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Molly C. McCloskey
Molly C. McCloskey
University of Rochester
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Year
Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and …
J Müller, A Aguado-Martínez, LM Ortega-Mora, J Moreno-Gonzalo, I Ferre, ...
Journal of Antimicrobial Chemotherapy 72 (8), 2334-2341, 2017
482017
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
SLM Arnold, R Choi, MA Hulverson, DA Schaefer, S Vinayak, ...
The Journal of Infectious Diseases 216 (1), 55-63, 2017
462017
Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum
KM Hennessey, IC Rogiers, HW Shih, MA Hulverson, R Choi, ...
PLoS neglected tropical diseases 12 (8), e0006673, 2018
432018
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
R Choi, MA Hulverson, W Huang, RSR Vidadala, GR Whitman, LK Barrett, ...
International journal for parasitology 50 (5), 413-422, 2020
402020
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis
MA Hulverson, R Choi, SLM Arnold, DA Schaefer, A Hemphill, ...
International journal for parasitology 47 (12), 753-763, 2017
332017
In vitro Studies of Transendothelial Migration for Biological and Drug Discovery
AT Salminen, Z Allahyari, S Gholizadeh, MC McCloskey, R Ajalik, ...
Frontiers in Medical Technology 2, 600616, 2020
282020
Development of 5-aminopyrazole-4-carboxamide-based bumped-kinase inhibitors for cryptosporidiosis therapy
W Huang, MA Hulverson, R Choi, SLM Arnold, Z Zhang, MC McCloskey, ...
Journal of medicinal chemistry 62 (6), 3135-3146, 2019
282019
Microvascular mimetics for the study of leukocyte–endothelial interactions
TS Khire, AT Salminen, H Swamy, KS Lucas, MC McCloskey, RE Ajalik, ...
Cellular and Molecular Bioengineering 13, 125-139, 2020
212020
5-Aminopyrazole-4-carboxamide-based compounds prevent the growth of Cryptosporidium parvum
W Huang, R Choi, MA Hulverson, Z Zhang, MC McCloskey, DA Schaefer, ...
Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00020-17, 2017
182017
The modular µSiM: a mass produced, rapidly assembled, and reconfigurable platform for the study of barrier tissue models in vitro
MC McCloskey, P Kasap, SD Ahmad, SH Su, K Chen, M Mansouri, ...
Advanced healthcare materials 11 (18), 2200804, 2022
152022
The modular µSiM reconfigured: integration of microfluidic capabilities to study in vitro barrier tissue models under flow
M Mansouri, A Ahmed, SD Ahmad, MC McCloskey, IM Joshi, TR Gaborski, ...
Advanced healthcare materials 11 (21), 2200802, 2022
142022
Pharmacokinetics and in vivo efficacy of pyrazolopyrimidine, pyrrolopyrimidine, and 5-aminopyrazole-4-carboxamide bumped kinase inhibitors against toxoplasmosis
MA Hulverson, I Bruzual, EV McConnell, W Huang, RSR Vidadala, R Choi, ...
The Journal of Infectious Diseases 219 (9), 1464-1473, 2019
122019
The influence of acetylcholinesterase on anxiety-and depression-like behaviors in fluoxetine-treated male mice
MC McCloskey, TJ Young, SM Anderson
Bios 88 (1), 29-38, 2017
122017
Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic
AT Salminen, J Tithof, Y Izhiman, EA Masters, MC McCloskey, ...
Integrative Biology 12 (11), 275-289, 2020
112020
A tissue chip with integrated digital immunosensors: In situ brain endothelial barrier cytokine secretion monitoring
SH Su, Y Song, A Stephens, M Situ, MC McCloskey, JL McGrath, ...
Biosensors and Bioelectronics 224, 115030, 2023
102023
Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri
MC McCloskey, S Shaheen, L Rabago, MA Hulverson, R Choi, LK Barrett, ...
Scientific Reports 9 (1), 13567, 2019
102019
Repurposing Infectious Disease Hits as Anti-Cryptosporidium Leads
MA Hulverson, R Choi, MC McCloskey, GR Whitman, KK Ojo, ...
ACS Infectious Diseases 7 (5), 1275-1282, 2021
92021
P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium
SLM Arnold, R Choi, MA Hulverson, GR Whitman, MC McCloskey, ...
The Journal of Infectious Diseases 220 (7), 1188-1198, 2019
92019
The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp
E Fernández Álvaro, P Voong Vinh, C de Cozar, DR Willé, B Urones, ...
Elife 11, e69798, 2022
8*2022
7 H-Pyrrolo [2, 3-d] pyrimidin-4-amine-based inhibitors of calcium-dependent protein kinase 1 have distinct inhibitory and oral pharmacokinetic characteristics compared with 1 …
RSR Vidadala, M Golkowski, MA Hulverson, R Choi, MC McCloskey, ...
ACS infectious diseases 4 (4), 516-522, 2018
82018
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Articles 1–20