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MARIANA G. FRONZA
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Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice
AM Casaril, M Domingues, M Fronza, B Vieira, K Begnini, EJ Lenardão, ...
Journal of Psychopharmacology 31 (9), 1263-1273, 2017
642017
Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test
LMP Brod, MG Fronza, JP Vargas, DS Luedtke, C Luchese, EA Wilhelm, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 201-207, 2016
502016
Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities
SF Fonseca, NB Padilha, S Thurow, JA Roehrs, L Savegnago, ...
Ultrasonics Sonochemistry 39, 827-836, 2017
472017
α-(phenylselanyl) acetophenone mitigates reserpine-induced pain–depression dyad: Behavioral, biochemical and molecular docking evidences
FSS Sousa, PT Birmann, R Baldinotti, MG Fronza, R Balaguez, D Alves, ...
Brain Research Bulletin 142, 129-137, 2018
372018
Lipopolysaccharide-induced depressive-like, anxiogenic-like and hyperalgesic behavior is attenuated by acute administration of α-(phenylselanyl) acetophenone in mice
FSS Sousa, PT Birmann, SR Bampi, MG Fronza, R Balaguez, D Alves, ...
Neuropharmacology 146, 128-137, 2019
332019
Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer’s disease
MG Fronza, R Baldinotti, MC Martins, B Goldani, BT Dalberto, FS Kremer, ...
Scientific Reports 9 (1), 7276, 2019
322019
Phenylselanyl-1 H-1, 2, 3-triazole-4-carbonitriles: Synthesis, antioxidant properties and use as precursors to highly functionalized tetrazoles
L Savegnago, M do Sacramento, LMP Brod, MG Fronza, N Seus, ...
RSC advances 6 (10), 8021-8031, 2016
322016
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and …
MG Fronza, R Baldinotti, J Fetter, SG Rosa, M Sacramento, CW Nogueira, ...
Brain, behavior, and immunity 99, 177-191, 2022
212022
The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice
SR Bampi, AM Casaril, MG Fronza, M Domingues, B Vieira, KR Begnini, ...
Brain research bulletin 161, 158-165, 2020
212020
Effect of QTC-4-MeOBnE treatment on memory, neurodegeneration, and neurogenesis in a streptozotocin-induced mouse model of Alzheimer’s disease
MG Fronza, R Baldinotti, M Sacramento, J Gutierres, FB Carvalho, ...
ACS chemical neuroscience 12 (1), 109-122, 2020
192020
Apoptosis induction by 7-chloroquinoline-1, 2, 3-triazoyl carboxamides in triple negative breast cancer cells
KR Begnini, WR Duarte, LP da Silva, JH Buss, BS Goldani, M Fronza, ...
Biomedicine & Pharmacotherapy 91, 510-516, 2017
172017
Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice
LM Pinto Brod, MG Fronza, JP Vargas, DS Lüdtke, CA Brüning, ...
Psychopharmacology 234, 717-725, 2017
172017
7-Chloroquinoline-1, 2, 3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells
MS Sonego, NV Segatto, L Dame, M Fronza, CB Gomes, TL Oliveira, ...
Investigational New Drugs 38, 1020-1030, 2020
152020
Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na+/K+-ATPase in an …
MP Pinz, AG Vogt, K da Costa Rodrigues, AS Dos Reis, LFB Duarte, ...
Metabolic Brain Disease 36, 871-888, 2021
132021
QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity, and apoptosis
MG Fronza, R Baldinotti, J Fetter, M Sacramento, FSS Sousa, FK Seixas, ...
ACS Chemical Neuroscience 11 (9), 1259-1269, 2020
132020
Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system
VC Bortolotto, SM Araujo, FC Pinheiro, MR Poetini, LB Meichtry, ...
Journal of Psychiatric Research 144, 225-233, 2021
122021
Synthesis, photophysics and biomolecule interactive studies of new hybrid benzo-2, 1, 3-thiadiazoles
JSS Neto, R Krüger, RA Balaguez, MG Fronza, TV Acunha, RS Oliboni, ...
New Journal of Chemistry 44 (7), 2768-2780, 2020
122020
Synthesis, Molecular Docking, and Preliminary Evaluation of 2‐(1, 2, 3‐Triazoyl) benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease
GP Costa, RSM Baldinotti, MG Fronza, JER Nascimento, ÍFC Dias, ...
ChemMedChem 15 (7), 610-622, 2020
112020
Alkynylselenium-functionalized benzothiadiazoles: Synthesis, photophysics, electrochemistry, and biomolecular interaction studies
CH Silveira, MG Fronza, RA Balaguez, AME Larroza, L Savegnago, ...
Dyes and Pigments 185, 108910, 2021
92021
Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice
MG Fronza, LMP Brod, AM Casaril, M Sacramento, D Alves, L Savegnago
Plos one 12 (11), e0187445, 2017
92017
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