PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer P Carpinelli, R Ceruti, ML Giorgini, P Cappella, L Gianellini, V Croci, ... Molecular cancer therapeutics 6 (12), 3158-3168, 2007 | 286 | 2007 |
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile D Fancelli, J Moll, M Varasi, R Bravo, R Artico, D Berta, S Bindi, ... Journal of medicinal chemistry 49 (24), 7247-7251, 2006 | 240 | 2006 |
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity C Soncini, P Carpinelli, L Gianellini, D Fancelli, P Vianello, L Rusconi, ... Clinical Cancer Research 12 (13), 4080-4089, 2006 | 201 | 2006 |
Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase R Colombo, M Caldarelli, M Mennecozzi, ML Giorgini, F Sola, P Cappella, ... Cancer research 70 (24), 10255-10264, 2010 | 191 | 2010 |
Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition D Fancelli, D Berta, S Bindi, A Cameron, P Cappella, P Carpinelli, ... Journal of medicinal chemistry 48 (8), 3080-3084, 2005 | 175 | 2005 |
NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies B Valsasina, I Beria, C Alli, R Alzani, N Avanzi, D Ballinari, P Cappella, ... Molecular cancer therapeutics 11 (4), 1006-1016, 2012 | 124 | 2012 |
A novel method based on click chemistry, which overcomes limitations of cell cycle analysis by classical determination of BrdU incorporation, allowing multiplex antibody staining P Cappella, F Gasparri, M Pulici, J Moll Cytometry Part A: the journal of the International Society for Analytical …, 2008 | 118 | 2008 |
Cell cycle effects of gemcitabine P Cappella, D Tomasoni, M Faretta, M Lupi, F Montalenti, F Viale, ... International journal of cancer 93 (3), 401-408, 2001 | 99 | 2001 |
Identification of 4,5-Dihydro-1H-pyrazolo[4,3-h]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors I Beria, D Ballinari, JA Bertrand, D Borghi, RT Bossi, MG Brasca, ... Journal of medicinal chemistry 53 (9), 3532-3551, 2010 | 90 | 2010 |
In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation M Scabini, F Stellari, P Cappella, S Rizzitano, G Texido, E Pesenti Apoptosis 16, 198-207, 2011 | 89 | 2011 |
Multiparametric cell cycle analysis by automated microscopy F Gasparri, P Cappella, A Galvani Journal of biomolecular screening 11 (6), 586-598, 2006 | 80 | 2006 |
FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients RA Tassi, P Todeschini, ER Siegel, S Calza, P Cappella, L Ardighieri, ... Journal of Experimental & Clinical Cancer Research 36, 1-18, 2017 | 72 | 2017 |
Cell proliferation method: click chemistry based on BrdU coupling for multiplex antibody staining P Cappella, F Gasparri, M Pulici, J Moll Current protocols in cytometry 72 (1), 7.34. 1-7.34. 17, 2015 | 61 | 2015 |
Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo U Cucchi, LM Gianellini, A De Ponti, F Sola, R Alzani, V Patton, A Pezzoni, ... Anticancer research 30 (12), 4973-4985, 2010 | 60 | 2010 |
Simulating cancer-cell kinetics after drug treatment: application to cisplatin on ovarian carcinoma F Montalenti, G Sena, P Cappella, P Ubezio Physical Review E 57 (5), 5877, 1998 | 59 | 1998 |
Measuring the complexity of cell cycle arrest and killing of drugs: Kinetics of phase‐specific effects induced by Taxol G Sena, C Onado, P Cappella, F Montalenti, P Ubezio Cytometry: The Journal of the International Society for Analytical Cytology …, 1999 | 58 | 1999 |
Thieno[3,2-c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity S Bindi, D Fancelli, C Alli, D Berta, JA Bertrand, AD Cameron, P Cappella, ... Bioorganic & medicinal chemistry 18 (19), 7113-7120, 2010 | 39 | 2010 |
Synthesis of novel, simplified, C-7 substituted eleutheside analogues with potent microtubule-stabilizing activity D Castoldi, L Caggiano, P Bayón, AM Costa, P Cappella, O Sharon, ... Tetrahedron 61 (8), 2123-2139, 2005 | 37 | 2005 |
Interpreting cell cycle effects of drugs: the case of melphalan M Lupi, P Cappella, G Matera, C Natoli, P Ubezio Cancer chemotherapy and pharmacology 57, 443-457, 2006 | 34 | 2006 |
Identification of Myb-binding protein 1A (MYBBP1A) as a novel substrate for aurora B kinase C Perrera, R Colombo, B Valsasina, P Carpinelli, S Troiani, M Modugno, ... Journal of biological chemistry 285 (16), 11775-11785, 2010 | 30 | 2010 |