Fisetin attenuates myocardial ischemia-reperfusion injury by activating the reperfusion injury salvage kinase (RISK) signaling pathway K Shanmugam, SR Boovarahan, P Prem, B Sivakumar, GA Kurian Frontiers in Pharmacology 12, 566470, 2021 | 33 | 2021 |
Attenuation of cardiac ischemia-reperfusion injury by sodium thiosulfate is partially dependent on the effect of cystathione beta synthase in the myocardium S Kannan, SR Boovarahan, J Rengaraju, P Prem, GA Kurian Cell Biochemistry and Biophysics 77, 261-272, 2019 | 17 | 2019 |
Recent advances in potential of Fisetin in the management of myocardial ischemia-reperfusion injury–A systematic review PN Prem, B Sivakumar, SR Boovarahan, GA Kurian Phytomedicine 101, 154123, 2022 | 15 | 2022 |
Fisetin attenuates renal ischemia/reperfusion injury by improving mitochondrial quality, reducing apoptosis and oxidative stress PN Prem, GA Kurian Naunyn-Schmiedeberg's Archives of Pharmacology 395 (5), 547-561, 2022 | 15 | 2022 |
FIsetin preserves interfibrillar mitochondria to protect against myocardial ischemia-reperfusion injury K Shanmugam, PN Prem, SR Boovarahan, B Sivakumar, GA Kurian Cell Biochemistry and Biophysics 80 (1), 123-137, 2022 | 14 | 2022 |
High-fat diet increased oxidative stress and mitochondrial dysfunction induced by renal ischemia-reperfusion injury in rat PN Prem, GA Kurian Frontiers in Physiology 12, 715693, 2021 | 14 | 2021 |
Inhibition of PI3K/mTOR/KATP channel blunts sodium thiosulphate preconditioning mediated cardioprotection against ischemia–reperfusion injury SR Boovarahan, H Venkatasubramanian, N Sharma, S Venkatesh, ... Archives of Pharmacal Research 44 (6), 605-620, 2021 | 8 | 2021 |
Hydrogen sulfide postconditioning rendered cardioprotection against myocardial ischemia-reperfusion injury is compromised in rats with diabetic cardiomyopathy. M Ansari, PN Prem, GA Kurian Microvascular Research 141, 104322, 2022 | 7 | 2022 |
Diabetic cardiomyopathy attenuated the protective effect of ischaemic post-conditioning against ischaemia-reperfusion injury in the isolated rat heart model GA Kurian, M Ansari, PN Prem Archives of Physiology and Biochemistry 129 (3), 711-722, 2023 | 6 | 2023 |
Fisetin ameliorates ischemia re-oxygenation injury in H9c2 cardiomyocytes via targeting the PI3K signalling pathway B Sivakumar, SR Boovarahan, PN Prem, GA Kurian Phytomedicine Plus 1 (3), 100094, 2021 | 4 | 2021 |
CABG Patients Develop Global DNA Hypermethylation, That Negatively Affect the Mitochondrial Function and Promote Post-Surgical Cognitive Decline: A Proof of Concept in Small Cohort SR Boovarahan, SB Kale, PN Prem, S Ravindran, A Arthanarisami, ... Journal of Clinical Medicine 12 (12), 4146, 2023 | 3 | 2023 |
High-fat diet-induced mitochondrial dysfunction is associated with loss of protection from ischemic preconditioning in renal ischemia reperfusion PN Prem, DR Chellappan, GA Kurian Pflügers Archiv-European Journal of Physiology 475 (5), 637-653, 2023 | 3 | 2023 |
Evaluating the effects of carbon monoxide releasing molecule-2 against myocardial ischemia–reperfusion injury in ovariectomized female rats A Kumar, SR Boovarahan, PN Prem, M Ramanathan, DR Chellappan, ... Naunyn-Schmiedeberg's Archives of Pharmacology 394, 2103-2115, 2021 | 3 | 2021 |
Cardiac damage following renal ischemia reperfusion injury increased with excessive consumption of high fat diet but enhanced the cardiac resistance to reperfusion stress in rat PN Prem, GA Kurian Heliyon 9 (11), 2023 | 2 | 2023 |
Long-term administration of fisetin was not as effective as short term in ameliorating IR injury in isolated rat heart PN Prem, B Sivakumar, SR Boovarahan, GA Kurian Naunyn-schmiedeberg's Archives of Pharmacology 395 (7), 859-863, 2022 | 2 | 2022 |
Evaluation of prophylactic efficacy of sodium thiosulfate in combating I/R injury in rat brain: exploring its efficiency further in vascular calcified brain slice model K Baskaran, JT Johnson, PN Prem, S Ravindran, GA Kurian Naunyn-Schmiedeberg's Archives of Pharmacology 396 (10), 2587-2598, 2023 | 1 | 2023 |
Resveratrol-mediated cardioprotection against myocardial ischemia-reperfusion injury was revoked by statin-induced mitochondrial alterations R C. Vedarathinam, Y Rajkumar, P Vetriselvan, PN Prem, A Ganapathy, ... Drug and Chemical Toxicology 45 (5), 2276-2284, 2022 | 1 | 2022 |
Does cardiac impairment develop in ischemic renal surgery in rats depending on the reperfusion time? PN Prem, GA Kurian Heliyon 10 (10), 2024 | | 2024 |
DNA hypomethylation by fisetin preserves mitochondria functional genes and contributes to the protection of I/R rat heart SR Boovarahan, K Balu, P Prem, B Sivakumar, GA Kurian Functional & Integrative Genomics 23 (4), 325, 2023 | | 2023 |
Preparation of fisetin loaded mesoporous silica nanocarrier to attenuate ischemia reperfusion injury PN Prem, KK Balu, S Gandhi, GA Kurian Journal of Materials Research 38 (19), 4441-4453, 2023 | | 2023 |