Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice AM Casaril, M Domingues, M Fronza, B Vieira, K Begnini, EJ Lenardão, ... Journal of Psychopharmacology 31 (9), 1263-1273, 2017 | 64 | 2017 |
Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test LMP Brod, MG Fronza, JP Vargas, DS Luedtke, C Luchese, EA Wilhelm, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 201-207, 2016 | 50 | 2016 |
Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities SF Fonseca, NB Padilha, S Thurow, JA Roehrs, L Savegnago, ... Ultrasonics Sonochemistry 39, 827-836, 2017 | 47 | 2017 |
α-(phenylselanyl) acetophenone mitigates reserpine-induced pain–depression dyad: Behavioral, biochemical and molecular docking evidences FSS Sousa, PT Birmann, R Baldinotti, MG Fronza, R Balaguez, D Alves, ... Brain Research Bulletin 142, 129-137, 2018 | 37 | 2018 |
Lipopolysaccharide-induced depressive-like, anxiogenic-like and hyperalgesic behavior is attenuated by acute administration of α-(phenylselanyl) acetophenone in mice FSS Sousa, PT Birmann, SR Bampi, MG Fronza, R Balaguez, D Alves, ... Neuropharmacology 146, 128-137, 2019 | 33 | 2019 |
Rational design, cognition and neuropathology evaluation of QTC-4-MeOBnE in a streptozotocin-induced mouse model of sporadic Alzheimer’s disease MG Fronza, R Baldinotti, MC Martins, B Goldani, BT Dalberto, FS Kremer, ... Scientific Reports 9 (1), 7276, 2019 | 32 | 2019 |
Phenylselanyl-1 H-1, 2, 3-triazole-4-carbonitriles: Synthesis, antioxidant properties and use as precursors to highly functionalized tetrazoles L Savegnago, M do Sacramento, LMP Brod, MG Fronza, N Seus, ... RSC advances 6 (10), 8021-8031, 2016 | 32 | 2016 |
Beneficial effects of QTC-4-MeOBnE in an LPS-induced mouse model of depression and cognitive impairments: The role of blood-brain barrier permeability, NF-κB signaling, and … MG Fronza, R Baldinotti, J Fetter, SG Rosa, M Sacramento, CW Nogueira, ... Brain, behavior, and immunity 99, 177-191, 2022 | 21 | 2022 |
The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice SR Bampi, AM Casaril, MG Fronza, M Domingues, B Vieira, KR Begnini, ... Brain research bulletin 161, 158-165, 2020 | 21 | 2020 |
Effect of QTC-4-MeOBnE treatment on memory, neurodegeneration, and neurogenesis in a streptozotocin-induced mouse model of Alzheimer’s disease MG Fronza, R Baldinotti, M Sacramento, J Gutierres, FB Carvalho, ... ACS chemical neuroscience 12 (1), 109-122, 2020 | 19 | 2020 |
Apoptosis induction by 7-chloroquinoline-1, 2, 3-triazoyl carboxamides in triple negative breast cancer cells KR Begnini, WR Duarte, LP da Silva, JH Buss, BS Goldani, M Fronza, ... Biomedicine & Pharmacotherapy 91, 510-516, 2017 | 17 | 2017 |
Modulation of PKA, PKC, CAMKII, ERK 1/2 pathways is involved in the acute antidepressant-like effect of (octylseleno)-xylofuranoside (OSX) in mice LM Pinto Brod, MG Fronza, JP Vargas, DS Lüdtke, CA Brüning, ... Psychopharmacology 234, 717-725, 2017 | 17 | 2017 |
7-Chloroquinoline-1, 2, 3-triazoyl carboxamides induce cell cycle arrest and apoptosis in human bladder carcinoma cells MS Sonego, NV Segatto, L Dame, M Fronza, CB Gomes, TL Oliveira, ... Investigational New Drugs 38, 1020-1030, 2020 | 15 | 2020 |
Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na+/K+-ATPase in an … MP Pinz, AG Vogt, K da Costa Rodrigues, AS Dos Reis, LFB Duarte, ... Metabolic Brain Disease 36, 871-888, 2021 | 13 | 2021 |
QTC-4-MeOBnE rescues scopolamine-induced memory deficits in mice by targeting oxidative stress, neuronal plasticity, and apoptosis MG Fronza, R Baldinotti, J Fetter, M Sacramento, FSS Sousa, FK Seixas, ... ACS Chemical Neuroscience 11 (9), 1259-1269, 2020 | 13 | 2020 |
Chrysin restores memory deficit in hypothyroidism mice: Behavioral, neurochemical and computational approaches involving the neurotrophinergic system VC Bortolotto, SM Araujo, FC Pinheiro, MR Poetini, LB Meichtry, ... Journal of Psychiatric Research 144, 225-233, 2021 | 12 | 2021 |
Synthesis, photophysics and biomolecule interactive studies of new hybrid benzo-2, 1, 3-thiadiazoles JSS Neto, R Krüger, RA Balaguez, MG Fronza, TV Acunha, RS Oliboni, ... New Journal of Chemistry 44 (7), 2768-2780, 2020 | 12 | 2020 |
Synthesis, Molecular Docking, and Preliminary Evaluation of 2‐(1, 2, 3‐Triazoyl) benzaldehydes As Multifunctional Agents for the Treatment of Alzheimer's Disease GP Costa, RSM Baldinotti, MG Fronza, JER Nascimento, ÍFC Dias, ... ChemMedChem 15 (7), 610-622, 2020 | 11 | 2020 |
Alkynylselenium-functionalized benzothiadiazoles: Synthesis, photophysics, electrochemistry, and biomolecular interaction studies CH Silveira, MG Fronza, RA Balaguez, AME Larroza, L Savegnago, ... Dyes and Pigments 185, 108910, 2021 | 9 | 2021 |
Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice MG Fronza, LMP Brod, AM Casaril, M Sacramento, D Alves, L Savegnago Plos one 12 (11), e0187445, 2017 | 9 | 2017 |