Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins P Venkatraman, R Wetzel, M Tanaka, N Nukina, AL Goldberg Molecular cell 14 (1), 95-104, 2004 | 521 | 2004 |
Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells P Venkatraman, TT Nguyen, M Sainlos, O Bilsel, S Chitta, B Imperiali, ... Nature chemical biology 3 (4), 222-228, 2007 | 111 | 2007 |
Puromycinsensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradation N Bhutani, P Venkatraman, AL Goldberg The EMBO journal 26 (5), 1385-1396, 2007 | 99 | 2007 |
The Role of Protein Dynamics in Thymidylate Synthase Catalysis: Variants of Conserved 2‘-Deoxyuridine 5‘-Monophosphate (dUMP)-Binding Tyr-261, Z Newby, TT Lee, RJ Morse, Y Liu, L Liu, P Venkatraman, DV Santi, ... Biochemistry 45 (24), 7415-7428, 2006 | 57 | 2006 |
A novel pocket in 14-3-3ɛ is required to mediate specific complex formation with cdc25C and to inhibit cell cycle progression upon activation of checkpoint pathways E Telles, AS Hosing, ST Kundu, P Venkatraman, SN Dalal Experimental cell research 315 (8), 1448-1457, 2009 | 44 | 2009 |
A novel role for the proteasomal chaperone PSMD 9 and hn RNPA 1 in enhancing IκBα degradation and NFκB activation–functional relevance of predicted PDZ domain–motif interaction I Sahu, N Sangith, M Ramteke, R Gadre, P Venkatraman The FEBS journal 281 (11), 2688-2709, 2014 | 37 | 2014 |
Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes N Bhutani, R Piccirillo, R Hourez, P Venkatraman, AL Goldberg Journal of Biological Chemistry 287 (21), 17471-17482, 2012 | 34 | 2012 |
Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein—Evidence for a common hot spot site at the interface and its functional … PP Nanaware, MP Ramteke, AK Somavarapu, P Venkatraman Proteins: Structure, Function, and Bioinformatics 82 (7), 1283-1300, 2014 | 33 | 2014 |
Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals AK Singh Gautam, S Balakrishnan, P Venkatraman PloS one 7 (4), e34864, 2012 | 25 | 2012 |
Identification of a novel ATPase activity in 14-3-3 proteins–Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies MP Ramteke, P Shelke, V Ramamoorthy, AK Somavarapu, AKS Gautam, ... FEBS letters 588 (1), 71-78, 2014 | 21 | 2014 |
From prediction to experimental validation: desmoglein 2 is a functionally relevant substrate of matriptase in epithelial cells and their reciprocal relationship is important … V Wadhawan, YA Kolhe, N Sangith, AKS Gautam, P Venkatraman Biochemical Journal 447 (1), 61-70, 2012 | 17 | 2012 |
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative … N Sangith, K Srinivasaraghavan, I Sahu, A Desai, S Medipally, ... FEBS open bio 4, 571-583, 2014 | 14 | 2014 |
Enhanced proteasomal activity is essential for long term survival and recurrence of innately radiation resistant residual glioblastoma cells J Rajendra, KK Datta, SBUD Farooqee, R Thorat, K Kumar, N Gardi, ... Oncotarget 9 (45), 27667, 2018 | 12 | 2018 |
Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation AK Somavarapu, S Balakrishnan, AKS Gautam, DS Palmer, ... BMC structural biology 14, 1-14, 2014 | 12 | 2014 |
The polybasic insert, the RBD of the SARS-CoV-2 spike protein, and the feline coronavirus–evolved or yet to evolve A Budhraja, S Pandey, S Kannan, CS Verma, P Venkatraman Biochemistry and Biophysics Reports 25, 100907, 2021 | 11 | 2021 |
Prion protein transcription is auto-regulated through dynamic interactions with G-quadruplex motifs in its own promoter P Pradhan, A Srivastava, J Singh, B Biswas, A Saini, I Siddique, P Kumari, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (3), 194479, 2020 | 11 | 2020 |
A novel determinant of PSMD9 PDZ binding guides the evolution of the first generation of super binding peptides M Harish, S Kannan, S Puttagunta, MR Pradhan, CS Verma, ... Biochemistry 58 (32), 3422-3433, 2019 | 11 | 2019 |
Role of Sug1, a 19S proteasome ATPase, in the transcription of MHC I and the atypical MHC II molecules, HLA-DM and HLA-DO Y Inostroza-Nieves, P Venkatraman, Z Zavala-Ruiz Immunology letters 147 (1-2), 67-74, 2012 | 11 | 2012 |
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics P Venkatraman, S Vemparala Scientific reports 8 (1), 12976, 2018 | 10 | 2018 |
Specificity in the interaction of natural products with their target proteins-a biochemical and structural insight P Venkatraman Mini Reviews in Medicinal Chemistry 10 (6), 540-549, 2010 | 10 | 2010 |