The Brazilian Zika virus strain causes birth defects in experimental models FR Cugola, IR Fernandes, FB Russo, BC Freitas, JLM Dias, ... Nature 534 (7606), 267-271, 2016 | 1411 | 2016 |
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals MC Marchetto, H Belinson, Y Tian, BC Freitas, C Fu, KC Vadodaria, ... Molecular psychiatry 22 (6), 820-835, 2017 | 406 | 2017 |
A human neurodevelopmental model for Williams syndrome T Chailangkarn, CA Trujillo, BC Freitas, B Hrvoj-Mihic, RH Herai, DX Yu, ... Nature 536 (7616), 338-343, 2016 | 200 | 2016 |
Paracrine signaling by glial cell–derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells BCG Freitas, B Gereben, M Castillo, I Kalló, A Zeöld, P Egri, Z Liposits, ... The Journal of clinical investigation 120 (6), 2206-2217, 2010 | 184 | 2010 |
Modeling the interplay between neurons and astrocytes in autism using human induced pluripotent stem cells FB Russo, BC Freitas, GC Pignatari, IR Fernandes, J Sebat, AR Muotri, ... Biological psychiatry 83 (7), 569-578, 2018 | 167 | 2018 |
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction ZN Zhang, BC Freitas, H Qian, J Lux, A Acab, CA Trujillo, RH Herai, ... Proceedings of the National Academy of Sciences 113 (12), 3185-3190, 2016 | 165 | 2016 |
Deubiquitination of type 2 iodothyronine deiodinase by von Hippel–Lindau protein–interacting deubiquitinating enzymes regulates thyroid hormone activation C Curcio-Morelli, AM Zavacki, M Christofollete, B Gereben, ... The Journal of clinical investigation 112 (2), 189-196, 2003 | 159 | 2003 |
Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity GDV Sagar, B Gereben, I Callebaut, JP Mornon, A Zeöld, WS da Silva, ... Molecular and cellular biology 27 (13), 4774-4783, 2007 | 127 | 2007 |
The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase AM Zavacki, R Arrojo e Drigo, BCG Freitas, M Chung, JW Harney, P Egri, ... Molecular and cellular biology 29 (19), 5339-5347, 2009 | 88 | 2009 |
A TRß-selective agonist confers resistance to dietinduced obesity BS Amorim, CB Ueta, BC Freitas, RJ Nassif, CH Gouveia, ... J Endocrinol 203, 291-299, 2009 | 60 | 2009 |
Genetic markers differentiating follicular thyroid carcinoma from benign lesions BCG Freitas, JM Cerutti Molecular and Cellular Endocrinology 321 (1), 77-85, 2010 | 52 | 2010 |
Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain C Fekete, BCG Freitas, A Zeöld, G Wittmann, A Kádár, Z Liposits, ... Endocrinology 148 (10), 4865-4874, 2007 | 46 | 2007 |
ABI3 ectopic expression reduces in vitro and in vivocell growth properties while inducing senescence FRM Latini, JP Hemerly, BCG Freitas, G Oler, GJ Riggins, JM Cerutti BMC cancer 11, 1-12, 2011 | 45 | 2011 |
Stem cells and modeling of autism spectrum disorders BCG Freitas, CA Trujillo, C Carromeu, M Yusupova, RH Herai, AR Muotri Experimental neurology 260, 33-43, 2014 | 38 | 2014 |
The use of iPSC technology for modeling Autism Spectrum Disorders FB Russo, A Brito, AM de Freitas, A Castanha, BC de Freitas, ... Neurobiology of Disease 130, 104483, 2019 | 32 | 2019 |
Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity M Castillo, BCG Freitas, ML Rosene, RA Drigo, R Grozovsky, RMB Maciel, ... Thyroid 20 (5), 545-553, 2010 | 32 | 2010 |
Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function JJ Kim, JN Savas, MT Miller, X Hu, C Carromeu, M Lavallée-Adam, ... PloS one 14 (2), e0212553, 2019 | 27 | 2019 |
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients S Stern, S Lau, A Manole, I Rosh, MM Percia, R Ben Ezer, MN Shokhirev, ... npj Parkinson's Disease 8 (1), 103, 2022 | 22 | 2022 |
The Na+/HCO3− co-transporter is protective during ischemia in astrocytes H Yao, P Azad, HW Zhao, J Wang, O Poulsen, BC Freitas, AR Muotri, ... Neuroscience 339, 329-337, 2016 | 22 | 2016 |
Modeling inflammation in autism spectrum disorders using stem cells BC Freitas, A Mei, APD Mendes, PCB Beltrão-Braga, MC Marchetto Frontiers in Pediatrics 6, 394, 2018 | 16 | 2018 |