A Three-Dimensional Model of Lanosterol 14α-Demethylase of Candida albicans and Its Interaction with Azole Antifungals H Ji, W Zhang, Y Zhou, M Zhang, J Zhu, Y Song, J Lü, J Zhu Journal of medicinal chemistry 43 (13), 2493-2505, 2000 | 320 | 2000 |
Antifibrotic effects of matrine on in vitro and in vivo models of liver fibrosis in rats. JP Zhang, M Zhang, JP Zhou, FT Liu, B Zhou, WF Xie, C Guo Acta Pharmacologica Sinica 22 (2), 183-186, 2001 | 177 | 2001 |
Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14α-demethylase of fungi H Ji, W Zhang, M Zhang, M Kudo, Y Aoyama, Y Yoshida, C Sheng, ... Journal of medicinal chemistry 46 (4), 474-485, 2003 | 159 | 2003 |
IGF-1 regulation of type II collagen and MMP-13 expression in rat endplate chondrocytes via distinct signaling pathways M Zhang, Q Zhou, QQ Liang, CG Li, JD Holz, D Tang, TJ Sheu, TF Li, ... Osteoarthritis and cartilage 17 (1), 100-106, 2009 | 118 | 2009 |
Inhibition of β-catenin/B cell lymphoma 9 protein− protein interaction using α-helix–mimicking sulfono-γ-AApeptide inhibitors P Sang, M Zhang, Y Shi, C Li, S Abdulkadir, Q Li, H Ji, J Cai Proceedings of the National Academy of Sciences 116 (22), 10757-10762, 2019 | 82 | 2019 |
Rational design of selective small-molecule inhibitors for β-catenin/B-cell lymphoma 9 protein–protein interactions LR Hoggard, Y Zhang, M Zhang, V Panic, JA Wisniewski, H Ji Journal of the American Chemical Society 137 (38), 12249-12260, 2015 | 70 | 2015 |
Discovery of selective small-molecule inhibitors for the β-Catenin/T-Cell factor protein–protein interaction through the optimization of the acyl hydrazone moiety JL Catrow, Y Zhang, M Zhang, H Ji Journal of medicinal chemistry 58 (11), 4678-4692, 2015 | 67 | 2015 |
Effect of six flavonoids on proliferation of hepatic stellate cells in vitro. M Zhang, JP Zhang, HT Ji, JS Wang, DH Qian Acta Pharmacologica Sinica 21 (3), 253-256, 2000 | 64 | 2000 |
Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine QQ Liang, Q Zhou, M Zhang, W Hou, XJ Cui, CG Li, TF Li, Q Shi, YJ Wang Spine 33 (19), 2052-2058, 2008 | 63 | 2008 |
Targeting the Tcf4 G13ANDE17 Binding Site To Selectively Disrupt β-Catenin/T-Cell Factor Protein–Protein Interactions Z Huang, M Zhang, SD Burton, LN Katsakhyan, H Ji ACS chemical biology 9 (1), 193-201, 2014 | 62 | 2014 |
Rational design of small-molecule inhibitors for β-catenin/T-cell factor protein–protein interactions by bioisostere replacement B Yu, Z Huang, M Zhang, DR Dillard, H Ji ACS Chemical Biology 8 (3), 524-529, 2013 | 60 | 2013 |
Muscone protects vertebral end-plate degeneration by antiinflammatory property QQ Liang, M Zhang, Q Zhou, Q Shi, YJ Wang Clinical Orthopaedics and Related Research® 468 (6), 1600-1610, 2010 | 60 | 2010 |
Matrine inhibits production and actions of fibrogenic cytokines released by mouse peritoneal macrophages. JP Zhang, M Zhang, C Jin, B Zhou, WF Xie, C Guo, C Zhang, DH Qian Acta Pharmacologica Sinica 22 (8), 765-768, 2001 | 51 | 2001 |
Structure-based design of 1, 4-dibenzoylpiperazines as β-catenin/B-cell lymphoma 9 protein–protein interaction inhibitors JA Wisniewski, J Yin, KB Teuscher, M Zhang, H Ji ACS medicinal chemistry letters 7 (5), 508-513, 2016 | 45 | 2016 |
Structure-based optimization of small-molecule inhibitors for the β-catenin/b-cell lymphoma 9 protein–protein interaction M Zhang, Z Wang, Y Zhang, W Guo, H Ji Journal of medicinal chemistry 61 (7), 2989-3007, 2018 | 37 | 2018 |
High-throughput selectivity assays for small-molecule inhibitors of β-catenin/T-cell factor protein–protein interactions M Zhang, JL Catrow, H Ji ACS medicinal chemistry letters 4 (2), 306-311, 2013 | 37 | 2013 |
A versatile method to determine the cellular bioavailability of small-molecule inhibitors KB Teuscher, M Zhang, H Ji Journal of medicinal chemistry 60 (1), 157-169, 2017 | 31 | 2017 |
AlphaScreen selectivity assay for β-catenin/B-cell lymphoma 9 inhibitors M Zhang, JA Wisniewski, H Ji Analytical biochemistry 469, 43-53, 2015 | 30 | 2015 |
Optimization of peptidomimetics as selective inhibitors for the β-catenin/T-cell factor protein–protein interaction Z Wang, M Zhang, J Wang, H Ji Journal of medicinal chemistry 62 (7), 3617-3635, 2019 | 24 | 2019 |
Isoform of Vascular Endothelial Cell Growth Inhibitor (VEGI72–251) Increases Interleukin-2 Production by Activation of T Lymphocytes JJ Yao, M Zhang, XH Miao, P Zhao, SY Zhu, H Ding, ZT Qi Acta biochimica et biophysica Sinica 38 (4), 249-253, 2006 | 14 | 2006 |