| Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras EL Jackson, N Willis, K Mercer, RT Bronson, D Crowley, R Montoya, ... Genes & development 15 (24), 3243-3248, 2001 | 2148 | 2001 |
| Impaired microRNA processing enhances cellular transformation and tumorigenesis MS Kumar, J Lu, KL Mercer, TR Golub, T Jacks Nature genetics 39 (5), 673-677, 2007 | 1809 | 2007 |
| Somatic activation of the K-ras oncogene causes early onset lung cancer in mice L Johnson, K Mercer, D Greenbaum, RT Bronson, D Crowley, ... Nature 410 (6832), 1111-1116, 2001 | 1343 | 2001 |
| Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects DA Tuveson, AT Shaw, NA Willis, DP Silver, EL Jackson, S Chang, ... Cancer cell 5 (4), 375-387, 2004 | 928 | 2004 |
| K-ras is an essential gene in the mouse with partial functional overlap with N-ras L Johnson, D Greenbaum, K Cichowski, K Mercer, E Murphy, E Schmitt, ... Genes & development 11 (19), 2468-2481, 1997 | 748 | 1997 |
| Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors AI McClatchey, I Saotome, K Mercer, D Crowley, JF Gusella, RT Bronson, ... Genes & development 12 (8), 1121-1133, 1998 | 455 | 1998 |
| p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis DG Kirsch, PM Santiago, E Di Tomaso, JM Sullivan, WS Hou, T Dayton, ... Science 327 (5965), 593-596, 2010 | 264 | 2010 |
| Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer TG Oliver, KL Mercer, LC Sayles, JR Burke, D Mendus, KS Lovejoy, ... Genes & development 24 (8), 837-852, 2010 | 242 | 2010 |
| Targeted deletion reveals an essential function for the telomere length regulator Trf1 J Karlseder, L Kachatrian, H Takai, K Mercer, S Hingorani, T Jacks, ... Molecular and cellular biology, 2003 | 236 | 2003 |
| The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer WA Freed-Pastor, LJ Lambert, ZA Ely, NB Pattada, A Bhutkar, G Eng, ... Cancer cell 39 (10), 1342-1360. e14, 2021 | 141 | 2021 |
| Identification of DHODH as a therapeutic target in small cell lung cancer L Li, SR Ng, CI Colón, BJ Drapkin, PP Hsu, Z Li, CS Nabel, CA Lewis, ... Science translational medicine 11 (517), eaaw7852, 2019 | 96 | 2019 |
| CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer SR Ng, WM Rideout III, EH Akama-Garren, A Bhutkar, KL Mercer, ... Proceedings of the National Academy of Sciences 117 (1), 513-521, 2020 | 71 | 2020 |
| ARF mutation accelerates pituitary tumor development in Rb+/− mice KY Tsai, D MacPherson, DA Rubinson, AY Nikitin, R Bronson, KL Mercer, ... Proceedings of the National Academy of Sciences 99 (26), 16865-16870, 2002 | 55 | 2002 |
| Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 R Romero, FJ Sánchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... Nature Cancer 1 (6), 589-602, 2020 | 46 | 2020 |
| Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF-β1 haploinsufficiency J Pandey, SM Umphress, Y Kang, J Angdisen, A Naumova, KL Mercer, ... Carcinogenesis 28 (12), 2589-2596, 2007 | 16 | 2007 |
| A prime editor mouse to model a broad spectrum of somatic mutations in vivo ZA Ely, N Mathey-Andrews, S Naranjo, SI Gould, KL Mercer, GA Newby, ... Nature biotechnology 42 (3), 424-436, 2024 | 15 | 2024 |
| A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells RS Patel, R Romero, EV Watson, AC Liang, M Burger, PMK Westcott, ... Nature communications 13 (1), 256, 2022 | 8 | 2022 |
| Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells M Melnikova, US Wauer, D Mendus, RA Hilger, TG Oliver, K Mercer, ... Molecular oncology 14 (4), 686-703, 2020 | 7 | 2020 |
| Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis W Freed-Pastor, L Lambert, Z Ely, N Pattada, A Bhutkar, A Jaeger, G Eng, ... Cancer Research 81 (22_Supplement), PO-063-PO-063, 2021 | | 2021 |
| Abstract IA17: The role of the senescence-associated secretory phenotype in cancer RS Patel, R Romero, AC Liang, EV Watson, M Burger, PMK Westcott, ... Cancer Immunology Research 9 (2_Supplement), IA17-IA17, 2021 | | 2021 |
