Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity Y Guo, YQ Xie, M Gao, Y Zhao, F Franco, M Wenes, I Siddiqui, ... Nature immunology 22 (6), 746-756, 2021 | 278 | 2021 |
Neoantigen vaccine delivery for personalized anticancer immunotherapy Y Guo, K Lei, L Tang Frontiers in immunology 9, 1499, 2018 | 166 | 2018 |
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy K Lei, A Kurum, M Kaynak, L Bonati, Y Han, V Cencen, M Gao, YQ Xie, ... Nature biomedical engineering 5 (12), 1411-1425, 2021 | 157 | 2021 |
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases Y Zhao, J Chen, M Andreatta, B Feng, YQ Xie, M Wenes, Y Wang, M Gao, ... Nature Biotechnology, 1-12, 2024 | 71 | 2024 |
High-temperature cultivation of recombinant Pichia pastorisincreases endoplasmic reticulum stress and decreases production of human interleukin-10 Y Zhong, L Yang, Y Guo, F Fang, D Wang, R Li, M Jiang, W Kang, J Ma, ... Microbial Cell Factories 13, 1-10, 2014 | 61 | 2014 |
A manganese phosphate nanocluster activates the cGAS‐STING pathway for enhanced cancer immunotherapy M Gao, YQ Xie, K Lei, Y Zhao, A Kurum, S Van Herck, Y Guo, X Hu, ... Advanced Therapeutics 4 (8), 2100065, 2021 | 49 | 2021 |
Switchable immune modulator for tumor-specific activation of anticancer immunity Y Zhao, YQ Xie, S Van Herck, S Nassiri, M Gao, Y Guo, L Tang Science advances 7 (37), eabg7291, 2021 | 37 | 2021 |
Engineering cancer vaccines using stimuli-responsive biomaterials Y Zhao, Y Guo, L Tang Nano Research 11, 5355-5371, 2018 | 36 | 2018 |
STAT3 and NF-κB are simultaneously suppressed in dendritic cells in lung cancer R Li, F Fang, M Jiang, C Wang, J Ma, W Kang, Q Zhang, Y Miao, D Wang, ... Scientific Reports 7 (1), 45395, 2017 | 34 | 2017 |
Improved the expression level of active transglutaminase by directional increasing copy of mtg gene in Pichia pastoris X Song, C Shao, Y Guo, Y Wang, J Cai BMC biotechnology 19, 1-9, 2019 | 20 | 2019 |
Elimination of N-glycosylation by site mutation further prolongs the half-life of IFN-α/Fc fusion proteins expressed in Pichia pastoris H Jia, Y Guo, X Song, C Shao, J Wu, J Ma, M Shi, Y Miao, R Li, D Wang, ... Microbial cell factories 15, 1-9, 2016 | 20 | 2016 |
The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer B Feng, Z Bai, X Zhou, Y Zhao, YQ Xie, X Huang, Y Liu, T Enbar, R Li, ... Nature 634 (8034), 712-720, 2024 | 19 | 2024 |
Purification and characterization of human IL-10/Fc fusion protein expressed in Pichia pastoris Y Guo, W Kang, Y Zhong, R Li, G Li, Y Shen, S Hu, J Sun, W Xiao Protein Expression and Purification 83 (2), 152-156, 2012 | 19 | 2012 |
Balancing the expression and production of a heterodimeric protein: recombinant agkisacutacin as a novel antithrombotic drug candidate Y Guo, J Wu, H Jia, W Chen, C Shao, L Zhao, J Ma, R Li, Y Zhong, F Fang, ... Scientific Reports 5 (1), 11730, 2015 | 14 | 2015 |
PAX5 interacts with RIP2 to promote NF-κB activation and drug-resistance in B-lymphoproliferative disorders D Wang, J Chen, R Li, G Wu, Z Sun, Z Wang, Z Zhai, F Fang, Y Guo, ... Journal of Cell Science 129 (11), 2261-2272, 2016 | 13 | 2016 |
Production and characterization of recombinant 9 and 15 kDa granulysin by fed-batch fermentation in Pichia pastoris Y Guo, G Luan, G Shen, L Wu, H Jia, Y Zhong, R Li, G Li, Y Shen, J Sun, ... Applied microbiology and biotechnology 97, 7669-7677, 2013 | 13 | 2013 |
Biotransformation of menadione to its prenylated derivative MK-3 using recombinant Pichia pastoris Z Li, G Zhao, H Liu, Y Guo, H Wu, X Sun, X Wu, Z Zheng Journal of Industrial Microbiology and Biotechnology 44 (7), 973-985, 2017 | 12 | 2017 |
The expression and characterization of functionally active soluble CD83 by Pichia pastoris using high-density fermentation Y Guo, R Li, X Song, Y Zhong, C Wang, H Jia, L Wu, D Wang, F Fang, ... PLoS One 9 (2), e89264, 2014 | 12 | 2014 |
A magnetic nanovaccine enhances cancer immunotherapy Y Guo, L Tang ACS central science 5 (5), 747-749, 2019 | 11 | 2019 |
Development of IL-15/IL-15Rα sushi domain-IgG4 Fc complexes in Pichia pastoris with potent activities and prolonged half-lives H Xu, M Shi, C Shao, H Li, J Wu, Y Yu, F Fang, Y Guo, W Xiao Microbial Cell Factories 20 (1), 115, 2021 | 9 | 2021 |