Para-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells X Zhou, J Bouitbir, ME Liechti, S Krähenbühl, RV Mancuso International journal of molecular sciences 21 (8), 2841, 2020 | 18 | 2020 |
Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones X Zhou, J Bouitbir, ME Liechti, S Krähenbühl, RV Mancuso Cells 9 (4), 965, 2020 | 10 | 2020 |
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines NJ Roos, RV Mancuso, GM Sanvee, J Bouitbir, S Krähenbühl Food and Chemical Toxicology 162, 112869, 2022 | 5 | 2022 |
Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition RV Mancuso, K Welzenbach, P Steinberger, S Krähenbühl, ... Biochemical pharmacology 119, 42-55, 2016 | 5 | 2016 |
Anti‐αLβ2 antibodies reveal novel endocytotic cross‐modulatory functionality RV Mancuso, J Casper, AG Schmidt, S Krähenbühl, G Weitz‐Schmidt British Journal of Pharmacology 177 (12), 2696-2711, 2020 | 4 | 2020 |
Small molecule LFA-1 inhibitors W Breitenstein, M Huerzeler, T Kelly, R Mancuso, G Schneider, ... US Patent 10,077,238, 2018 | 3 | 2018 |
A novel multi‐parameter assay to dissect the pharmacological effects of different modes of integrin αLβ2 inhibition in whole blood K Welzenbach, RV Mancuso, S Krähenbühl, G Weitz‐Schmidt British journal of pharmacology 172 (20), 4875-4887, 2015 | 2 | 2015 |
Allosteric targeting resolves limitations of earlier LFA-1 directed modalities RV Mancuso, G Schneider, M Hürzeler, M Gut, J Zurflüh, W Breitenstein, ... Biochemical Pharmacology 211, 115504, 2023 | 1 | 2023 |
Design and Characterization of Mutated Variants of the Oncotoxic Parvoviral Protein NS1 P Hauswirth, P Graber, K Buczak, RV Mancuso, SH Schenk, JPF Nüesch, ... Viruses 15 (1), 209, 2023 | 1 | 2023 |
Mechanisms of hepatocellular toxicity associated with the components of St. John’s Wort extract hypericin and hyperforin in HepG2 and HepaRG cells VF Abegg, MV Panajatovic, RV Mancuso, JA Allard, U Duthaler, ... Toxicology Letters, 2024 | | 2024 |
109 Investigation of complement-related integrin receptors using a screening platform and newly developed tool compounds C Lamers, C Sommer, C Leiggener, S Vogt, L Cuillo, M Tschanz, ... Immunobiology 228 (5), 152560, 2023 | | 2023 |
Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models JS Bolten, RV Mancuso, NJ Roos, A Mayr, RD Puligilla, L Kraus, ... Toxicology and Applied Pharmacology 466, 116493, 2023 | | 2023 |
Establishing a screening platform for the biological evaluation and modulation of complement-related integrin receptors C Pluss, C Lamers, R Mancuso, S Rabbani, D Ricklin MOLECULAR IMMUNOLOGY 141, 173-173, 2022 | | 2022 |
Small molecule lfa-1 inhibitors W Breitenstein, M Huerzeler, T Kelly, R MANCUSO, G Schneider, ... | | 2021 |
Small molecule lfa-1 inhibitors W Breitenstein, M Huerzeler, T Kelly, R Mancuso, G Schneider, ... US Patent App. 16/053,510, 2019 | | 2019 |
Development of a new generation of integrin targeting drugs for the treatment of immune-mediated diseases WS Gabriele, R Mancuso, M Huerzeler, S Kraehenbuehl, G Schneider, ... 日本薬理学会年会要旨集 2018, OR27-3, 2018 | | 2018 |
Development of a new generation of integrin targeting drugs for the treatment of immune-mediated diseases G Weitz-Schmidt, R Mancuso, M Huerzeler, S Kraehenbuehl, G Schneider, ... Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018 | | 2018 |
Identification and characterization of novel αLβ2 inhibitors and their differentiation from known inhibitors R Mancuso University_of_Basel, 2016 | | 2016 |
Small molecule lfa-1 inhibitors W Breitenstein, M Huerzeler, T Kelly, R MANCUSO, G Schneider, ... | | 2015 |
OR27-3 G Weitz-Schmidt, R Mancuso, M Huerzeler, S Kraehenbuehl, G Schneider, ... | | |