2002 | 188 | 2002 |
Muscle glucose transport and phosphorylation in type 2 diabetic, obese nondiabetic, and genetically predisposed individuals M Pendergrass, A Bertoldo, R Bonadonna, G Nucci, L Mandarino, ... American Journal of Physiology-Endocrinology and Metabolism 292 (1), E92-E100, 2007 | 134 | 2007 |
Pharmacokinetics, metabolism, and excretion of the antidiabetic agent ertugliflozin (PF-04971729) in healthy male subjects Z Miao, G Nucci, N Amin, R Sharma, V Mascitti, M Tugnait, AD Vaz, ... Drug Metabolism and Disposition 41 (2), 445-456, 2013 | 124 | 2013 |
Design, methods, and evaluation directions of a multi-access service for the management of diabetes mellitus patients R Bellazzi, M Arcelloni, G Bensa, H Blankenfeld, E Brugués, E Carson, ... Diabetes technology & therapeutics 5 (4), 621-629, 2003 | 101 | 2003 |
Innovative randomized phase I study and dosing regimen selection to accelerate and inform pivotal COVID‐19 trial of nirmatrelvir RSP Singh, SS Toussi, F Hackman, PL Chan, R Rao, R Allen, L Van Eyck, ... Clinical Pharmacology & Therapeutics 112 (1), 101-111, 2022 | 96 | 2022 |
The orexin antagonist SB-649868 promotes and maintains sleep in men with primary insomnia P Bettica, L Squassante, S Zamuner, G Nucci, H Danker-Hopfe, E Ratti Sleep 35 (8), 1097-1104, 2012 | 96 | 2012 |
Modeling airflow-related shear stress during heterogeneous constriction and mechanical ventilation G Nucci, B Suki, K Lutchen Journal of Applied Physiology 95 (1), 348-356, 2003 | 89 | 2003 |
Dose‐ranging efficacy and safety study of ertugliflozin, a sodium‐glucose co‐transporter 2 inhibitor, in patients with type 2 diabetes on a background of metformin NB Amin, X Wang, SM Jain, DS Lee, G Nucci, JM Rusnak Diabetes, Obesity and Metabolism 17 (6), 591-598, 2015 | 78 | 2015 |
Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist P Bettica, G Nucci, C Pyke, L Squassante, S Zamuner, E Ratti, R Gomeni, ... Journal of Psychopharmacology 26 (8), 1058-1070, 2012 | 74 | 2012 |
Blood pressure‐lowering effect of the sodium glucose co‐transporter‐2 inhibitor ertugliflozin, assessed via ambulatory blood pressure monitoring in patients with type 2 … NB Amin, X Wang, JR Mitchell, DS Lee, G Nucci, JM Rusnak Diabetes, Obesity and Metabolism 17 (8), 805-808, 2015 | 72 | 2015 |
Multiple dose pharmacokinetics of paroxetine in children and adolescents with major depressive disorder or obsessive–compulsive disorder RL Findling, G Nucci, AA Piergies, R Gomeni, EI Bartolic, R Fong, ... Neuropsychopharmacology 31 (6), 1274-1285, 2006 | 62 | 2006 |
Characterization of a 7% carbon dioxide (CO2) inhalation paradigm to evoke anxiety symptoms in healthy subjects SZ Poma, S Milleri, L Squassante, G Nucci, M Bani, GI Perini, ... Journal of Psychopharmacology 19 (5), 494-503, 2005 | 59 | 2005 |
On-line monitoring of lung mechanics during spontaneous breathing: a physiological study S Khirani, G Polese, A Aliverti, L Appendini, G Nucci, A Pedotti, ... Respiratory medicine 104 (3), 463-471, 2010 | 49 | 2010 |
Overview of the clinical pharmacology of ertugliflozin, a novel sodium-glucose cotransporter 2 (SGLT2) inhibitor DJ Fediuk, G Nucci, VK Dawra, DL Cutler, NB Amin, SG Terra, RA Boyd, ... Clinical Pharmacokinetics 59, 949-965, 2020 | 41 | 2020 |
Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients AM Catafau, MM Penengo, G Nucci, S Bullich, I Corripio, E Parellada, ... Journal of Psychopharmacology 22 (8), 882-894, 2008 | 38 | 2008 |
Within-subject comparison of striatal D2 receptor occupancy measurements using [123I] IBZM SPECT and [11C] Raclopride PET AM Catafau, M Suarez, S Bullich, J Llop, G Nucci, RN Gunn, C Brittain, ... Neuroimage 46 (2), 447-458, 2009 | 37 | 2009 |
A morphometric model of lung mechanics for time-domain analysis of alveolar pressures during mechanical ventilation G Nucci, S Tessarin, C Cobelli Annals of Biomedical Engineering 30, 537-545, 2002 | 37 | 2002 |