| Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ... Nature communications 13 (1), 3788, 2022 | 70 | 2022 |
| Computational methods for characterizing and learning from heterogeneous cell signaling data PC Kinnunen, KE Luker, GD Luker, JJ Linderman Current opinion in systems biology 26, 98-108, 2021 | 7 | 2021 |
| Pre-existing cell states control heterogeneity of both EGFR and CXCR4 signaling PC Spinosa, PC Kinnunen, BA Humphries, GD Luker, KE Luker, ... Cellular and Molecular Bioengineering 14, 49-64, 2021 | 7 | 2021 |
| Computational modeling implicates protein scaffolding in p38 regulation of Akt PC Kinnunen, GD Luker, KE Luker, JJ Linderman Journal of theoretical biology 555, 111294, 2022 | 3 | 2022 |
| Oscillatory ERK Signaling and Morphology Determine Heterogeneity of Breast Cancer Cell Chemotaxis via MEK-ERK and p38-MAPK Signaling Pathways KKY Ho, S Srivastava, PC Kinnunen, K Garikipati, GD Luker, KE Luker Bioengineering 10 (2), 269, 2023 | 2 | 2023 |
| Machine learning-assisted imaging analysis of a human epiblast model AM Resto Irizarry, SN Esfahani, Y Zheng, RZ Yan, P Kinnunen, J Fu Integrative Biology 13 (9), 221-229, 2021 | 2 | 2021 |
| DNA Origami and Rheology P Kinnunen The Ohio State University, 2016 | 2 | 2016 |
| Partial differential equation-based inference of migration and proliferation mechanisms in cancer cell populations PC Kinnunen, S Srivastava, Z Wang, KKY Ho, BA Humphries, S Chen, ... arXiv preprint arXiv:2302.09445, 2023 | 1 | 2023 |
| Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling J Fontana, D Sparkman-Yager, I Faulkner, R Cardiff, C Kiattisewee, ... bioRxiv, 2023.11. 17.567465, 2023 | 1 | 2023 |
| Characterizing heterogeneous single-cell dose responses computationally and experimentally using threshold inhibition surfaces and dose-titration assays PC Kinnunen, BA Humphries, GD Luker, KE Luker, JJ Linderman npj Systems Biology and Applications 10 (1), 42, 2024 | | 2024 |
| Integrating Inverse Reinforcement Learning into Data-Driven Mechanistic Computational Models: A Novel Paradigm to Decode Cancer Cell Heterogeneity P Kinnunen, KKY Ho, S Srivastava, C Huang, W Shen, K Garikipati, ... Frontiers in Systems Biology 4, 1333760, 2024 | | 2024 |
Jennifer LindermanProfessor of Chemical Engineering, University of MichiganVerified email at umich.edu
