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Michael Holmes
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Toxoplasma gondii AP2IX-4 regulates gene expression during bradyzoite development
S Huang, MJ Holmes, JB Radke, DP Hong, TK Liu, MW White, ...
MSphere 2 (2), 10.1128/msphere. 00054-17, 2017
582017
Translational control in the latency of apicomplexan parasites
MJ Holmes, L da Silva Augusto, M Zhang, RC Wek, WJ Sullivan
Trends in parasitology 33 (12), 947-960, 2017
462017
Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress
J Misra, MJ Holmes, E T. Mirek, M Langevin, HG Kim, KR Carlson, ...
Nucleic acids research 49 (10), 5726-5742, 2021
342021
Silencing of tachyzoite enolase 2 alters nuclear targeting of bradyzoite enolase 1 in Toxoplasma gondii
M Holmes, U Liwak, I Pricop, X Wang, S Tomavo, S Ananvoranich
Microbes and infection 12 (1), 19-27, 2010
262010
The secreted acid phosphatase domain-containing GRA44 from Toxoplasma gondii is required for c-Myc induction in infected cells
WJ Blakely, MJ Holmes, G Arrizabalaga
Msphere 5 (1), 10.1128/msphere. 00877-19, 2020
212020
Toxoplasma gondii: inhibitory activity and encystation effect of securinine and pyrrolidine derivatives on Toxoplasma growth
M Holmes, AK Crater, B Dhudshia, AN Thadani, S Ananvoranich
Experimental parasitology 127 (2), 370-375, 2011
202011
m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii
MJ Holmes, LR Padgett, MS Bastos, WJ Sullivan Jr
PLoS Pathogens 17 (7), e1009335, 2021
192021
Simultaneous ribosome profiling of human host cells infected with Toxoplasma gondii
MJ Holmes, P Shah, RC Wek, WJ Sullivan Jr
Msphere 4 (3), 10.1128/msphere. 00292-19, 2019
162019
Sustained translational repression of lactate dehydrogenase 1 in Toxoplasma gondii bradyzoites is conferred by a small regulatory RNA hairpin
M Holmes, V Itaas, S Ananvoranich
The FEBS Journal 281 (22), 5077-5091, 2014
132014
Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii
LR Padgett, JM Lentini, MJ Holmes, KL Stilger, D Fu, WJ Sullivan Jr
PloS one 13 (1), e0189688, 2018
112018
Toxoplasma gondii AP2XII-2 contributes to transcriptional repression for sexual commitment
S Srivastava, MJ Holmes, MW White, WJ Sullivan Jr
Msphere 8 (2), e00606-22, 2023
102023
A transcriptional network required for bradyzoite development in Toxoplasma gondii is dispensable for recrudescent disease
SL Sokol-Borrelli, SM Reilly, MJ Holmes, SB Orchanian, MD Massmann, ...
Nature communications 14 (1), 6078, 2023
52023
Evaluation of the ability of short and long double-stranded RNAs to induce homologous gene silencing in the protozoan parasite, Toxoplasma gondii
AK Crater, A Cherry, M Holmes, D Kadri, S Ananvoranich
Am. J. Biomed. Sci 4 (1), 1-13, 2012
42012
mRNA cap-binding protein eIF4E1 is a novel regulator of Toxoplasma gondii latency
MJ Holmes, MS Bastos, V Dey, V Severo, RC Wek, WJ Sullivan Jr
bioRxiv, 2023
32023
Translation initiation factor eIF1. 2 promotes Toxoplasma stage conversion by regulating levels of key differentiation factors
F Wang, MJ Holmes, HJ Hong, P Thaprawat, G Kannan, MH Huynh, ...
bioRxiv, 2023.11. 03.565545, 2023
22023
Analysis of Translational Control in the Integrated Stress Response by Polysome Profiling
MJ Holmes, J Misra, RC Wek
The Integrated Stress Response: Methods and Protocols, 157-171, 2022
22022
Inhibitory Effects of Securinine and Related Compounds on Toxoplasma gondii and Mechanistic Insights into Transcript-Specific Translational Repression in the Bradyzoite …
MJ Holmes
University of Windsor, 2015
12015
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Articles 1–17