Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2 AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ... Cell 183 (5), 1367-1382. e17, 2020 | 448 | 2020 |
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, ... Nature 594 (7862), 253-258, 2021 | 272 | 2021 |
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants M McCallum, AC Walls, KR Sprouse, JE Bowen, LE Rosen, HV Dang, ... Science 374 (6575), 1621-1626, 2021 | 250 | 2021 |
De novo design of modular and tunable protein biosensors A Quijano-Rubio, HW Yeh, J Park, H Lee, RA Langan, SE Boyken, ... Nature 591 (7850), 482-487, 2021 | 177 | 2021 |
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ... Cell 184 (21), 5432-5447. e16, 2021 | 144 | 2021 |
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine PS Arunachalam, Y Feng, U Ashraf, M Hu, AC Walls, VV Edara, ... Science translational medicine 14 (658), eabq4130, 2022 | 36 | 2022 |
Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein MA Tortorici, AC Walls, A Joshi, YJ Park, RT Eguia, MC Miranda, E Kepl, ... Cell 185 (13), 2279-2291. e17, 2022 | 33 | 2022 |
Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice L Grigoryan, A Lee, AC Walls, L Lai, B Franco, PS Arunachalam, Y Feng, ... npj Vaccines 7 (1), 55, 2022 | 30 | 2022 |
IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2 M Hale, J Netland, Y Chen, CD Thouvenel, KN Smith, LM Rich, ... Journal of Experimental Medicine 219 (9), e20220849, 2022 | 28 | 2022 |
Antigen-and scaffold-specific antibody responses to protein nanoparticle immunogens JC Kraft, MN Pham, L Shehata, M Brinkkemper, S Boyoglu-Barnum, ... Cell Reports Medicine 3 (10), 2022 | 23 | 2022 |
Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites CD Thouvenel, MF Fontana, J Netland, AT Krishnamurty, KK Takehara, ... Journal of Experimental Medicine 218 (4), e20200942, 2021 | 21 | 2021 |
Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, ... bioRxiv, 2021.02. 10.430696, 2021 | 20 | 2021 |
Schä fer AC Walls, MC Miranda A., Pham, MN, Greaney, A., Arunachalam, PS, Navarro, M.-J., Tortorici, MA …, 2021 | 16 | 2021 |
Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice AC Walls, LA VanBlargan, K Wu, A Choi, MJ Navarro, D Lee, L Avena, ... Cell Reports 40 (9), 2022 | 13 | 2022 |
Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses S Ols, K Lenart, RA Cerveira, MC Miranda, N Brunette, J Kochmann, ... Immunity 56 (10), 2425-2441. e14, 2023 | 11 | 2023 |
Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains JY Wang, A Khmelinskaia, W Sheffler, MC Miranda, A Antanasijevic, ... Proceedings of the National Academy of Sciences 120 (11), e2214556120, 2023 | 7 | 2023 |
De novo design of modular and tunable allosteric biosensors A Quijano-Rubio, HW Yeh, J Park, H Lee, RA Langan, SE Boyken, ... bioRxiv, 2020.07. 18.206946, 2020 | 7 | 2020 |
Accurate computational design of three-dimensional protein crystals Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MY Yaman, MJ Bick, ... Nature Materials 22 (12), 1556-1563, 2023 | 6 | 2023 |
Precisely patterned nanofibres made from extendable protein multiplexes NP Bethel, AJ Borst, F Parmeggiani, MJ Bick, TJ Brunette, H Nguyen, ... Nature Chemistry 15 (12), 1664-1671, 2023 | 6 | 2023 |
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8 A Roy, L Shi, A Chang, X Dong, A Fernandez, JC Kraft, J Li, VQ Le, ... Nature Communications 14 (1), 5660, 2023 | 4 | 2023 |