Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome O Rom, Y Liu, Z Liu, Y Zhao, J Wu, A Ghrayeb, L Villacorta, Y Fan, ... Science translational medicine 12 (572), eaaz2841, 2020 | 140 | 2020 |
Discovery of ARD-2585 as an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer W Xiang, L Zhao, X Han, C Qin, B Miao, D McEachern, Y Wang, ... Journal of medicinal chemistry 64 (18), 13487-13509, 2021 | 93 | 2021 |
Strategies toward discovery of potent and orally bioavailable proteolysis targeting chimera degraders of androgen receptor for the treatment of prostate cancer X Han, L Zhao, W Xiang, C Qin, B Miao, D McEachern, Y Wang, ... Journal of medicinal chemistry 64 (17), 12831-12854, 2021 | 82 | 2021 |
Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional … S Zeng, L Wang, T Chen, Y Wang, H Mo, H Qu Analytica chimica acta 733, 38-47, 2012 | 68 | 2012 |
Repurposing azithromycin for neonatal neuroprotection JDE Barks, Y Liu, L Wang, MP Pai, FS Silverstein Pediatric research 86 (4), 444-451, 2019 | 35 | 2019 |
Monitoring batch-to-batch reproducibility using direct analysis in real time mass spectrometry and multivariate analysis: A case study on precipitation S Zeng, T Chen, L Wang, H Qu Journal of pharmaceutical and biomedical analysis 76, 87-95, 2013 | 33 | 2013 |
Development and optimization of SPE-HPLC-UV/ELSD for simultaneous determination of nine bioactive components in Shenqi Fuzheng Injection based on Quality by Design principles L Wang, H Qu Analytical and bioanalytical chemistry 408, 2133-2145, 2016 | 29 | 2016 |
EEDi-5285: An exceptionally potent, efficacious, and orally active small-molecule inhibitor of embryonic ectoderm development RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ... Journal of medicinal chemistry 63 (13), 7252-7267, 2020 | 27 | 2020 |
Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature S Mao, Z Chen, L Wang, DB Khadka, M Xin, P Li, SQ Zhang The Journal of Organic Chemistry 84 (1), 463-471, 2018 | 27 | 2018 |
Direct analysis in real time mass spectrometry, a process analytical technology tool for real-time process monitoring in botanical drug manufacturing L Wang, S Zeng, T Chen, H Qu Journal of Pharmaceutical and Biomedical Analysis 91, 202-209, 2014 | 25 | 2014 |
A mussel-inspired hybrid copolymer adhered to chitosan-coated micro-sized carbon fiber aerogels for highly efficient nanoparticle scavenging RL Liu, S Mao, Y Wang, L Wang, YH Ge, XY Xu, Q Fu Environmental Science: Nano 4 (11), 2164-2174, 2017 | 23 | 2017 |
β-Cyclodextrin anchoring onto pericarpium granati-derived magnetic mesoporous carbon for selective capture of lopid in human serum and pharmaceutical wastewater samples RL Liu, ZQ Zhang, WH Jing, L Wang, ZM Luo, RM Chang, AG Zeng, W Du, ... Materials Science and Engineering: C 62, 605-613, 2016 | 21 | 2016 |
Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis Y Liu, Y Zhao, Y Shukha, H Lu, L Wang, Z Liu, C Liu, Y Zhao, H Wang, ... Cell reports 36 (4), 2021 | 19 | 2021 |
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis O Rom, Y Liu, AC Finney, A Ghrayeb, Y Zhao, Y Shukha, L Wang, ... Redox biology 52, 102313, 2022 | 17 | 2022 |
A new polymorphic form and polymorphic transformation of loratadine R Chang, Q Fu, P Yu, L Wang, Y Li, W Du, C Chang, A Zeng RSC advances 6 (88), 85063-85073, 2016 | 16 | 2016 |
On-line coupling of macroporous resin column chromatography with direct analysis in real time mass spectrometry utilizing a surface flowing mode sample holder S Zeng, L Wang, T Chen, H Qu Analytica Chimica Acta 811, 43-50, 2014 | 16 | 2014 |
Discovery of EEDi-5273 as an exceptionally potent and orally efficacious EED inhibitor capable of achieving complete and persistent tumor regression RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ... Journal of medicinal chemistry 64 (19), 14540-14556, 2021 | 15 | 2021 |
Optimization of eliglustat-based glucosylceramide synthase inhibitors as substrate reduction therapy for gaucher disease type 3 MW Wilson, L Shu, V Hinkovska-Galcheva, Y Jin, W Rajeswaran, A Abe, ... ACS chemical neuroscience 11 (20), 3464-3473, 2020 | 15 | 2020 |
Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer X Han, L Zhao, W Xiang, B Miao, C Qin, M Wang, T Xu, D McEachern, ... Journal of Medicinal Chemistry 66 (13), 8822-8843, 2023 | 14 | 2023 |
Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling S Mao, K Luo, L Wang, HY Zhao, A Shergalis, M Xin, N Neamati, Y Jin, ... Organic letters 21 (7), 2365-2368, 2019 | 14 | 2019 |