| Structure-based stabilization of non-native protein–protein interactions of coronavirus nucleocapsid proteins in antiviral drug design SM Lin, SC Lin, JN Hsu, C Chang, CM Chien, YS Wang, HY Wu, US Jeng, ... Journal of medicinal chemistry 63 (6), 3131-3141, 2020 | 110 | 2020 |
| Up-regulation of Bax and endonuclease G, and down-modulation of Bcl-XL involved in cardiotoxin III-induced apoptosis in K562 cells SH Yang, CM Chien, MC Lu, YH Lin, XW Hu, SR Lin Experimental & molecular medicine 38 (4), 435-444, 2006 | 75 | 2006 |
| Cardiotoxin III induces apoptosis in K562 cells through a mitochondrial‐mediated pathway SH Yang, CM Chien, MC Lu, YJ Lu, ZZ Wu, SR Lin Clinical and experimental pharmacology and physiology 32 (7), 515-520, 2005 | 64 | 2005 |
| Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231 cancer cells KL Lin, JC Su, CM Chien, PW Chuang, LS Chang, SR Lin Toxicon 55 (7), 1263-1273, 2010 | 61 | 2010 |
| MECHANISMS OF CARDIOTOXIN III-INDUCED APOPTOSIS IN HUMAN COLORECTAL CANCER COLO205 CELLS. CH Tsai, SH Yang, CM Chien, MC Lu, CS Lo, YH Lin, XW Hu, SR Lin Clinical & Experimental Pharmacology & Physiology 33 (3), 2006 | 58 | 2006 |
| Induction of apoptosis in human leukemia K562 cells by cardiotoxin III SH Yang, MC Lu, CM Chien, CH Tsai, YJ Lu, TC Hour, SR Lin Life Sciences 76 (21), 2513-2522, 2005 | 49 | 2005 |
| Effects of Cardiotoxin III on NF- B Function, Proliferation, and Apoptosis in Human Breast MCF-7 Cancer Cells CC Chiu, KL Lin, CM Chien, LS Chang, SR Lin Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 17 …, 2009 | 47 | 2009 |
| Naphtho [1, 2-b] furan-4, 5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation KL Lin, JC Su, CM Chien, CH Tseng, YL Chen, LS Chang, SR Lin Toxicology in Vitro 24 (1), 61-70, 2010 | 44 | 2010 |
| Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells YJ Lu, SH Yang, CM Chien, YH Lin, XW Hu, ZZ Wu, MJ Wu, SR Lin Toxicology in Vitro 21 (1), 90-98, 2007 | 43 | 2007 |
| Involvement of c-jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by cardiotoxin III (Naja naja atra) in K562 leukemia cells SH Yang, CM Chien, LS Chang, SR Lin Toxicon 49 (7), 966-974, 2007 | 39 | 2007 |
| Hyaluronic acid–povidone-iodine compound facilitates diabetic wound healing in a streptozotocin-induced diabetes rodent model RF Chen, CT Wang, YH Chen, CM Chien, SD Lin, CS Lai, CJ Wang, ... Plastic and reconstructive surgery 143 (5), 1371-1382, 2019 | 37 | 2019 |
| Involvement of both endoplasmic reticulum-and mitochondria-dependent pathways in cardiotoxin III-induced apoptosis in HL-60 cells. CM Chien, SH Yang, LS Chang, SR Lin Clinical & Experimental Pharmacology & Physiology 35 (9), 2008 | 37 | 2008 |
| Naphtho [1, 2-b] furan-4, 5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway CM Chien, KL Lin, JC Su, PW Chuang, CH Tseng, YL Chen, LS Chang, ... European journal of pharmacology 636 (1-3), 52-58, 2010 | 36 | 2010 |
| Naphtho [1, 2-b] furan-4, 5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells JC Su, KL Lin, CM Chien, CH Tseng, YL Chen, LS Chang, SR Lin Life sciences 86 (5-6), 207-213, 2010 | 35 | 2010 |
| Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells CM Chien, SY Chang, KL Lin, CC Chiu, LS Chang, SR Lin Toxicon 56 (4), 508-520, 2010 | 33 | 2010 |
| Structural basis for targeting T: T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA CM Chien, PC Wu, R Satange, CC Chang, ZL Lai, LD Hagler, ... Journal of the American Chemical Society 142 (25), 11165-11172, 2020 | 29 | 2020 |
| Half-sandwich Ru (η6-p-cymene) complexes featuring pyrazole appended ligands: Synthesis, DNA binding and in vitro cytotoxicity YC Huang, J Haribabu, CM Chien, G Sabapathi, CK Chou, R Karvembu, ... Journal of Inorganic Biochemistry 194, 74-84, 2019 | 28 | 2019 |
| Novel indoloquinoline derivative, IQDMA, induces G2/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation JC Su, KL Lin, CM Chien, CM Lu, YL Chen, LS Chang, SR Lin Life sciences 85 (13-14), 505-516, 2009 | 28 | 2009 |
| Novel indoloquinoline derivative, IQDMA, suppresses STAT5 phosphorylation and induces apoptosis in HL-60 cells CM Chien, SH Yang, KL Lin, YL Chen, LS Chang, SR Lin Chemico-biological interactions 176 (1), 40-47, 2008 | 28 | 2008 |
| Recipient adipose-derived stem cells enhance recipient cell engraftment and prolong allotransplant survival in a miniature swine hind-limb model YR Kuo, CC Chen, YC Chen, CM Chien Cell transplantation 26 (8), 1418-1427, 2017 | 27 | 2017 |
