关注
Bryan Mackowiak
Bryan Mackowiak
National Institute on Alcohol Abuse and Alcoholism
在 umaryland.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases
X Wang, Y He, B Mackowiak, B Gao
Gut 70 (4), 784-795, 2021
3372021
Mechanisms of xenobiotic receptor activation: Direct vs. indirect
B Mackowiak, H Wang
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016
1322016
The roles of xenobiotic receptors: beyond chemical disposition
B Mackowiak, J Hodge, S Stern, H Wang
Drug Metabolism and Disposition 46 (9), 1361-1371, 2018
1092018
Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells
D Li, B Mackowiak, TG Brayman, M Mitchell, L Zhang, SM Huang, H Wang
Biochemical pharmacology 98 (1), 190-202, 2015
572015
Identification of modulators that activate the constitutive androstane receptor from the Tox21 10K compound library
C Lynch, B Mackowiak, R Huang, L Li, S Heyward, S Sakamuru, H Wang, ...
Toxicological Sciences 167 (1), 282-292, 2019
332019
Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
J Ma, A Guillot, Z Yang, B Mackowiak, S Hwang, O Park, BJ Peiffer, ...
The Journal of Clinical Investigation 132 (14), 2022
312022
E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9
RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ...
Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022
302022
Mechanistic insights of phenobarbital-mediated activation of human but not mouse pregnane X receptor
L Li, MA Welch, Z Li, B Mackowiak, S Heyward, PW Swaan, H Wang
Molecular Pharmacology 96 (3), 345-354, 2019
282019
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression
Y Fu, B Mackowiak, D Feng, H Lu, Y Guan, T Lehner, H Pan, XW Wang, ...
Gut 72 (10), 1942-1958, 2023
212023
Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes
Y He, D Feng, S Hwang, B Mackowiak, X Wang, X Xiang, RM Rodrigues, ...
Journal of hepatology 75 (1), 163-176, 2021
202021
Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death, and lipolysis
SH Park, W Seo, MJ Xu, B Mackowiak, Y Lin, Y He, Y Fu, S Hwang, ...
Cellular and molecular gastroenterology and hepatology 15 (2), 281-306, 2023
172023
Hepatic injury and inflammation alter ethanol metabolism and drinking behavior
T Ren, B Mackowiak, Y Lin, Y Gao, J Niu, B Gao
Food and chemical toxicology 136, 111070, 2020
152020
Molecular basis of metabolism-mediated conversion of PK11195 from an antagonist to an agonist of the constitutive androstane receptor
B Mackowiak, L Li, MA Welch, D Li, JW Jones, S Heyward, MA Kane, ...
Molecular Pharmacology 92 (1), 75-87, 2017
132017
Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies
D Liang, L Li, C Lynch, B Mackowiak, WD Hedrich, Y Ai, Y Yin, S Heyward, ...
European journal of medicinal chemistry 179, 84-99, 2019
122019
Alcohol-associated liver disease
B Mackowiak, Y Fu, L Maccioni, B Gao
The Journal of Clinical Investigation 134 (3), 2024
82024
Mechanistic Analysis of an Extracellular Signal–Regulated Kinase 2–Interacting Compound That Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress
R Martinez, W Huang, R Samadani, B Mackowiak, G Centola, L Chen, ...
Journal of Pharmacology and Experimental Therapeutics 376 (1), 84-97, 2021
82021
High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis
B Mackowiak, L Li, C Lynch, A Ziman, S Heyward, M Xia, H Wang
Biochemical pharmacology 168, 224-236, 2019
82019
Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism
Y Fu, S Liu, RM Rodrigues, Y Han, C Guo, Z Zhu, Y He, B Mackowiak, ...
International journal of biological sciences 18 (11), 4341, 2022
72022
CITCO as an adjuvant facilitates CHOP-based lymphoma treatment in hCAR-transgenic mice
R Kurian, W Hedrich, B Mackowiak, L Li, H Wang
Cells 9 (11), 2520, 2020
52020
Alcohol metabolism in alcohol use disorder: a potential therapeutic target
T Lehner, B Gao, B Mackowiak
Alcohol and Alcoholism 59 (1), agad077, 2024
42024
系统目前无法执行此操作,请稍后再试。
文章 1–20