LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration M Deng, X Gui, J Kim, L Xie, W Chen, Z Li, L He, Y Chen, H Chen, W Luo, ... Nature 562 (7728), 605-609, 2018 | 205 | 2018 |
Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression Y Xu, L Qin, T Sun, H Wu, T He, Z Yang, Q Mo, L Liao, J Xu Oncogene, 1157-1166, 2017 | 164 | 2017 |
Breast tumor cell-specific knockout of Twist1 inhibits cancer cell plasticity, dissemination, and lung metastasis in mice Y Xu, DK Lee, Z Feng, Y Xu, W Bu, Y Li, L Liao, J Xu Proceedings of the National Academy of Sciences 114 (43), 11494-11499, 2017 | 109 | 2017 |
NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis L Qin, YL Wu, MJ Toneff, D Li, L Liao, X Gao, FT Bane, JCY Tien, Y Xu, ... Cancer research 74 (13), 3477-3488, 2014 | 67 | 2014 |
Disrupting LILRB4/APOE interaction by an efficacious humanized antibody reverses T-cell suppression and blocks AML development X Gui, M Deng, H Song, Y Chen, J Xie, Z Li, L He, F Huang, Y Xu, ... Cancer immunology research 7 (8), 1244-1257, 2019 | 62 | 2019 |
Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness Y Xu, Q Chen, W Li, X Su, T Chen, Y Liu, Y Zhao, C Yu Oncogene 29 (23), 3386-3397, 2010 | 60 | 2010 |
Nuclear receptor NR4A1 is a tumor suppressor down-regulated in triple-negative breast cancer JX Hongmei Wu, Jiong Bi, Yan Peng2, Lei Huo3, Xiaobin Yu, Zhihui Yang ... Oncotarget, 2017 | 48 | 2017 |
SRC-1 and Twist1 expression positively correlates with a poor prognosis in human breast cancer JJ Xu Y, Hu B, Qin L, Zhao L, Wang Q, Wang Q, Xu Y Int J Biol Sci., 2014 | 47 | 2014 |
The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer JCY Tien, Z Liu, L Liao, F Wang, Y Xu, YL Wu, N Zhou, M Ittmann, J Xu Cancer research 73 (13), 3997-4008, 2013 | 46 | 2013 |
Inducible knockout of Twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting Twist1 as a preferential cancer target. XJ Xu Y, Xu Y, Liao L, Zhou N, Theissen SM, Liao XH, Nguyen H, Ludwig T, Qin ... Am J Pathol., 2013 | 43 | 2013 |
Tamoxifen inhibits ER-negative breast cancer cell invasion and metastasis by accelerating Twist1 degradation G Ma, J He, Y Yu, Y Xu, X Yu, J Martinez, DM Lonard, J Xu International journal of biological sciences 11 (5), 618, 2015 | 41 | 2015 |
NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1α-and AP-1-mediated VEGFa transcription L Qin, Y Xu, Y Xu, G Ma, L Liao, Y Wu, Y Li, X Wang, X Wang, J Jiang, ... Oncotarget 6 (27), 23890, 2015 | 38 | 2015 |
Steroid receptor coactivator 3 is required for clearing bacteria and repressing inflammatory response in Escherichia coli-induced septic peritonitis Q Chen, T Chen, Y Xu, J Zhu, Y Jiang, Y Zhao, J Xu, C Yu The Journal of Immunology 185 (9), 5444-5452, 2010 | 33 | 2010 |
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis G Wu, Y Xu, RD Schultz, H Chen, J Xie, M Deng, X Liu, X Gui, S John, ... Nature cancer 2 (11), 1170-1184, 2021 | 29 | 2021 |
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism. YC Chen T, Chen Q, Xu Y, Zhou Q, Zhu J, Zhang H, Wu Q, Xu J J Hepatol. 56 (1), 210-217, 2012 | 26 | 2012 |
The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland L Qin, Y Xu, X Yu, MJ Toneff, D Li, L Liao, JD Martinez, Y Li, J Xu Oncotarget 8 (49), 84761, 2017 | 20 | 2017 |
T-cell receptor mimic (TCRm) antibody therapeutics against intracellular proteins Y Xu, GT Salazar, N Zhang, Z An Antibody therapeutics 2 (1), 22-32, 2019 | 14 | 2019 |
Establishment of a cell-based assay for examining the expression of tumor necrosis factor alpha (TNF-α) gene Q Chen, Y Zhao, Z Cheng, Y Xu, C Yu Applied microbiology and biotechnology 80, 357-363, 2008 | 9 | 2008 |
Common genomic aberrations in mouse and human breast cancers with concurrent P53 deficiency and activated PTEN-PI3K-AKT pathway JD Martinez, Q Mo, Y Xu, L Qin, Y Li, J Xu International journal of biological sciences 18 (1), 229, 2022 | 3 | 2022 |
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy | | |