| Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory F Liu, M Day, LC Muniz, D Bitran, R Arias, R Revilla-Sanchez, S Grauer, ... Nature neuroscience 11 (3), 334-343, 2008 | 558 | 2008 |
| Phosphodiesterase 10A inhibitor activity in preclinical models of the positive, cognitive, and negative symptoms of schizophrenia SM Grauer, VL Pulito, RL Navarra, MP Kelly, C Kelley, R Graf, B Langen, ... Journal of Pharmacology and Experimental Therapeutics 331 (2), 574-590, 2009 | 296 | 2009 |
| ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1, 2, 4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive … F Liu, S Grauer, C Kelley, R Navarra, R Graf, G Zhang, PJ Atkinson, ... Journal of Pharmacology and Experimental Therapeutics 327 (3), 827-839, 2008 | 189 | 2008 |
| WAY-163909 [(7bR, 10aR)-1, 2, 3, 4, 8, 9, 10, 10a-octahydro-7bH-cyclopenta-[b][1, 4] diazepino [6, 7, 1hi] indole]: a novel 5-hydroxytryptamine 2C receptor-selective agonist … KL Marquis, AL Sabb, SF Logue, JA Brennan, MJ Piesla, TA Comery, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 486-496, 2007 | 188 | 2007 |
| Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist RH Ring, LE Schechter, SK Leonard, JM Dwyer, BJ Platt, R Graf, S Grauer, ... Neuropharmacology 58 (1), 69-77, 2010 | 168 | 2010 |
| Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents S Rosenzweig-Lipson, A Sabb, G Stack, P Mitchell, I Lucki, JE Malberg, ... Psychopharmacology 192, 159-170, 2007 | 138 | 2007 |
| The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders? SF Logue, SM Grauer, J Paulsen, R Graf, N Taylor, MA Sung, L Zhang, ... Molecular and Cellular Neuroscience 42 (4), 438-447, 2009 | 98 | 2009 |
| Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes MP Kelly, SF Logue, J Brennan, JP Day, S Lakkaraju, L Jiang, X Zhong, ... Proceedings of the National Academy of Sciences 107 (18), 8457-8462, 2010 | 93 | 2010 |
| Highly potent, selective, and orally active phosphodiesterase 10A inhibitors MS Malamas, Y Ni, J Erdei, H Stange, R Schindler, HJ Lankau, ... Journal of medicinal chemistry 54 (21), 7621-7638, 2011 | 83 | 2011 |
| Morphine induces an increase in extracellular serotonin in the rat diencephalon SBA SM Grauer, R Tao Brain Research 25 (599(2)), 277-82, 1992 | 46* | 1992 |
| Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist,(R)-N-(2-methyl-(4-indolyl-1-piperazinyl) ethyl)-N … WD Hirst, TH Andree, S Aschmies, WE Childers, TA Comery, LA Dawson, ... Journal of Pharmacology and Experimental Therapeutics 325 (1), 134-145, 2008 | 45 | 2008 |
| Intracerebral administration of metabotropic glutamate receptor agonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats SM Grauer, KL Marquis Psychopharmacology 141, 405-412, 1999 | 40 | 1999 |
| Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1 … C Ghiron, SN Haydar, S Aschmies, H Bothmann, C Castaldo, ... Journal of medicinal chemistry 53 (11), 4379-4389, 2010 | 37 | 2010 |
| WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics SM Grauer, R Graf, R Navarra, A Sung, SF Logue, G Stack, C Huselton, ... Psychopharmacology 204, 37-48, 2009 | 37 | 2009 |
| Novel triazines as potent and selective phosphodiesterase 10A inhibitors MS Malamas, H Stange, R Schindler, HJ Lankau, C Grunwald, B Langen, ... Bioorganic & medicinal chemistry letters 22 (18), 5876-5884, 2012 | 33 | 2012 |
| Tetrahydrocarbazole-based serotonin reuptake inhibitor/dopamine D2 partial agonists for the potential treatment of schizophrenia DP Rotella, GR McFarlane, A Greenfield, C Grosanu, AJ Robichaud, ... Bioorganic & medicinal chemistry letters 19 (19), 5552-5555, 2009 | 26 | 2009 |
| Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE … KL Marquis, TA Comery, F Jow, RL Navarra, SM Grauer, C Pulicicchio, ... Psychopharmacology 218, 635-647, 2011 | 24 | 2011 |
| The Synthesis and Biological Evaluation of Quinolyl-piperazinyl Piperidines as Potent Serotonin 5-HT1A Antagonists WE Childers Jr, LM Havran, M Asselin, JJ Bicksler, DC Chong, GT Grosu, ... Journal of medicinal chemistry 53 (10), 4066-4084, 2010 | 20 | 2010 |
| ADX47273: a novel metabotropic glutamate receptor 5 selective positive allosteric modulator with preclinical antipsychotic-like and pro-cognitive activities F Liu, S Grauer, C Kelley, R Navarra, R Graf, G Zhang, PJ Atkinson, ... Journal of Pharmacology and Experimental Therapeutics, 2008 | 19 | 2008 |
| WS-50030 [7-{4-[3-(1H-inden-3-yl) propyl] piperazin-1-yl}-1, 3-benzoxazol-2 (3H)-one]: a novel dopamine D2 receptor partial agonist/serotonin reuptake inhibitor with … JA Brennan, R Graf, SM Grauer, RL Navarra, CM Pulicicchio, ZA Hughes, ... Journal of Pharmacology and Experimental Therapeutics 332 (1), 190-201, 2010 | 17 | 2010 |
