| Plasmid-based one-pot saturation mutagenesis EE Wrenbeck, JR Klesmith, JA Stapleton, A Adeniran, KEJ Tyo, ... Nature Methods 13 (11), 928-930, 2016 | 175 | 2016 |
| Single-mutation fitness landscapes for an enzyme on multiple substrates reveal specificity is globally encoded EE Wrenbeck, LR Azouz, TA Whitehead Nature communications 8 (1), 15695, 2017 | 139 | 2017 |
| Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning JR Klesmith, JP Bacik, EE Wrenbeck, R Michalczyk, TA Whitehead Proceedings of the National Academy of Sciences 114 (9), 2265-2270, 2017 | 139 | 2017 |
| Deep sequencing methods for protein engineering and design EE Wrenbeck, MS Faber, TA Whitehead Current opinion in structural biology 45, 36-44, 2017 | 112 | 2017 |
| The interrelationship between promoter strength, gene expression, and growth rate MS Bienick, KW Young, JR Klesmith, EE Detwiler, KJ Tomek, ... PLoS One 9 (10), e109105, 2014 | 88 | 2014 |
| An automated data-driven pipeline for improving heterologous enzyme expression EE Wrenbeck, MA Bedewitz, JR Klesmith, S Noshin, CS Barry, ... ACS synthetic biology 8 (3), 474-481, 2019 | 29 | 2019 |
| Impact of in vivo protein folding probability on local fitness landscapes MS Faber, EE Wrenbeck, LR Azouz, PJ Steiner, TA Whitehead Molecular biology and evolution 36 (12), 2764-2777, 2019 | 22 | 2019 |
| Deep Sequencing Driven Protein Engineering: New Methods and Applications in Studying the Constraints of Functional Enzyme Evolution EE Wrenbeck Michigan State University, 2017 | 1 | 2017 |
| Methods for generating single-or multi-site mutagenesis J Klesmith, J Stapleton, T Whitehead, E Wrenbeck US Patent 11,155,811, 2021 | | 2021 |
| Automating the Engineering of Improved Enzymes for Biomanufacturing E Wrenbeck, M Bedewitz, R Noshin, T Whitehead 2018 AIChE Annual Meeting, 2018 | | 2018 |
| Nicking mutagenesis: User-defined, single-pot comprehensive mutagenesis T Whitehead, E Wrenbeck ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| Nicking Mutagenesis: A Plasmid-Based Single-Pot Saturation Mutagenesis Method EE Wrenbeck, JR Klesmith, JA Stapleton, TA Whitehead PROTEIN SCIENCE 25, 74-74, 2016 | | 2016 |
| Comprehensive evaluation of protein sequence-function landscapes using deep sequencing JR Klesmith, EE Wrenbeck, CA Kowalsky, TA Whitehead PROTEIN SCIENCE 25, 73-73, 2016 | | 2016 |
| Nicking Mutagenesis: comprehensive single-site saturation mutagenesis T Whitehead, E Wrenbeck, J Klesmith, J Stapleton | | 2016 |
| Impact of initial protein stability on local fitness landscapes MS Faber, EE Wrenbeck, LR Azouz, PJ Steiner, TA Whitehead | | |
Justin R. KlesmithZoetis, Kalamazoo, MIVerified email at zoetis.com
