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Yixiang Xu
Yixiang Xu
Bristol Myers Squib
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Year
LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration
M Deng, X Gui, J Kim, L Xie, W Chen, Z Li, L He, Y Chen, H Chen, W Luo, ...
Nature 562 (7728), 605-609, 2018
2052018
Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression
Y Xu, L Qin, T Sun, H Wu, T He, Z Yang, Q Mo, L Liao, J Xu
Oncogene, 1157-1166, 2017
1642017
Breast tumor cell-specific knockout of Twist1 inhibits cancer cell plasticity, dissemination, and lung metastasis in mice
Y Xu, DK Lee, Z Feng, Y Xu, W Bu, Y Li, L Liao, J Xu
Proceedings of the National Academy of Sciences 114 (43), 11494-11499, 2017
1092017
NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
L Qin, YL Wu, MJ Toneff, D Li, L Liao, X Gao, FT Bane, JCY Tien, Y Xu, ...
Cancer research 74 (13), 3477-3488, 2014
672014
Disrupting LILRB4/APOE interaction by an efficacious humanized antibody reverses T-cell suppression and blocks AML development
X Gui, M Deng, H Song, Y Chen, J Xie, Z Li, L He, F Huang, Y Xu, ...
Cancer immunology research 7 (8), 1244-1257, 2019
622019
Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness
Y Xu, Q Chen, W Li, X Su, T Chen, Y Liu, Y Zhao, C Yu
Oncogene 29 (23), 3386-3397, 2010
602010
Nuclear receptor NR4A1 is a tumor suppressor down-regulated in triple-negative breast cancer
JX Hongmei Wu, Jiong Bi, Yan Peng2, Lei Huo3, Xiaobin Yu, Zhihui Yang ...
Oncotarget, 2017
482017
SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer
JJ Xu Y, Hu B, Qin L, Zhao L, Wang Q, Wang Q, Xu Y
Int J Biol Sci., 2014
472014
The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer
JCY Tien, Z Liu, L Liao, F Wang, Y Xu, YL Wu, N Zhou, M Ittmann, J Xu
Cancer research 73 (13), 3997-4008, 2013
462013
Inducible knockout of Twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting Twist1 as a preferential cancer target.
XJ Xu Y, Xu Y, Liao L, Zhou N, Theissen SM, Liao XH, Nguyen H, Ludwig T, Qin ...
Am J Pathol., 2013
432013
Tamoxifen inhibits ER-negative breast cancer cell invasion and metastasis by accelerating Twist1 degradation
G Ma, J He, Y Yu, Y Xu, X Yu, J Martinez, DM Lonard, J Xu
International journal of biological sciences 11 (5), 618, 2015
412015
NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1α-and AP-1-mediated VEGFa transcription
L Qin, Y Xu, Y Xu, G Ma, L Liao, Y Wu, Y Li, X Wang, X Wang, J Jiang, ...
Oncotarget 6 (27), 23890, 2015
382015
Steroid receptor coactivator 3 is required for clearing bacteria and repressing inflammatory response in Escherichia coli-induced septic peritonitis
Q Chen, T Chen, Y Xu, J Zhu, Y Jiang, Y Zhao, J Xu, C Yu
The Journal of Immunology 185 (9), 5444-5452, 2010
332010
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis
G Wu, Y Xu, RD Schultz, H Chen, J Xie, M Deng, X Liu, X Gui, S John, ...
Nature cancer 2 (11), 1170-1184, 2021
292021
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism.
YC Chen T, Chen Q, Xu Y, Zhou Q, Zhu J, Zhang H, Wu Q, Xu J
J Hepatol. 56 (1), 210-217, 2012
262012
The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland
L Qin, Y Xu, X Yu, MJ Toneff, D Li, L Liao, JD Martinez, Y Li, J Xu
Oncotarget 8 (49), 84761, 2017
202017
T-cell receptor mimic (TCRm) antibody therapeutics against intracellular proteins
Y Xu, GT Salazar, N Zhang, Z An
Antibody therapeutics 2 (1), 22-32, 2019
142019
Establishment of a cell-based assay for examining the expression of tumor necrosis factor alpha (TNF-α) gene
Q Chen, Y Zhao, Z Cheng, Y Xu, C Yu
Applied microbiology and biotechnology 80, 357-363, 2008
92008
Common genomic aberrations in mouse and human breast cancers with concurrent P53 deficiency and activated PTEN-PI3K-AKT pathway
JD Martinez, Q Mo, Y Xu, L Qin, Y Li, J Xu
International journal of biological sciences 18 (1), 229, 2022
32022
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
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