A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ... Nature neuroscience 22 (12), 2087-2097, 2019 | 818 | 2019 |
Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows E Denisenko, BB Guo, M Jones, R Hou, L De Kock, T Lassmann, D Poppe, ... Genome biology 21, 1-25, 2020 | 513 | 2020 |
Transcriptional signature in microglia associated with Aβ plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature communications 12 (1), 3015, 2021 | 236 | 2021 |
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution CA Herring, RK Simmons, S Freytag, D Poppe, JJD Moffet, J Pflueger, ... Cell 185 (23), 4428-4447. e28, 2022 | 124 | 2022 |
Comprehensive evaluation of deconvolution methods for human brain gene expression GJ Sutton, D Poppe, RK Simmons, K Walsh, U Nawaz, R Lister, ... Nature Communications 13 (1), 1358, 2022 | 94 | 2022 |
Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood SM Clinton, ME Glover, A Maltare, AM Laszczyk, SJ Mehi, RK Simmons, ... Brain research 1527, 1-14, 2013 | 84 | 2013 |
DNA methylation markers in the postnatal developing rat brain RK Simmons, SA Stringfellow, ME Glover, AA Wagle, SM Clinton Brain research 1533, 26-36, 2013 | 63 | 2013 |
DNA methylation in the developing hippocampus and amygdala of anxiety-prone versus risk-taking rats RK Simmons, JL Howard, DN Simpson, H Akil, SM Clinton Developmental neuroscience 34 (1), 58-67, 2012 | 51 | 2012 |
Maternal style selectively shapes amygdalar development and social behavior in rats genetically prone to high anxiety JL Cohen, ME Glover, PC Pugh, AD Fant, RK Simmons, H Akil, IA Kerman, ... Developmental neuroscience 37 (3), 203-214, 2015 | 44 | 2015 |
Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research KS Montgomery, RK Simmons, G Edwards Iii, MM Nicolle, MA Gluck, ... Neurobiology of aging 32 (7), 1273-1285, 2011 | 34 | 2011 |
Altered DNA methylation in the developing brains of rats genetically prone to high versus low anxiety CR McCoy, ME Glover, LT Flynn, RK Simmons, JL Cohen, T Ptacek, ... Journal of Neuroscience 39 (16), 3144-3158, 2019 | 27 | 2019 |
A single cell brain atlas in human Alzheimer’s disease A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ... Biorxiv, 628347, 2019 | 14 | 2019 |
Mouse and human microglial phenotypes in Alzheimer’s disease are controlled by amyloid plaque phagocytosis through Hif1α A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... bioRxiv, 639054, 2019 | 9 | 2019 |
Systematic bias assessment in solid tissue 10x scRNA-seq workflows E Denisenko, BB Guo, M Jones, R Hou, L De Kock, T Lassmann, D Poppe, ... BioRxiv, 832444, 2019 | 8 | 2019 |
Embryonic stem cell-derived neurons as a model system for epigenome maturation during development S Martin, D Poppe, N Olova, C O’Leary, E Ivanova, J Pflueger, J Dechka, ... Genes 14 (5), 957, 2023 | 1 | 2023 |
Update regulator guidance to show that animal research really is no longer king L Marshall, R Simmons, G Sower Nature 633 (8029), 286, 2024 | | 2024 |
Embryonic Stem Cell-Derived Neurons as a Model System for Epigenome Maturation during Development. Genes 2023, 14, 957 S Martin, D Poppe, N Olova, C O’Leary, E Ivanova, J Pflueger, J Dechka, ... | | 2023 |
Transcriptional signature in microglia associated with A? plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature Research, 2021 | | 2021 |
Investigating epigenetic regulation of gene expression at singlenucleus resolution in development and neurodevelopmental disorders R Simmons | | 2021 |
Epigenetic Markers in the Developing Postnatal Brain RK Simmons | | 2013 |