The future of antifungal drug therapy: novel compounds and targets C Mota Fernandes, D Dasilva, K Haranahalli, JB McCarthy, J Mallamo, ... Antimicrobial agents and chemotherapy 65 (2), 10.1128/aac. 01719-20, 2021 | 90 | 2021 |
High hydrostatic pressure activates gene expression through Msn2/4 stress transcription factors which are involved in the acquired tolerance by mild pressure precondition in … T Domitrovic, CM Fernandes, E Boy-Marcotte, E Kurtenbach FEBS letters 580 (26), 6033-6038, 2006 | 48 | 2006 |
Biological roles played by sphingolipids in dimorphic and filamentous fungi CM Fernandes, GH Goldman, M Del Poeta MBio 9 (3), 10.1128/mbio. 00642-18, 2018 | 45 | 2018 |
Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB Δ8‐desaturation and C9‐methylation are relevant to filamentous growth … CM Fernandes, PA De Castro, A Singh, FL Fonseca, MD Pereira, ... Molecular microbiology 102 (3), 488-505, 2016 | 41 | 2016 |
Fungal sphingolipids: role in the regulation of virulence and potential as targets for future antifungal therapies C Mota Fernandes, M Del Poeta Expert review of anti-infective therapy 18 (11), 1083-1092, 2020 | 37 | 2020 |
Metabolomics analysis identifies sphingolipids as key signaling moieties in appressorium morphogenesis and function in Magnaporthe oryzae XH Liu, S Liang, YY Wei, XM Zhu, L Li, PP Liu, QX Zheng, HN Zhou, ... MBio 10 (4), 10.1128/mbio. 01467-19, 2019 | 25 | 2019 |
Identification of antifungal compounds against multidrug-resistant Candida auris utilizing a high-throughput drug-repurposing screen YS Cheng, JS Roma, M Shen, C Mota Fernandes, PS Tsang, HE Forbes, ... Antimicrobial agents and chemotherapy 65 (4), 10.1128/aac. 01305-20, 2021 | 23 | 2021 |
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation NM Revie, KR Iyer, ME Maxson, J Zhang, S Yan, CM Fernandes, ... Nature communications 13 (1), 3634, 2022 | 22 | 2022 |
Psd2 pea defensin shows a preference for mimetic membrane rafts enriched with glucosylceramide and ergosterol VSG Amaral, CM Fernandes, MR Felício, AS Valle, PG Quintana, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1861 (4), 713-728, 2019 | 19 | 2019 |
The heat shock transcription factor HsfA is essential for thermotolerance and regulates cell wall integrity in Aspergillus fumigatus JHTM Fabri, MC Rocha, CM Fernandes, GF Persinoti, LNA Ries, ... Frontiers in microbiology 12, 656548, 2021 | 17 | 2021 |
Screening of chemical libraries for new antifungal drugs against Aspergillus fumigatus reveals sphingolipids are involved in the mechanism of action of miltefosine TF Dos Reis, MAC Horta, AC Colabardini, CM Fernandes, LP Silva, ... Mbio 12 (4), 10.1128/mbio. 01458-21, 2021 | 15 | 2021 |
A reliable assay to evaluate the virulence of Aspergillus nidulans using the alternative animal model Galleria mellonella (Lepidoptera) CM Fernandes, FL Fonseca, GH Goldman, MD Pereira, E Kurtenbach Bio-protocol 7 (11), e2329-e2329, 2017 | 14 | 2017 |
Biological roles played by sphingolipids in dimorphic and filamentous fungi. mBio 9: e00642-18 CM Fernandes, GH Goldman, M Del Poeta | 11 | 2018 |
Microdomain protein Nce102 is a local sensor of plasma membrane sphingolipid balance J Zahumenský, C Mota Fernandes, P Veselá, M Del Poeta, JB Konopka, ... Microbiology Spectrum 10 (4), e01961-22, 2022 | 9 | 2022 |
Vaccination with Live or Heat-Killed Aspergillus fumigatus ΔsglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis CM Fernandes, TG Normile, JHTM Fabri, VS Brauer, GR de S. Araújo, ... MBio 13 (5), e02328-22, 2022 | 8 | 2022 |
Regulation of sphingolipid synthesis by the G1/S transcription factor Swi4 GS Matos, JB Madeira, CM Fernandes, D Dasilva, CA Masuda, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2021 | 6 | 2021 |
Sphingolipid depletion suppresses UPR activation and promotes galactose hypersensitivity in yeast models of classic galactosemia FSA Pimentel, CM Machado, EA De-Souza, CM Fernandes, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (6), 166389, 2022 | 5 | 2022 |
The Heat Shock Transcription Factor HsfA Plays a Role in Membrane Lipids Biosynthesis Connecting Thermotolerance and Unsaturated Fatty Acid Metabolism in Aspergillus fumigatus JHTM Fabri, MC Rocha, CM Fernandes, JEM Campanella, AF Cunha, ... Microbiology Spectrum 11 (3), e01627-23, 2023 | 1 | 2023 |
Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats I Dib Ferreira Gremião, GR Pereira-Oliveira, SA Pereira, ML Corrêa, ... Microbiology Spectrum, e03967-23, 2024 | | 2024 |
Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans. PV Zande, C Gautier, N Kawar, C Maufrais, K Metzner, E Wash, AK Beach, ... bioRxiv, 2024.03. 05.583528, 2024 | | 2024 |