Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and … J Müller, A Aguado-Martínez, LM Ortega-Mora, J Moreno-Gonzalo, I Ferre, ... Journal of Antimicrobial Chemotherapy 72 (8), 2334-2341, 2017 | 48 | 2017 |
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection SLM Arnold, R Choi, MA Hulverson, DA Schaefer, S Vinayak, ... The Journal of Infectious Diseases 216 (1), 55-63, 2017 | 46 | 2017 |
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum KM Hennessey, IC Rogiers, HW Shih, MA Hulverson, R Choi, ... PLoS neglected tropical diseases 12 (8), e0006673, 2018 | 43 | 2018 |
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned R Choi, MA Hulverson, W Huang, RSR Vidadala, GR Whitman, LK Barrett, ... International journal for parasitology 50 (5), 413-422, 2020 | 40 | 2020 |
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis MA Hulverson, R Choi, SLM Arnold, DA Schaefer, A Hemphill, ... International journal for parasitology 47 (12), 753-763, 2017 | 33 | 2017 |
In vitro Studies of Transendothelial Migration for Biological and Drug Discovery AT Salminen, Z Allahyari, S Gholizadeh, MC McCloskey, R Ajalik, ... Frontiers in Medical Technology 2, 600616, 2020 | 28 | 2020 |
Development of 5-aminopyrazole-4-carboxamide-based bumped-kinase inhibitors for cryptosporidiosis therapy W Huang, MA Hulverson, R Choi, SLM Arnold, Z Zhang, MC McCloskey, ... Journal of medicinal chemistry 62 (6), 3135-3146, 2019 | 28 | 2019 |
Microvascular mimetics for the study of leukocyte–endothelial interactions TS Khire, AT Salminen, H Swamy, KS Lucas, MC McCloskey, RE Ajalik, ... Cellular and Molecular Bioengineering 13, 125-139, 2020 | 21 | 2020 |
5-Aminopyrazole-4-carboxamide-based compounds prevent the growth of Cryptosporidium parvum W Huang, R Choi, MA Hulverson, Z Zhang, MC McCloskey, DA Schaefer, ... Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00020-17, 2017 | 18 | 2017 |
The modular µSiM: a mass produced, rapidly assembled, and reconfigurable platform for the study of barrier tissue models in vitro MC McCloskey, P Kasap, SD Ahmad, SH Su, K Chen, M Mansouri, ... Advanced healthcare materials 11 (18), 2200804, 2022 | 15 | 2022 |
The modular µSiM reconfigured: integration of microfluidic capabilities to study in vitro barrier tissue models under flow M Mansouri, A Ahmed, SD Ahmad, MC McCloskey, IM Joshi, TR Gaborski, ... Advanced healthcare materials 11 (21), 2200802, 2022 | 14 | 2022 |
Pharmacokinetics and in vivo efficacy of pyrazolopyrimidine, pyrrolopyrimidine, and 5-aminopyrazole-4-carboxamide bumped kinase inhibitors against toxoplasmosis MA Hulverson, I Bruzual, EV McConnell, W Huang, RSR Vidadala, R Choi, ... The Journal of Infectious Diseases 219 (9), 1464-1473, 2019 | 12 | 2019 |
The influence of acetylcholinesterase on anxiety-and depression-like behaviors in fluoxetine-treated male mice MC McCloskey, TJ Young, SM Anderson Bios 88 (1), 29-38, 2017 | 12 | 2017 |
Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic AT Salminen, J Tithof, Y Izhiman, EA Masters, MC McCloskey, ... Integrative Biology 12 (11), 275-289, 2020 | 11 | 2020 |
A tissue chip with integrated digital immunosensors: In situ brain endothelial barrier cytokine secretion monitoring SH Su, Y Song, A Stephens, M Situ, MC McCloskey, JL McGrath, ... Biosensors and Bioelectronics 224, 115030, 2023 | 10 | 2023 |
Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri MC McCloskey, S Shaheen, L Rabago, MA Hulverson, R Choi, LK Barrett, ... Scientific Reports 9 (1), 13567, 2019 | 10 | 2019 |
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads MA Hulverson, R Choi, MC McCloskey, GR Whitman, KK Ojo, ... ACS Infectious Diseases 7 (5), 1275-1282, 2021 | 9 | 2021 |
P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium SLM Arnold, R Choi, MA Hulverson, GR Whitman, MC McCloskey, ... The Journal of Infectious Diseases 220 (7), 1188-1198, 2019 | 9 | 2019 |
The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp E Fernández Álvaro, P Voong Vinh, C de Cozar, DR Willé, B Urones, ... Elife 11, e69798, 2022 | 8* | 2022 |
7 H-Pyrrolo [2, 3-d] pyrimidin-4-amine-based inhibitors of calcium-dependent protein kinase 1 have distinct inhibitory and oral pharmacokinetic characteristics compared with 1 … RSR Vidadala, M Golkowski, MA Hulverson, R Choi, MC McCloskey, ... ACS infectious diseases 4 (4), 516-522, 2018 | 8 | 2018 |