| Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion RD Leone, L Zhao, JM Englert, IM Sun, MH Oh, IH Sun, ML Arwood, ... Science 366 (6468), 1013-1021, 2019 | 739 | 2019 |
| Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells K Sadtler, K Estrellas, BW Allen, MT Wolf, H Fan, AJ Tam, CH Patel, ... Science 352 (6283), 366-370, 2016 | 533 | 2016 |
| mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation KN Pollizzi, CH Patel, IH Sun, MH Oh, AT Waickman, J Wen, GM Delgoffe, ... The Journal of clinical investigation 125 (5), 2090-2108, 2015 | 407 | 2015 |
| Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells MH Oh, IH Sun, L Zhao, RD Leone, IM Sun, W Xu, SL Collins, AJ Tam, ... The Journal of clinical investigation 130 (7), 3865-3884, 2020 | 256 | 2020 |
| Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation KN Pollizzi, IH Sun, CH Patel, YC Lo, MH Oh, AT Waickman, AJ Tam, ... Nature immunology 17 (6), 704-711, 2016 | 245 | 2016 |
| Targeting metabolism to regulate immune responses in autoimmunity and cancer CH Patel, RD Leone, MR Horton, JD Powell Nature Reviews Drug Discovery 18 (9), 669-688, 2019 | 207 | 2019 |
| Acid suspends the circadian clock in hypoxia through inhibition of mTOR ZE Walton, CH Patel, RC Brooks, Y Yu, A Ibrahim-Hashim, M Riddle, ... Cell 174 (1), 72-87. e32, 2018 | 200 | 2018 |
| The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex EB Heikamp, CH Patel, S Collins, A Waickman, MH Oh, IH Sun, P Illei, ... Nature immunology 15 (5), 457-464, 2014 | 192 | 2014 |
| mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells IH Sun, MH Oh, L Zhao, CH Patel, ML Arwood, W Xu, AJ Tam, RL Blosser, ... The Journal of Immunology 201 (2), 481-492, 2018 | 122 | 2018 |
| Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease CH Patel, JD Powell Current opinion in immunology 46, 82-88, 2017 | 113 | 2017 |
| PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress MJ Ranek, KM Kokkonen-Simon, A Chen, BL Dunkerly-Eyring, MP Vera, ... Nature 566 (7743), 264-269, 2019 | 106 | 2019 |
| Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells EA Ananieva, CH Patel, CH Drake, JD Powell, SM Hutson Journal of Biological Chemistry 289 (27), 18793-18804, 2014 | 91 | 2014 |
| mTORC2 signaling selectively regulates the generation and function of tissue-resident peritoneal macrophages MH Oh, SL Collins, IH Sun, AJ Tam, CH Patel, ML Arwood, Y Chan-Li, ... Cell reports 20 (10), 2439-2454, 2017 | 53 | 2017 |
| Cellular size as a means of tracking mTOR activity and cell fate of CD4+ T cells upon antigen recognition KN Pollizzi, AT Waickman, CH Patel, IH Sun, JD Powell PloS one 10 (4), e0121710, 2015 | 51 | 2015 |
| The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity CK Baumgartner, H Ebrahimi-Nik, A Iracheta-Vellve, KM Hamel, ... Nature 622 (7984), 850-862, 2023 | 26 | 2023 |
| Lithium alters the morphology of neurites regenerating from cultured adult spiral ganglion neurons SM Shah, CH Patel, AS Feng, R Kollmar Hearing research 304, 137-144, 2013 | 24 | 2013 |
| Warburg meets epigenetics CH Patel, JD Powell Science 354 (6311), 419-420, 2016 | 11 | 2016 |
| GOT1 regulates CD8+ effector and memory T cell generation W Xu, CH Patel, L Zhao, IH Sun, MH Oh, IM Sun, RS Helms, J Wen, ... Cell reports 42 (1), 2023 | 10 | 2023 |
| GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation W Xu, CH Patel, J Alt, L Zhao, IH Sun, MH Oh, IM Sun, J Wen, RL Blosser, ... Nature 614 (7946), E1-E11, 2023 | 6 | 2023 |
| Targeting metabolism as a platform for inducing allograft tolerance in the absence of long-term immunosuppression CH Cheng, CF Lee, BC Oh, GJ Furtmüller, CH Patel, G Brandacher, ... Frontiers in immunology 11, 572, 2020 | 5 | 2020 |
