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Lu Wang
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Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome
O Rom, Y Liu, Z Liu, Y Zhao, J Wu, A Ghrayeb, L Villacorta, Y Fan, ...
Science translational medicine 12 (572), eaaz2841, 2020
1402020
Discovery of ARD-2585 as an exceptionally potent and orally active PROTAC degrader of androgen receptor for the treatment of advanced prostate cancer
W Xiang, L Zhao, X Han, C Qin, B Miao, D McEachern, Y Wang, ...
Journal of medicinal chemistry 64 (18), 13487-13509, 2021
932021
Strategies toward discovery of potent and orally bioavailable proteolysis targeting chimera degraders of androgen receptor for the treatment of prostate cancer
X Han, L Zhao, W Xiang, C Qin, B Miao, D McEachern, Y Wang, ...
Journal of medicinal chemistry 64 (17), 12831-12854, 2021
822021
Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional …
S Zeng, L Wang, T Chen, Y Wang, H Mo, H Qu
Analytica chimica acta 733, 38-47, 2012
682012
Repurposing azithromycin for neonatal neuroprotection
JDE Barks, Y Liu, L Wang, MP Pai, FS Silverstein
Pediatric research 86 (4), 444-451, 2019
352019
Monitoring batch-to-batch reproducibility using direct analysis in real time mass spectrometry and multivariate analysis: A case study on precipitation
S Zeng, T Chen, L Wang, H Qu
Journal of pharmaceutical and biomedical analysis 76, 87-95, 2013
332013
Development and optimization of SPE-HPLC-UV/ELSD for simultaneous determination of nine bioactive components in Shenqi Fuzheng Injection based on Quality by Design principles
L Wang, H Qu
Analytical and bioanalytical chemistry 408, 2133-2145, 2016
292016
EEDi-5285: An exceptionally potent, efficacious, and orally active small-molecule inhibitor of embryonic ectoderm development
RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ...
Journal of medicinal chemistry 63 (13), 7252-7267, 2020
272020
Synthesis of Aryl Trimethylstannane via BF3·OEt2-Mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature
S Mao, Z Chen, L Wang, DB Khadka, M Xin, P Li, SQ Zhang
The Journal of Organic Chemistry 84 (1), 463-471, 2018
272018
Direct analysis in real time mass spectrometry, a process analytical technology tool for real-time process monitoring in botanical drug manufacturing
L Wang, S Zeng, T Chen, H Qu
Journal of Pharmaceutical and Biomedical Analysis 91, 202-209, 2014
252014
A mussel-inspired hybrid copolymer adhered to chitosan-coated micro-sized carbon fiber aerogels for highly efficient nanoparticle scavenging
RL Liu, S Mao, Y Wang, L Wang, YH Ge, XY Xu, Q Fu
Environmental Science: Nano 4 (11), 2164-2174, 2017
232017
β-Cyclodextrin anchoring onto pericarpium granati-derived magnetic mesoporous carbon for selective capture of lopid in human serum and pharmaceutical wastewater samples
RL Liu, ZQ Zhang, WH Jing, L Wang, ZM Luo, RM Chang, AG Zeng, W Du, ...
Materials Science and Engineering: C 62, 605-613, 2016
212016
Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis
Y Liu, Y Zhao, Y Shukha, H Lu, L Wang, Z Liu, C Liu, Y Zhao, H Wang, ...
Cell reports 36 (4), 2021
192021
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis
O Rom, Y Liu, AC Finney, A Ghrayeb, Y Zhao, Y Shukha, L Wang, ...
Redox biology 52, 102313, 2022
172022
A new polymorphic form and polymorphic transformation of loratadine
R Chang, Q Fu, P Yu, L Wang, Y Li, W Du, C Chang, A Zeng
RSC advances 6 (88), 85063-85073, 2016
162016
On-line coupling of macroporous resin column chromatography with direct analysis in real time mass spectrometry utilizing a surface flowing mode sample holder
S Zeng, L Wang, T Chen, H Qu
Analytica Chimica Acta 811, 43-50, 2014
162014
Discovery of EEDi-5273 as an exceptionally potent and orally efficacious EED inhibitor capable of achieving complete and persistent tumor regression
RK Rej, C Wang, J Lu, M Wang, E Petrunak, KP Zawacki, D McEachern, ...
Journal of medicinal chemistry 64 (19), 14540-14556, 2021
152021
Optimization of eliglustat-based glucosylceramide synthase inhibitors as substrate reduction therapy for gaucher disease type 3
MW Wilson, L Shu, V Hinkovska-Galcheva, Y Jin, W Rajeswaran, A Abe, ...
ACS chemical neuroscience 11 (20), 3464-3473, 2020
152020
Discovery of ARD-2051 as a potent and orally efficacious proteolysis targeting chimera (PROTAC) degrader of androgen receptor for the treatment of advanced prostate cancer
X Han, L Zhao, W Xiang, B Miao, C Qin, M Wang, T Xu, D McEachern, ...
Journal of Medicinal Chemistry 66 (13), 8822-8843, 2023
142023
Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling
S Mao, K Luo, L Wang, HY Zhao, A Shergalis, M Xin, N Neamati, Y Jin, ...
Organic letters 21 (7), 2365-2368, 2019
142019
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