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Kaela Kelly
Kaela Kelly
Verified email at duke.edu
Title
Cited by
Cited by
Year
Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity
APT Nguyen, E Tsika, K Kelly, N Levine, X Chen, AB West, S Boularand, ...
Proceedings of the National Academy of Sciences 117 (29), 17296-17307, 2020
612020
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain
E Xu, R Boddu, HA Abdelmotilib, A Sokratian, K Kelly, Z Liu, N Bryant, ...
Molecular Neurodegeneration 17, 1-19, 2022
492022
The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition
K Kelly, S Wang, R Boddu, Z Liu, O Moukha-Chafiq, C Augelli-Szafran, ...
Experimental neurology 309, 1-13, 2018
462018
Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia
A Sokratian, J Ziaee, K Kelly, A Chang, N Bryant, S Wang, E Xu, JY Li, ...
Acta neuropathologica 141, 547-564, 2021
292021
Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein
CF Brzozowski, BA Hijaz, V Singh, NZ Gcwensa, K Kelly, ES Boyden, ...
Acta Neuropathologica Communications 9, 1-18, 2021
212021
Pharmacodynamic biomarkers for emerging LRRK2 therapeutics
K Kelly, AB West
Frontiers in Neuroscience 14, 567352, 2020
182020
Exosome markers of LRRK2 kinase inhibition
S Wang, K Kelly, JM Brotchie, JB Koprich, AB West
npj Parkinson's Disease 6 (1), 32, 2020
152020
Evaluation of current methods to detect cellular leucine-rich repeat kinase 2 (LRRK2) kinase activity
B Fernández, VG Chittoor-Vinod, JH Kluss, K Kelly, N Bryant, ...
Journal of Parkinson's disease 12 (5), 1423-1447, 2022
102022
Genetic background influences LRRK2-mediated Rab phosphorylation in the rat brain
K Kelly, A Chang, L Hastings, H Abdelmotilib, AB West
Brain research 1759, 147372, 2021
102021
Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegeneration
L Hastings, A Sokratian, DJ Apicco, CM Stanhope, L Smith, WD Hirst, ...
Brain Communications 4 (2), fcac042, 2022
22022
Pathologic α-Synuclein Species Activate LRRK2 in Pro-Inflammatory Monocyte and Macrophage Responses
E Xu, R Boddu, HA Abdelmotilib, K Kelly, A Sokratian, AS Harms, ...
bioRxiv, 2020.05. 04.077065, 2020
12020
Predictive Markers of LRRK2 Inhibition in Biofluids
S Wang, K Kelly, N Schussler, S Boularand, L Dubois, F Hsieh, ...
Available at SSRN 3466981, 2019
12019
BRAIN COMMUNICATIONS AIN COMMUNICATIONS
L Hastings, A Sokratian, DJ Apicco, CM Stanhope, L Smith, WD Hirst, ...
2022
Pharmacodynamic Markers of LRRK2 Inhibition in Biofluids
S Wang, K Kelly, N Schussler, S Boularand, L Dubois, F Hsieh, ...
bioRxiv, 2020.01. 28.923557, 2020
2020
Pharmacodynamic Responses and Efficacies Associated with LRRK2 Inhibition
KJ Kelly
The University of Alabama at Birmingham, 2020
2020
Investigation of Aggregative Properties of the Antimicrobial Peptide LL‐37 by Dynamic Light Scattering (DLS) and Electrophoretic Shift Mobility Assay (EMSA)
K Kelly, R Zachary, M Craig
The FASEB Journal 29, 564.6, 2015
2015
Impact of Birth Outcomes and Genetic Variation on White Matter Microstructure in Neonates
K Kelly, S Jha, R Steiner, J Bullins, K Xia, F Zou, M Ahn, H Zhu, M Styner, ...
NEUROPSYCHOPHARMACOLOGY 39, S233-S233, 2014
2014
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Articles 1–17